I recently tried taking my levo at night as I read it was a better time to take it (and I love my morning coffee). I am only on 50m - within a few days I started suffering from Plantar Fasciitis - it is not something I have suffered from before so I thought there could be a connection. I swapped back to a morning dose but that has made no difference and I also now have fatigue, cramp and joint pain. Does that indicate that possibly I need a higher dose (I have had 50m since being diagnosed as Hyper a year ago and the blood tests I have had since were said to be 'fine' but I have never seen the results)? It really is amazing to read stuff on here because when diagnosed I just assumed the meds I was given would be fine (I also have a B12 jab every 3 months) and never even asked for the readings - I'm learning now!