Triphala update: Unfortunately I have had to... - IBS Network

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Triphala update

Mutleyforever profile image
8 Replies

Unfortunately I have had to ( temporarily I hope ) stop Triphala. I had been experiencing venous pain behind my left knee for a couple of weeks, it affected me badly when walking and even if I rested. Initially I did not connect the two, but since I had stopped everything else, I had to stop it to see if that was the culprit…….It was, anyway I have decided to concentrate on upping my acid levels, to help my digestion with apple cider vinegar twice a day, and so far, so good.

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Mutleyforever profile image
Mutleyforever
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8 Replies
Meleber profile image
Meleber

It's always trial and error when looking for something that could help to alleviate our symptoms. Good to know that you probably did find the cause of the pain but unfortunately for you it seems to be related to Triphala. Cascara Sagrada or senna could also be options to try, if you haven't tried them before already. I've had good experiences with cascara in the past for alleviating my IBS C symptoms. Now on a trial with prucalopride and using a mix of bisacodyl / triphala / cascara as additional laxatives in the startup phase. My bowels didn't react 'immediately' and that's why I need to take 'rescue' medication too. My trial with prucalopride is for a month so will end the 1st of December.

PS Maybe you could find a Ayurvedic practitioner to ask why you had an adverse reaction 🤔

"Conclusions The results of the in vitro study suggest the propensity of gallic and ellagic acid to inhibit hepatic metabolism of the co-administered herbal products or drugs by human CYP450 enzymes, particularly CYP1A2, CYP2C9 and CYP2C19. The induction study in rats showed the potential inducing effect of Triphala formulation on CYP1A2. Until the correlation between plasma concentrations of gallic acid/ellagic acid and clinical relevance drug interaction has been confirmed, caution should be exercised when administering Triphala formulation with drugs with narrow therapeutic index values such as warfarin, cyclosporine and digoxin, as well as in patients with impaired hepatic function."

Source: "Potential Inhibitory and Inducing Effects of Triphala Formulation on Cytochrome P450 Enzymes" tis.wu.ac.th/index.php/tis/...

Mutleyforever profile image
Mutleyforever in reply toMeleber

Thanks Meleber, my slow transit does not need treatment now, I don’t need to take any medication but know that I am still dysfunctional, with visceral pain etc. I’m pretty sure I have low stomach acid that is behind all this ( quite common due to ageing and stress) , and also a trigger for ibs but completely overlooked by medics. Anyway I’m back on Apple cider vinegar, and maybe herbal bitters, ….see how that goes 😊

janetmtt profile image
janetmtt

oh that is a shame wonder why it did that - anyone know the reason why

Mutleyforever profile image
Mutleyforever in reply tojanetmtt

Hi, yes I was surprised but it does affect blood flow , maybe lowering blood pressure, usually good things, but if you have pre existing conditions it can interfere, which seems to have occurred 👎

xjrs profile image
xjrs

This is what I found on Triphala side effects, but it doesn't mention your experience, though may be some indirect cause:

onlymyhealth.com/side-effec...

Just goes to show that even natural products can have side effects like medicines do and need to be treated with an element of caution. As with many things you won't know until you try and everyone is different.

Mutleyforever profile image
Mutleyforever in reply toxjrs

Oh yes, herbal remedies can be powerful, not to be taken lightly, that is why I try one thing at a time when it is a new addition!

xjrs profile image
xjrs in reply toMutleyforever

Great approach 👍🙂.

janetmtt profile image
janetmtt

Such a shame as I am thinking of trying it and looking at the blurb it does say it reduces inflammation and can help joint pain etc. Could it have been a kind of detox on you - is it worth trying it again

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