Isolated hyperthyroxinemia

[Stelladog1]

Can anyone tell me if they have heard of isolated hyperthyroxinemia , my endo specialist says I have this ??

[diogenes Remembering]

This is a description of the presentation details and prognosis from Medscape:

Euthyroid hyperthyroxinemia is defined as a condition in which the serum total thyroxine (T4) and triiodothyronine (T3) concentrations are increased, but the thyroid-stimulating hormone (TSH) concentration is normal and there are no clinical signs or symptoms of thyroid dysfunction. These changes may be transient or persistent.

In the past, euthyroid hyperthyroxinemia was a diagnostic challenge and many patients were inappropriately treated for thyroid disease. Today, serum TSH is a screening test for thyroid function, and a normal TSH value should not be followed by measurement of total T4. In these circumstances, euthyroid hyperthyroxinemia frequently remains undetected with no harm to the patients.

[Stelladog1 in reply to diogenes]

But I do definitely have symptoms of underactive thyroid and was diagnosed by the late Dr Skinner who Brought back sick people from zombies to optimal health .

I have been very well since I was started on thyroxine and T3 over ten years ago ,but last year because I had a low t4 but normal TSH I was advised by gp to come off the meds altogether ,and now I am back to square one ,with no quality of life and been told I have this condition which I have never heard of .

[diogenes Remembering in reply to Stelladog1]

Then you haven't got it. If you had low T4 and normal TSH, this isn't hyperthyroxinemia but hypothyroxinemia which might very well indicate inadequate treatment. If you have high FT4/FT3 I should be very surprised.

[Stelladog1 in reply to diogenes]

Sorry Diogenes I made a error it is hypothyroxinemia

[Stelladog1]

I have just read a copy of a letter the specialist wrote to my gp which states I have hypothyroxinemia and he states i dont need thyroxine therapy but I have checked the copy to another specialist he is sending me to see and that one says I have hyperthyroxine, so I am very confused which one it is

[diogenes Remembering]

This seems a bit confusing. It might be clearer if you posted the TSH value that was supposed to be "normal". If above 3 or 3.5 the chances of that being "normal" are much lower - the thyroid is stuggling. On the other hand if the TSH was around 1 then with below normal FT4 that indicates something wrong with the pituitary.

[Stelladog1]

Hi again with reference to your last reply ,the last TSH in July was 2.8 T4 was 11 and T3 was 6.3

[Stelladog1]

I am really struggling to get through each day now ,don't know what else I can do to feel back to normal or near to it