Our paper, which asks whether radomised clinical trials have achieved their objective, and why physiological findings and clinical trial results don't agree has been published today. It is an open journal: J Thyroid Research.
hindawi.com/journals/jtr/20...
This paper and the paper I deposited (Fisher et al) with Louise Roberts together severely question the value of clinical trials so far performed and their conclusions, and suggest better ways of proceeding in future.
Fabulous!
Great, diogenes!
What will it take for doctors to give us the thyroid medicines we need without such a giant, global widespread hassle? I have an idea. Make a big balloon of a doctor with a scowl on his face fighting with a patient as they vie for a prescription of T3 or NDT with the doctor winning. Fly it over Westminster, gather thousands of thyroid patient demonstrators, call CNN and lots of international reporters then send the balloon on a world tour! Maybe instead of diapers and orange hair dress him in a prison guard outfit! Use big hands so he can grab as much meds from the patient as possible, Just a thought. irina
Yes, I think that should do it!
Excellent diogenes Well done to all involved.
Lets hope others take notice.
Isn't it true that only a very small % of these clinical trials get to publication anyway? Presumably only the ones they can manipulate to show the desired results? Just another form of 'lies damn lies and statistic'...swap statistics for RCT!
Very interesting. Will it make a difference to treatment? I am tempted to print this off and leave it at my surgery, although I’ve done this before and it hasn’t made any impact.
It should do, because the ground on which recommendations (or not) for combination treatment, dangers of osteoporosis, or AF lie is swept away. The basic finding is that you cannot do a randomised clinical trial and safely extrpolate its findings from the group to the individual. That is the absolute centre of the argument. So if collective biochemistry does not apply to individual biochemistry, we are left with presentation of symptoms first, + biochemistry later.
Diogenes, this paper is like the whipped cream and cherry on top of the sundae. Well done. Should be quite a force when combined with Fisher et al. PR
Sub-clinical Hypothryoid - trial project
