T3 source : Hi there I’m desperately seeking a... - Thyroid UK

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T3 source

SLP01 profile image
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Hi there

I’m desperately seeking a source of T3. (Non prescription) I have a rT3 issue and would like to try a T3 only approach. Is anyone able message me privately? Thanks

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SLP01
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greygoose profile image
greygoose

Taking T3 does not 'cure' rT3. High rT3 can be caused by many things. One of them, of course, is having high FT4 and low FT3, due to a conversion problem. In that case, what lowers the rT3 is reducing the levo and adding T3 in its place. But it is not the T3 itself that lowers rT3, it's having a lower FT4.

However, high rT3 can be caused by many things, like high cortisol, or low ferritin.

T3 without prescription is very difficult to find, these days. But, you might get more help if you post your actual blood test results. :)

MaisieGray profile image
MaisieGray

I would put it this way, we don't have a problem because our RT3 level is high; our RT3 is high because we have a problem..... So for instance, at a time of illness, stress, dieting etc etc reverse T3 may increase accordingly. Research in rats has shown RT3 to have a specific neuro protective function, and more research is underway to prove the hypothesis that "a deiodinase II (D2) inhibitor reverse triiodothyronine (rT3) may render brain specific hypometabolic state to ensure reduced damage during an acute phase of cerebral ischemia without affecting circulating thyroid hormone levels". It certainly isn't the case that there's a magic formula that proves we have a RT3 problem as perpetuated by certain advocates of the "ratio", nor is it scientifically proven that RT3 blocks T3 receptors.

Helcatamy profile image
Helcatamy

Hi I’m also seeking T3 supplies and nowhere I find online seems legit! Would be so grateful if someone can PM me a reputable source as my T4 is just not helping and I am so desperate now I must try and see if this will help get rid of the damn brain fog!

SLP01 profile image
SLP01

Thanks for your responses. I’m waiting for my latest blood test results so will post again once received. Thanks.

shaws profile image
shawsAdministrator

This is a copy of an explanatio of RT3 by one of our deceased Adviser/scientist:

This is from Dr. Lowe:

"Dr. Lowe: Some readers will not be familiar with reverse-T3, and I know from experience that many others harbor misconceptions about the molecule. Because of this, I have summarized in the box below what we know about reverse-T3. I've answered your question below the summary.

Conversion of T4 to T3 and Reverse-T3: A Summary

The thyroid gland secretes mostly T4 and very little T3. Most of the T3 that drives cell metabolism is produced by action of the enzyme named 5'-deiodinase, which converts T4 to T3. (We pronounce the "5'-" as "five-prime.")

Without this conversion of T4 to T3, cells have too little T3 to maintain normal metabolism; metabolism then slows down. T3, therefore, is the metabolically active thyroid hormone. For the most part, T4 is metabolically inactive. T4 "drives" metabolism only after the deiodinase enzyme converts it to T3.

Another enzyme called 5-deiodinase continually converts some T4 to reverse-T3. Reverse-T3 does not stimulate metabolism. It is produced as a way to help clear some T4 from the body.

Under normal conditions, cells continually convert about 40% of T4 to T3. They convert about 60% of T4 to reverse-T3. Hour-by-hour, conversion of T4 continues with slight shifts in the percentage of T4 converted to T3 and reverse-T3. Under normal conditions, the body eliminates reverse-T3 rapidly. Other enzymes quickly convert reverse-T3 to T2 and T2 to T1, and the body eliminates these molecules within roughly 24-hours. (The process of deiodination in the body is a bit more complicated than I can explain in this short summary.) The point is that the process of deiodination is dynamic and constantly changing, depending on the body's needs."

and

toopoopedtoparticipate.com/...

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