Low Dose Naltrexone (LDN) treatment for Hashimo... - Thyroid UK

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Low Dose Naltrexone (LDN) treatment for Hashimoto's?

vocalEK profile image
13 Replies

This is a new one on me. Has anyone tried this? Know anything about it? Wonder if it can be used for those who are poor converters.

ldnscience.org/lp/ldn-slowi...

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vocalEK
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SeasideSusie profile image
SeasideSusieRemembering

vocalEK

If you are on a PC, look to the right of the screen and you will see RELATED POSTS near the top, click on those and see what's been said previously.

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shaws profile image
shawsAdministrator

If you contact this member is quite knowledgteable and I believe it helped her condition.

healthunlocked.com/user/maryf

MissFG profile image
MissFG

Here’s some info that will help.

I’ve researched LDN and it doesn’t work for everyone. But it can help lower antibodies for some with hashimotos.

As the link states you can get a private prescription cheap enough on line with a consultation and start low and increase slowly.

ldnresearchtrust.org/what-i...

G2G2 profile image
G2G2

I was on LDN for many months. Zero side effects. It lowered my antibodies, but not significantly.

fortunata profile image
fortunata

I’ve been taking LDN, 4.5mls every morning, for almost nine months. I don’t know if it’s lowered my antibodies as I haven’t had them tested for a while but I feel amazingly well. Much better than I did. I sleep like a log at night, am able to exercise and feel a lot less ‘inflamed’ than I did.

CornishChick profile image
CornishChick in reply tofortunata

May I ask when in the day you take your dose please? I’m also considering taking LDN and have chronic insomnia and crazy high antibodies, so am interested to see if it helps me too.

Hashi-hacker profile image
Hashi-hacker in reply toCornishChick

Hi, I take my LDN 4.5mls at night, just before bed. Can't say it affects my sleep positively or not. What did make a bigger difference for sleep was sorting out my adrenals but that's a whole other story! Think LDN helped drop my Hashi antibodies and general immune boost e.g. don't get so many colds, and weirdly years long back pain eased off.

fortunata profile image
fortunata in reply toCornishChick

It made me wakeful at night if I took it before bed. I take my Liothyronine at 7.30 am and wait two hours. I have a 9.30am alarm to remind me to take the LDN. I sleep like a log now.

CornishChick profile image
CornishChick in reply tofortunata

Sorry I meant do you take eg before breakfast? Does it have to be taken away from thyroid meds?

fortunata profile image
fortunata in reply toCornishChick

I would definitely take it well away from thyroid meds.

Hillwoman profile image
Hillwoman

I've taken LDN at 4.5mg daily since 2015. I haven't tested my thyroid antibodies during that time, so I don't know whether it has affected them.

The reason I started on it was to manage early RA in my hands and wrists, because I was becoming really disabled. It's been very effective for the pain and inflammation. I still have plenty of other health issues though.

jjf255 profile image
jjf255

I have written in past posts about my husband taking LDN 3.5 mg to try to lower his thyroid antibodies. He just had new blood work and a drs. visit and his antibodies have come down slightly. What I believe the LDN has mainly done is stopped the antibodies from increasing. For several years his antibodies were constantly increasing. He has taken LDN for about a year now and at 3 month and 6 month blood test the antibodies had stopped increasing. Now with this last test they went down slightly...not significantly though. His dr. has just written his new LDN script for 4.5 mg to see if the increase may help more. My husbands LDN is compounded at a local pharmacy and the instructions have been to take just before going to bed. If you read up on LDN you will see what the reasoning is for taking it at bedtime. He never had any side effects and vivid dreams for about a week are the only side effect that some people seem to have. My husbands dr. did say LDN works for some and not for others.

MaisieGray profile image
MaisieGray in reply tojjf255

The more current advice generally is that morning dosing works just as well, and for some who experience problems with night time dosing, better.

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