OCD bad and anger issues are taking over my life at the minute and making my partner and I argue a lot. I have recently come off antidepressants (8 weeks ago approx) and upped my thyroxine by 25mcg to 150mcg a day. I have always been obsessed with cleaning but it's a lot worse at the mo and I am getting so angry at the slightest thing that I'd have tolerated before, I feel I have widened round the waist and if anything put on weight and feel exhausted all the time, has anyone got any advice on how I can solve my anger issues and save my relationship. Could I be taking too much thyroxine or do I had to except I need antidepressants to chill out! I am close to tears with frustration.