T3, I feel hypo in the evening

[adin]

Hello, me again. I have taken 5mcg T3+100mcgT4 in the morning and I don't know why I feel hypo in the afternoon & evening (and some dizziness). I thought that T3(thybon) it is too weak or maybe 5mcg dose it is insufficient.

Thank you.

[Clutter]

Adin, 5mcg is a very small dose. Try a second dose of 5mcg 1-2 hours before the hypo symptoms kick in.

_________________________________________________________________________________________

I am not a medical professional and this information is not intended to be a substitute for medical guidance from your own doctor. Please check with your personal physician before applying any of these suggestions.

[adin in reply to Clutter]

Thank you Clutter for your good advices but, for example; Today I take in the mornig(7am) my combo dose and I feel around 11am "the hypo symptoms kick in" and I tried to took a small dose(I think around 1-2 mcgT3) but I became anxious and breathless, now I'm hypo again. I'm on t3 from a few days. What am I doing wrong.

Thank you again.

[Clutter in reply to adin]

Adin, Not sure that you are doing anything wrong, some people don't tolerate much T3 and it may be that T4 dose needs increasing. It's hard to advise without seeing recent thyroid results with ranges (figures in brackets after results). If you have results for ferritin, vitamin D, B12 and folate please post those too.

[adin in reply to Clutter]

Ohh, I forgot.

So, I'm 46 old male. I had RAI(due to Graves) in late 2012 and I became hypo in May 2013. My normal weight it was around 87kg, now it is 106kg and I still gain.

-values in November 2015; TSH 0,74(0,5-4,7); fT4 18(10,3-24,4); fT3 4,07(3,6-6,8) on 100mcg levo & 1/4ndt(nature throid).

-values in feb.(04.02'16); TSH 0,023; fT4 25,54; fT3 6,22 on 150mcg levo & 1/2 ndt(split in two).

-salivary cortisol; 8am-7,81nmol/L(3,2-19,1), 3pm-2,23(1,8-11,9) and 23pm-1,19(0,4-4,9).

-A.TPO-529UI/ml <34

-PTH is 47,3(15-65)

-ferritin -240ng/ml(30-400); iron is 87(59-158)

-cholesterol 230mg/dl.

I have not done yet B12,folate and Dvit.

Now I'm on 100mcg levo and 5mcg T3 in the morning.

[Clutter in reply to adin]

Adin, Feb results show suppressed TSH, FT4 slightly over range with FT3 high in range.

You were on sufficient doses of Levothyroxine and NDT, possibly a little too much. 1/2 grain NDT contains 4.5mcg T3 so 5mcg T3 is appropriate.

Perhaps you could try taking the 5mcg T3 dose in the afternoon instead of in the morning with Levothyroxine. If that doesn't help, reduce Levothyroxine by 12.5mcg by taking 125/150mcg alternate days for a week, resume 5mcg T3 in the morning and then try a 2nd dose 5mcg T3 in the afternoon/evening.

Ferritin is good. It is worth having vitD, B12 and folate tested.

____________________________________________________________

I am not a medical professional and this information is not intended to be a substitute for medical guidance from your own doctor. Please check with your personal physician before applying any of these suggestions.

[adin in reply to Clutter]

I will try as you said Clutter, but my main problem remains gaining weight(face puffiness, sleep apnea). I read on this forum, many people who took t3 (with or without t4) lost their weight and I do not know if this would happen it to me, I hope so. Maybe this T3 that I use(Thybon) is too weak/less potent. ndt was like a booom for me but on this t3 i don't feel the same.

Thank you Clutter.

[Clutter in reply to adin]

Adin, 5mcg T3 won't feel the same as the 1/2 grain NDT which also has T4 in it.

Why have you switched from NDT to T3?

[adin in reply to Clutter]

I switched because some ladies on STTM told me very imperative that it is a bad thing to combine the levo and ndt (due to reverse t3), could pose a risk to become more hipo. And I decided to listen to them and try t3. :))

[Clutter in reply to adin]

Adin, If you felt better on Levothyroxine and NDT I should resume it and ignore what they say on STTM. I think you should reduce Levothyroxine to 125/15mcg alternate days though.

__________________________________________

I am not a medical professional and this information is not intended to be a substitute for medical guidance from your own doctor. Please check with your personal physician before applying any of these suggestions.

[adin in reply to Clutter]

I think I felt better on levo&ndt but it's too soon to make a conclusion. I'm on t3 and levo only for several days. Maybe I should try another T3 product, some stronger. I dont know.

[Clutter in reply to adin]

Adin, Thybon Henning has a good reputation. I doubt their T3 lack potency. If it did you wouldn't have had the reaction when you increased by 1-2mcg.

[thyroidnodules in reply to adin]

I tried taking half a 25mcg tablet for about four weeks and initially felt better but then developed swelling in my left leg and breathless - doc told me to straight into hospital as it could be a blood clot but I stopped taking thet3and things got better -I didn't tell my doc I had been taking t3. I didn't lose any weight butI seemedto stop gaining

[marsaday]

Use the T3 in the afternoon and see if you get a change. The T3 will interact with a different level of cortisol. This relationship between the T3 and cortisol is often the key to why things don't work as well. Your cortisol may be lower or higher in the afternoon and so it can have a different effect on how the T3 is used than in the morning.

Also possibly try taking the T4 at bedtime as this can have better effect in people (it does me).

The best thing to do is trial and error with timings. If you never experiment you will never find out what works best for your body. Today for example i have tried taking 10 T3 in the morning and it just didn't work as well as 5 T3. Probably too much T3 sucking up not enough cortisol.