When will T3 kick in ?

Milpol

You should retest 6 weeks after a change in dose (I have found that I need 8 weeks to feel the full benefit and for my results to stabilise).

Everyone is different. When I started adding T3 to my Levo I didn't feel anything at all, I increased gradually, tweaked both Levo and T3 for quite a while and eventually realised that I was feeling better than I did. It showed in my results before I felt it really. I never had a moment of "Wow! I can really feel the difference T3 has made" like some people do.

I felt the difference, though only temporary, within hours with adding T3 initially as tiny 3.12 mcg dose, though slowly over following month or so got up to 25 mcg. I was stuck 24/7 on my sofa over winter and now walking 10,000 steps daily but still falling asleep in the afternoon, some pain, hair falling out ( tho that can be the T3 itself), no weight loss etc. So better but some way to go- certainly felt hypo again last week when up north it got relatively cool again and I was back in my winter coat, socks, 2 layers and blanket!