Hi, my daughter was diagnosed hypothyroid in 2014 and I am worried about her dose being adjusted. She has had it reduced from 200mcg levothyroxine to 50mcg by her endocrinologist and her symptoms are tiredness, pins and needles, cold intolerance, depression, hair loss, weight gain, joint aches.
Advice appreciated.
Nov 2017
TSH 0.08 (0.2 - 4.2)
Free T4 20.3 (12 - 22)
Free T3 4.1 (3.1 - 6.8)
Written by
Kolo69
To view profiles and participate in discussions please or .
If your daughter's endocrinologist understood the first thing about thyroid medication s/he would know that dose adjustments should be gradual, usually in 25mcg increments, not swingeing 150mcg cuts.
There was no reason to reduce dose based on those results. TSH was suppressed and that is probably what prompted the dose reduction but your daughter's FT4 and FT3 were within range so she wasn't overmedicated.
She has been on 50mcg since last week. She does not accept the reduction and she does not accept the results since they were done 3 weeks earlier than her endocrinologist suggested.
Whether the endo is right or wrong about TSH being too suppressed (and it is debatable) the endo is not right to make such a swingeing cut in dose. Dose should have been reduced to 175mcg and thyroid levels retested 6-8 weeks later.
I don't know how your daughter will get around this. If she has a supportive GP perhaps the GP could speak to the endo or better still another endo for a second opinion.
Doctors and endocrinologist seem to have the same type of training, i.e. adjust doses willy/nilly to try to keep the TSH 'in range' whereas their treatment is causing the patients extreme difficulties.
I don't think Endocrinologists and doctors are aware that if patient is hypothyroid that their gland doesn't produce sufficient, and they should prescribe sufficient to keep our TSH 1 or lower and concentrate more on the FT4 and FT3 and patient's clinical symptoms (of which they dont know ONE). Your daughter's FT3 could be a little higher.
Dr Toft, past president of the British Thyroid Association and leading endocrinologist, states in Pulse Magazine,
"The appropriate dose of levothyroxine is that which restores euthyroidism and serum TSH to the lower part of the reference range - 0.2-0.5mU/l.
In this case, free thyroxine is likely to be in the upper part of its reference range or even slightly elevated – 18-22pmol/l.
Most patients will feel well in that circumstance. But some need a higher dose of levothyroxine to suppress serum TSH and then the serum-free T4 concentration will be elevated at around 24-28pmol/l.
This 'exogenous subclinical hyperthyroidism' is not dangerous as long as serum T3 is unequivocally normal – that is, serum total around T3 1.7nmol/l (reference range 1.0-2.2nmol/l)."
You can obtain a copy of the articles from Thyroid UK email dionne.fulcher@thyroidUK.org. print it and highlight question 6 to show your doctor.
If she did need to lower dose (which may not be true) the absolute maximum it should be reduced is 25mcgs. Never such vast dose changes. This underlines that her endo is not a thyroid specialist, probably a Diabetes endo
All thyroid tests should be done as early as possible in morning and fasting and don't take Levo in the 24 hours prior to test, delay and take straight after. This gives highest TSH, lowest FT4 and most consistent results
You need a new endo and fast
Email Thyroid UK for list of recommended thyroid specialists dionne.fulcher@thyroidUK.org
Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.
Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.