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Xofigo
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Change in plans - looks like neuroendocrine
From my last post, I had an allergic reaction 15 minutes into my first dose of Docetaxel - part of a clinical trial combining Docetaxel and
Xofigo
(Radium-223).
From my last post, I had an allergic reaction 15 minutes into my first dose of Docetaxel - part of a clinical trial combining Docetaxel and
Xofigo
(Radium-223).
TonyS58
in
Advanced Prostate Cancer
3 years ago
Cabazitaxel dosage & frequency?
. ; stopped & began
Xofigo
for three cycles with a PSA at least doubling 2 of 3 months & pain & mets spreading, as per MRI; suspended
Xofigo
; in one month PSA jumped from 46 to 144 ; about to begin Cabazitaxel.
. ; stopped & began
Xofigo
for three cycles with a PSA at least doubling 2 of 3 months & pain & mets spreading, as per MRI; suspended
Xofigo
; in one month PSA jumped from 46 to 144 ; about to begin Cabazitaxel.
baltha
in
Advanced Prostate Cancer
3 years ago
Failed Chemo 101
While this is disappointing, I will continue with
Xofigo
(Radium 223) as soon as it clears insurance. What is the likelihood that I wiped out the entire class of taxanes by having reactions to Docetaxel? I'm sure that before long, I will need chemo for non-bone tumors, and I'm looking at options.
While this is disappointing, I will continue with
Xofigo
(Radium 223) as soon as it clears insurance. What is the likelihood that I wiped out the entire class of taxanes by having reactions to Docetaxel? I'm sure that before long, I will need chemo for non-bone tumors, and I'm looking at options.
TonyS58
in
Advanced Prostate Cancer
3 years ago
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Lu-177 switch from Xofigo. How long an interval?
The nuclear medicine physician administering the
Xofigo
said I should wait six months to get the
Xofigo
out of my system before beginning another radio pharmaceutical (therefore Lu-177.) Is this true or just one opinion?
The nuclear medicine physician administering the
Xofigo
said I should wait six months to get the
Xofigo
out of my system before beginning another radio pharmaceutical (therefore Lu-177.) Is this true or just one opinion?
baltha
in
Advanced Prostate Cancer
3 years ago
What to do next?
My Pop had a Axumin Pet Scan earlier this week, and was supposed to have his second
Xofigo
injection which was cancelled because of results/progression. Impression shows lung nodules, which demonstrate mild radiotracer uptake which are new and concerning for lung involvement.
My Pop had a Axumin Pet Scan earlier this week, and was supposed to have his second
Xofigo
injection which was cancelled because of results/progression. Impression shows lung nodules, which demonstrate mild radiotracer uptake which are new and concerning for lung involvement.
GoNapoli
in
Advanced Prostate Cancer
3 years ago
Long delay getting new therapy
My MO and I talked a couple of weeks ago and suspended
Xofigo
due to monthly doubling PSA and the MO promised a decision on new therapy but "I need a little time". After 2 weeks of not hearing back, I grow worried.
My MO and I talked a couple of weeks ago and suspended
Xofigo
due to monthly doubling PSA and the MO promised a decision on new therapy but "I need a little time". After 2 weeks of not hearing back, I grow worried.
baltha
in
Advanced Prostate Cancer
3 years ago
XOFIGO Update
I received my lab results back in preparation for round 2 of
Xofigo
on Friday. My white blood cell count was low, down to 2.2, taking a booster shot tomorrow to address that issue. The Alkaline Photophase is down to 75 and back in the normal range for the first time since before DX.
I received my lab results back in preparation for round 2 of
Xofigo
on Friday. My white blood cell count was low, down to 2.2, taking a booster shot tomorrow to address that issue. The Alkaline Photophase is down to 75 and back in the normal range for the first time since before DX.
BigTex3
in
Advanced Prostate Cancer
3 years ago
Xofigo experiences
In between treatments my Dad starts with pain in some areas, so I know it is probably progression does
Xofigo
alleviate pain for QOL?
In between treatments my Dad starts with pain in some areas, so I know it is probably progression does
Xofigo
alleviate pain for QOL?
GoNapoli
in
Advanced Prostate Cancer
3 years ago
Info on Xofigo
He is interested in
Xofigo
because of lower side effects. Thanks in advance.
He is interested in
Xofigo
because of lower side effects. Thanks in advance.
Yorkielover2
in
Advanced Prostate Cancer
3 years ago
What next after chemo, neuroendocrine cancer
Started
Xofigo
in early May. My question is, what next after
xofigo
? Genetic testing indicates lutetium not likely to be successful.
Started
Xofigo
in early May. My question is, what next after
xofigo
? Genetic testing indicates lutetium not likely to be successful.
Neuroendo
in
Advanced Prostate Cancer
3 years ago
Very important to ALWAYS use a bone-strengthening agent with Xofigo
I added a section to my article on
Xofigo
, highlighting the results of the REASSURE trial.
I added a section to my article on
Xofigo
, highlighting the results of the REASSURE trial.
Tall_Allen
in
Advanced Prostate Cancer
3 years ago
Off label use of Mekinist (Trametinib)
Xofigo
started in Feb 2014. Became anemic and could only be kept alive with monthly blood transfusions.
Xofigo
stopped in August. PSA over 120. Bills chance of living another 6 months bleak. Started Mekinist. Bill purchased it at $10,000 per month. By December 2014 PSA had dropped to 18.
Xofigo
started in Feb 2014. Became anemic and could only be kept alive with monthly blood transfusions.
Xofigo
stopped in August. PSA over 120. Bills chance of living another 6 months bleak. Started Mekinist. Bill purchased it at $10,000 per month. By December 2014 PSA had dropped to 18.
Graham49
in
Advanced Prostate Cancer
3 years ago
Xofigo what are side effects?
Looking for feed back on
Xofigo
treatment! Been on Lupron & Exgeva. Zytiga with Predisone added after two years. PSA rising last several month now over 300! looking to treat with least side effects! Quality of life Diagnosis was 12/2016 PSA over 1,000. PSA has never gone below 40
Looking for feed back on
Xofigo
treatment! Been on Lupron & Exgeva. Zytiga with Predisone added after two years. PSA rising last several month now over 300! looking to treat with least side effects! Quality of life Diagnosis was 12/2016 PSA over 1,000. PSA has never gone below 40
Yorkielover2
in
Advanced Prostate Cancer
3 years ago
Xofigo starting soon
Good morning everyone What has been your experiences with
Xofigo
. I’m currently taking Xtandi and Zoladex will add 6 treatments of
Xofigo
starting this week. I appreciate your thoughts. I only have Mets in the bones, but a lot of them.
Good morning everyone What has been your experiences with
Xofigo
. I’m currently taking Xtandi and Zoladex will add 6 treatments of
Xofigo
starting this week. I appreciate your thoughts. I only have Mets in the bones, but a lot of them.
BigTex3
in
Advanced Prostate Cancer
3 years ago
Latest from BATman Denmeade
These include BAT in combination with the immunotherapy Nivolumab (Opdivo) (NCT03554317), the DNA-repair inhibitor olaparib (Lynparza) (NCT03516812), the bone targeted radiation therapy 223Radium (
Xofigo
) (NCT04704505), and the DNA-damaging drug carboplatin (NCT03522064). 3 CONCLUSIONS The key findings
These include BAT in combination with the immunotherapy Nivolumab (Opdivo) (NCT03554317), the DNA-repair inhibitor olaparib (Lynparza) (NCT03516812), the bone targeted radiation therapy 223Radium (
Xofigo
) (NCT04704505), and the DNA-damaging drug carboplatin (NCT03522064). 3 CONCLUSIONS The key findings
pjoshea13
in
Advanced Prostate Cancer
2 years ago
Xofigo - first injection
My father received his first
Xofigo
treatment today. So far so good - with the exception of fatigue, he seems ok. What should we expect in the next few days? Should he be in something else while taking
Xofigo
? He is due for lupron in May and Xgeva in about a month or so. Thank you
My father received his first
Xofigo
treatment today. So far so good - with the exception of fatigue, he seems ok. What should we expect in the next few days? Should he be in something else while taking
Xofigo
? He is due for lupron in May and Xgeva in about a month or so. Thank you
ahjab
in
Advanced Prostate Cancer
3 years ago
Radium-223 & Fracture Risk
-Patrick Notes. mCRPC = metastatic castration-resistant prostate cancer Radium-223 =
Xofigo
(previously Alpharadin) [1] https://pubmed.ncbi.nlm.nih.gov/33958296/ Clin Genitourin Cancer . 2021 Apr 4;S1558-7673(21)00083-5. doi: 10.1016/j.clgc.2021.03.020. Online ahead of print.
-Patrick Notes. mCRPC = metastatic castration-resistant prostate cancer Radium-223 =
Xofigo
(previously Alpharadin) [1] https://pubmed.ncbi.nlm.nih.gov/33958296/ Clin Genitourin Cancer . 2021 Apr 4;S1558-7673(21)00083-5. doi: 10.1016/j.clgc.2021.03.020. Online ahead of print.
pjoshea13
in
Advanced Prostate Cancer
3 years ago
First major pathological fracture
We’ve done Docetaxel (3 rounds, stopped due to pulmonary edema and PCP pneumonia), Zytiga, Xtandi,
Xofigo
, and Lynparza . Dr would like him to try Cabazitaxel but husband is not sure given his bad experience with Docetaxel. Dr also considering provenge.
We’ve done Docetaxel (3 rounds, stopped due to pulmonary edema and PCP pneumonia), Zytiga, Xtandi,
Xofigo
, and Lynparza . Dr would like him to try Cabazitaxel but husband is not sure given his bad experience with Docetaxel. Dr also considering provenge.
WVtwinsmama
in
Advanced Prostate Cancer
3 years ago
Feeling dizzy
He will take his first dose of
Xofigo
next week. Overall he feels good, no major pain, he eats ok but every once in a while he gets dizzy. Is there anything I could get him to help with the dizziness? Thank you.
He will take his first dose of
Xofigo
next week. Overall he feels good, no major pain, he eats ok but every once in a while he gets dizzy. Is there anything I could get him to help with the dizziness? Thank you.
ahjab
in
Advanced Prostate Cancer
3 years ago
Metastasis Directed Therapy (MDT) is here to stay for Oligometastatic Patients !!! Part(1) SABR/SBRT
I believe we will see more trials involving combo therapy--Systemic therapy with SBRT and
Xofigo
is currently on trial at City of Hope. The RAVENS trial with SBRT and
Xofigo
is ongoing and expect some interim data in 2022.
I believe we will see more trials involving combo therapy--Systemic therapy with SBRT and
Xofigo
is currently on trial at City of Hope. The RAVENS trial with SBRT and
Xofigo
is ongoing and expect some interim data in 2022.
NPfisherman
in
Fight Prostate Cancer
3 years ago
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