I noted a post from 4 years ago on this topic and wanted to raise it again to see if anyone had thoughts on how things have changed since that time. It was an interesting thread:
I've been on T4 for 20 years - never had any part of thyroid removed but many years in they did do a scan and I think the results were that thyroid was indicative of post-treatment condition. I've been on 150mcg T4 for over 10 years - appear not to be converting well to T3 based on Reverse T3 labs (and have tried supplements and other things to lower cortisol, etc.) and have had issues with sleep, anxiety, agitation, etc. which I think result from having too high a T4 as Free T4 is always slightly above or at top of T4 range (Free T3 is low at about a third of range). Does a thyroid still function even after 20 years of treatment? I read somewhere in the past that once you get to a full replacement dose it really takes over and your thyroid slowly stops producing its own. So if that is the case, based on the figures in the spreadsheet in the post above and my particulars, I think I should be on a lower dose. If the thyroid DOES still have some function I still think I should be on a lower dose based on my particulars (76 kgs, 1.72 meters, male 42 years old). I am considering dropping my T4 med down to 125 based on what I see here and see if that helps me symptom-wise and then perhaps work on boosting Free T3 otherwise (e.g., lowering cortisol, supplements to assist with conversion again, etc.). Basically, I think I have too much T4 medication in me and it's keeping me too wired for my own good. Any thoughts? Great resource the earlier post was! Thank you.