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The prevalence of depression and anxiety disorders in patients with euthyroid

Hashimoto’s thyroiditis: a comparative study

I've found this paper published in the General Hospital Psychiatry journal that concludes that having euthyroid Hashimotos or a euthyroid goitre increases the predisposition to major depression and anxiety disorders. So next time your GP or specialist tries to tell you that your depression has nothing to do with your thyroid perhaps s/he would like to see this:

Objective: The aim of this study was to examine the current prevalence of major depression and anxiety

disorders in patients with euthyroid Hashimoto’s thyroiditis (HT) and euthyroid goiter.

Method: The study sample was formed by consecutive 51 and 45 patients who were admitted to the

endocrinology outpatient clinic and diagnosed with euthyroid HT and endemic/nonendemic goiter,

respectively, and 68 healthy controls. Current diagnoses of psychiatric disorders were determined using

the Structured Clinical Interview for DSM-IV. Beck Depression Inventory and Beck Anxiety Inventory were

applied to the participants.

Results: There was a statistically significant difference among the three groups in terms of major depression

(P=.001), any mood or anxiety disorder (P=.000), any depressive disorder (P=.020), any anxiety disorder

(P=.016) and obsessive–compulsive disorder (OCD) (P=.013). In the HT group, the prevalence of depression

(P=.000), OCD (P=.005) and panic disorder (P=.041) was significantly higher than that in the control group.

In the goiter group, depression (P=.006), any depressive disorder (P=.03), and any mood or anxiety disorder

(P=.000) were significantly common in comparison to the control group. No significant difference was found

between the HT and goiter groups.

Conclusions: Euthyroid HT and euthyroid goiter increase predisposition to major depression and anxiety

disorders, and thyroid autoimmunity and other thyroid pathologies should be investigated in euthyroid

patients with chronic and treatment-resistant complaints.

If anyone would like the full paper please PM me.

3 Replies

Thanks for posting..


Yes pls pm me with paper :) thank you for posting, kaz


Please could you pm me as well? Thank you.


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