Explanation of these results please

[macduart12]

I’m on 75 Levi thyroxine

Thyroid peroxidase antibody level 1430 IU/mL [< 60.0]

[SlowDragon Administrator]

You antibodies are very high this is Hashimoto's, (also known by medics here in UK more commonly as autoimmune thyroid disease).

About 90% of all hypothyroidism in Uk is due to Hashimoto's

75mcg is not a high dose. Can you add your most recent Thyroid test results and ranges- TSH, FT4 and FT3

Essential to test vitamin D, folate, ferritin and B12.

Always get actual results and ranges. Post results when you have them, members can advise

Hashimoto's affects the gut and leads to low stomach acid and then low vitamin levels

Low vitamin levels affect Thyroid hormone working

Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances. Most common by far is gluten

According to Izabella Wentz the Thyroid Pharmacist approx 5% with Hashimoto's are coeliac, but over 80% find gluten free diet helps significantly. Either due to direct gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)

But don't be surprised that GP or endo never mention gut, gluten or low vitamins. Hashimoto's is very poorly understood

Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and slowly lower TPO antibodies

Ask GP for coeliac blood test first

thyroidpharmacist.com/artic...

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amymyersmd.com/2017/02/3-im...

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[macduart12 in reply to SlowDragon]

T4 is 16pmol/L (9-25.0)

T-SH LEVEL IS 8.2miu/L ( 0.3-5.0)

[SlowDragon Administrator in reply to macduart12]

You are seriously under medicated

Dose of Levothyroxine should be increased in 25mcg steps until TSH is around one and FT4 towards top of range and FT3 at least half way in range.

Ask for 25mcg dose increase in Levothyroxine retesting after 6-8 weeks

Plus ask that vitamin D, folate, ferritin and B12 are tested. Likely low when under medicated

Detailed supplements advice on Low vitamins due to under medication

healthunlocked.com/thyroidu...

Always take Levo on empty stomach and then nothing apart from water for at least an hour after. Many take on waking, but it may be more convenient and possibly more effective taken at bedtime

verywell.com/should-i-take-...

Many people find Levothyroxine brands are not interchangeable. Once you find a brand that suits you, best to make sure to only get that one at each prescription.

All thyroid tests should be done as early as possible in morning and fasting and don't take Levo in the 24 hours prior to test, delay and take straight after. This gives highest TSH, lowest FT4 and most consistent results

[macduart12]

Any idea how to reduce the antibody result .... it looks really high to me ! And why doesn’t my gp tell me about when to take it .... what to avoid and the importance of these other tests ... arghhhhh