Just started a T4/T3 combo....

[Karlos]

Started a few days ago, how long before you would expect to feel any benefit?

Although I do realise that there could be none at all?!

Thanks...

[kimbo]

Hi Karlos i have just started mine too hope we can get some improvement soon, what are you taking at the moment dose wise of both x

[bellamish]

I'm on T3/T4 it took a good couple of weeks before I felt any different I'm on 5mg of T3 and I was on 100mg of T4 which was reduced after a month to 75.. it was only on the reduction of T4 that I started to feel the benefit, how ever it is short acting and when I crash in the afternoon it's actually worse.

I'm hoping my next visit with the endo see's an afternoon dose added which should help withuthis.

[Jackie]

HI Normally about a month to be at optimum, at 6 weeks, there should be a further test for TSH. T4 and Fre T3, then often the treatment with either t4, T3 or both increased. also do not forget all the other tests, see the site. Really vit D ( hormonal) should be done at the beginning at the very least.If D needs treatment then corrected calcium before treatment, as must always be in range, above all.You may be worse for the first few months until the levels right, it should still be done slowly for safety

Best wishes,

Jackie

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[boo16]

That's a very tiny amount of T3.

Is it not possible, do you think, that when you crash in the afternoon it is because you have felt the benefit of the T3 and actually before you started taking it became 'used' to feeling awful and the crash is not that you are worse it is just how you used to feel.

It is just that you have experienced feeling better after taking the small amount of T3 for a while which then exensuates the feeling of having a bad crash. Does that make a bit of sense?

(sorry for the spelling errors - brain waking up very slowly this morning)

[Stourie]

When I started on t3 with my t4 I felt the benefit in the first few days but I started on 10mcg and after a week upped it to 20 and felt even better. Then I just cut out the t4 although a couple of years later I am introducing a small dose of t4 again. Hope that helps

Jo xx

[vajra]

Hi K. My experience was that after about 15 years of quite severe hypothyroidism 10mcg of T3 taken with T4 produced almost instant results. The initial effect was detectable within hours - mostly in terms of improved mood and brain function.

It took months and years (and several dose increases) for the physical effects to work through - guess it can take a long time for the body to achieve a new balance after many years of hypothyroidism and auto immune problems.

One to be careful of (in my case anyway) is that while adding T3 improves wellbeing that there's a very narrow/finely tuned window indeed on the proportion and total T3/T4 dose that delivers all of the goods. Especially in terms of stamina and subtle aspects of mood, motivation and cognition.

This window is much tighter than blood testing etc picks up. Ramping up the dose from a low start makes a lot of sense.

Getting the other stuff (vits, minerals, and adrenals - especially the adrenals) right matters a lot in this respect too...

I'm another that preferes a little T4 (50 - 100mcg) with my T3 - i also find that T3 in higher proportions tends to cause a certain peakiness/falling off/slump in energy before the next dose is due.

Against that i absolutely cannot function on T4 alone, and feel unwell if the dose is increased significantly beyond the proportion that works.

ian

[Karlos]

Thanks all, the comments are much appreciated.

I was on 125mcg of levo, and didn't feel much benefit.

I have now switched to 100mcg Levo and 5mcg of T3 for starters.