I am on Letrozole and Levothyroxine, both cause bone thinning. I had a dexa scan 18 months ago when I was prescribed the letrazole for breast cancer, which showed extensive bone loss already. Doctor wanted to put me on Alendronic Acid but am scared after reading about the side affects. I've been on levothyroxine for almost 30 years and never felt well. I've got terrible joint pain plus hiatus hernia/reflux. I was on omaprazole for years and then statins for high cholesterol. I had to stop the statins as my bone pain was so bad. I stopped the omaprazole when I read it decreased absorbtion of levothyroxine. I've seen every doctor in my practice over the years and not one has really helped. I've even paid for private blood testing a few years ago but my GP practice wouldn't even look at the results! I no longer work so cannot afford more private testing or to buy natural thyroid drugs. Not sure if anyone has any suggestions to make but I felt this was the only place left to try!