Haggisplant, as your thyroid fails and produces less hormone you need more replacement hormone. Weight to dose ratios are normally calculated for initial doses for patients who have had a thyroidectomy. Thereafter the dose is titrated according to TSH, FT4 and FT3 ideally, but often just TSH and FT4.
It's quite a high dose, Haggisplant, but you need what you need. There are people on 300mcg and considerably more, so your friend may not be exaggerating.
She's quite large and actually didn't know about not taking with other foods etc. so I can imagine she might be. says her next option is to have it out? I'm not sure they do that.
I've told her to ask for other tests eg celiac etc.
Haggisplant, Tell your friend to get ferritin, vitD, B12 and folate checked if she isn't feeling well. She could also post her thyroid results if she wants to know whether she is optimally medicated.
Thyroidectomy/RAI should always be a last resort and is usually done if a patient is hyperthyroid, has thyCa, or the goiter or nodule is impacting on other nearby organs.
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