Small intestinal bacterial overgrowth (SIBO) is a condition that is characterized by too many microorganisms in the small intestine. Unlike the large intestine or colon, which is extraordinarily rich in bacteria, the small intestine usually has much less bacterial organisms.
An excellent self help explanation from Dr Jockers on 14 strategies to rebalance SIBO (small intestine bacterial overload).
The small intestine typically has less than 104 organisms per millilitre. Anything above this level is classically considered to be SIBO (1). This bacterial overgrowth can be a combination of both good (progenic) and bad (pathogenic) microorganisms.
SIBO damages the intestinal lining and creates a state of mild-severe leaky gut syndrome and resulting food allergies, sensitivities and chronic inflammatory processes (2).
I reckon it’s a chicken and egg conundrum as to which comes first.
SIBO, HPylori, vagus nerve inflammation , adrenal dysfunction, drop in mineral and vitamin status due to SIBO and replacement with lurking heavy metals to name a few. This then takes us down the road of chronic clinical hypothyroidism which can only be picked up by testing reverse T3.
Thank you mourneadventurer for this amazing link. It is rammed packed full of vital info. I have been wondering how to check if I have SIBO but can't afford any tests at the moment. Even a link within your link to ADHD, which my 37 year old son seems to have. x
I’m glad you’re getting benefit from the link @marigold22 . Even without testing there are suggestions which might be easy to introduce. The gut -brain connection is a crucial part of the jigsaw regarding behaviour, depression, anxiety and as I am experiencing heart rate.
Thanks. My Big Turnaround came after I did the AIP diet for 6 weeks. I think I cleared a lot out with that way of eating; discovered all grains are my no-no. But I was still wondering about gut health. OMG it's all so complicated. But after 36 years of chronic illness, I'm now more or less mended. I hope you are recovering with the help of this most amazing forum. x
PS Just read your profile.... I was diagnosed hypo in 1981, in 2017 discovered via private blood test that it's Hashi's; also did the DIO2 as you did, and confirmed what I already thought, ie faulty thyroid gene from one parent.
Hello @marigold22 having a DIO2 genetic polymorphism predisposes us to being unable to methylate and detox properly. Being treated with T4 only makes the situation worse but to all appearances with NHS tests we are within range. In the meantime the liver and gall bladder detox pathways become clogged and conversion of T4 to active T3 can’t take place.
This toxic environment lends itself to all of the nasty unwanted passengers as we become more unwittingly hypothyroid. I’ve found it helpful to reduce the toxic load with herbs, reinoculate with beneficial bacteria and alter my diet accordingly. Remineralisation has been the key to my recovery.
Quicksilver Scientific do a liposomal GI detox and when I’m ready I’ll start the Black box 2. The European distributor is ProActive Healthcare. Dr Chris Shade of Quicksilver Scientific does some excellent podcasts describing the process of detoxing correctly so as not to retox ourselves with heavy metals. Dr Chris is engaging and informative so your son might also benefit?
Best Wishes marigold22 we are the lucky ones as we know we don’t methylate or detox properly so we’re able to learn to support ourselves and our faulty genes by actively taking key supplements.
I knew zero about methylation, and in fact had never heard the word, until I paid for the DIO2 gene test. It was the counsellor lady who phoned me with my results who talked at great length about methylation. Even then (in Jan. 2017) my brain didn't take it in, I wrote some notes, but ignored it all. Then I did read an article about a month ago, and discovered that all B vitamins (there are 8) assist methylation. As it happened, I had started on a high dose multi B supplement and I think those along with the AIP diet turned a massive corner for me. There are, I'm sure other things to do and take, to help with methylation which, again, I must re-read. Sadly earning some money must take top priority currently.
I will though save and read your link, it will take a few readings and hours for it to all sink in. x
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Underactive Thyroid
hashimotos, SIBO, perimenopause, head injury, any advice welcome! 
Hives, stomach issues, caffeine
Suddenly high TSH
Advice on my array of recommended supplements (per endocrinologist”s recommendations)
