I am on 125mcg thyroxine and take the whole lot at bed time. I recently decided to cut that to 100mcg (gradually) as I thought I was possibly over treated due to palpitations. Anyway, I soon discovered that 100mcg was not enough as the little early symptoms I have learnt to recognise started creeping back so I decided to add the 25mcg back in at a different time.
What I have discovered is that about 2 - 3 hours after taking this 2nd dose, I'm really mentally alert, sharp and switched on. I took just 25mcg at mid morning and was really sharp all afternoon from midday onwards.
I have also not been sleeping well since starting thyroxine, so from this revelation of sharpness, decided to switch to taking just 25mcg at night and the 100mcg in the morning. I slept really well.
Is it possible for thryoxine to have such an immediate effect of just a few hours. I didn't think it was possible with just taking T4 but my experience seem to say otherwise. Has anyone else experienced this?
Plus is it ok to split the dose long term and not take it all at once?