I have recently been diagnosed with Hashimoto's and after a month on 25 mcg of Levo my GP has increased it to 50mcg. Still have 'off the scale' thyroid Peroxidase antibodies ( above measurable range in the thousands somewhere) but I wondered if others have experienced upper back pain without an alternative explanation? It is mid thoracic ( approx level of a bra strap) radiates into shoulder and is agony when I lay down. It puts me in the awful situation of being profoundly tired but forced to sit up, even during the night. Any ideas?