Frontiers in Thyroid Endocrinology have informed me that our eBook collection of papers is now available from the site:
Tihs collection is a large part of our work that shows a) the individual nature of thyroid function parameters (i.e. each person occupying their own narrow range within the much wider general populaion range), b) the incorrectness of using the healthy TSH normal range as a diagnostic for therapy, c) the effects of nonthyroidal illness on thyroid parameters, d) the important role of direct T3 production by the thyroid as a controller of T4-T3 conversion by the rest of the body, e) the absolute need to monitor FT3 in therapy, f) the collapse of the control system when all thyroid activity is lost and the resulting fundamental change in T4-T3-TSH relationships. and g) because of individuality in thyroid parameters and response to treatment, the need to go back to patient symptom presentation as a key part of diagnosis and treatment. The overarching message is the individuality of patients and the resulting essential need to treat them as individuals rather than the "shoehorning" present diagnostic approach of "in or out of the normal range". It also urges a serious examination of combined T4/T3 therapy in suitable patients (no matter T4/T3 or NDT).