Experiences with

Sorafenib

just started a course of sorafenIb. 2 x 200mg tabs once a day. Any comments or side effects to report. All the best.

I read it can be harsh like the original target therapy med Sorafenib. Anyone experience radio frequency ablation? What was recovery like? Successful on neutralizing tumor growth? I look forward to hearing actual people’s experiences with treatment and HCC, Be well, Cheers

https://www.sciencedirect.com/science/article/abs/pii/S1043661822000858 

: it has been well-known that sorafenib produces anticancer effects through targeting multiple kinases, but it was shown recently that it has “off-target” 5-HTR binding activity.

AFP started increasing with no correlation on scans, added Sorafenib to Opdivo at half dose as couldn't tolerate full and AFP kept increasing to over 600 though minimal change in scans.

Have you been diagnosed with HCC and are currently on oral systemic therapy drug treatment for liver cancer (for example, sorafenib, regorafenib, nivolumab, lenvatinib, pembrolizumab, or cabozantinib)? If so, we’d like to ask for your help.

Approved Sorafenib (also first level treatment?) which MD is combining with continued Opdivo. Question re first level treatment and insurance companies as this is a new treatment that wasn't available before. Has anyone else run into insurance denials?

My father, 64 years old, diagnosed with HCC 18 months ago and underwent TACE 3 times. HCC was stable and he was doing fine. Since a month, he started coughing regularly and the plain CT yesterday showed multiple nodules in the lungs. But he doesn't have any pain in the chest region. Although plain CT

Results: The drug candidates of sorafenib, olaparib, elesclomol, tanespimycin, and ponatinib were predicted to be active for the treatment of CRPC.

I’m now being treated by the Oncology service and will be starting on initial dose( 200mg po bid) of Sorafenib on 3 June. Any tips on dealing w/ side effects?

So Sorafenib is the recommended treatment now. For some unknown reason the biopsy was delayed until end of October but unti that was done he could start treatment. We went to Kings on Monday to see the consultant, discuss the biopsy results and agree treatment plan.

My brother has been taking Sorafenib chemo tablet for 2 weeks now but has had to stop because it's made him lose a considerable amount of weight, has become dehydrated and also has incontinence. He says he has lost the ability to walk which really worries me.

I went to see the oncologist yday and he said the only treatment is sorafenib. Nothing else they could offer or do(including trails). I am devastated as i have gone from a cure to basically a terminal diagnosis in the space of a few months. Is sorafanib any good??

I went to see the oncologist yday and he said the only treatment is sorafenib. Nothing else they could offer or do(including trails). I am devastated as i have gone from a cure to basically a terminal diagnosis in the space of a few months. Is sorafanib any good??

I was started on Sorafenib and took for 1 month which made me very sick. Started Nivolumab Nov. 8. After 8 Nivolumab 240mg treatments, CT was done on Feb. 27, 2018. CT showed shrinkage of the tumor to 4.8cm x 6.0cm. My AFP was 3.2. A month later the AFP is 2.1.

Anyone been on Nexavar treatment just started taking them Wednesday 400mg to start with , my third tace treatment didn’t really work, I’ve got liver cancer hepatocellular cancinoma , feeling every nervous about it all .

My AFP increases when I reduce the dose of sorafenib because of side effects e.g. skin blisters, painful round swelling of palm and sole,sore tongue, mouth etc.But some times after healing of skin and other problems I start start full dose then again side effects reappears and AFP comes down.

., sorafenib) destroys cancer cells and stops the production of new cancer cells by using a variety of chemicals. Chemotherapy may be administered by mouth or through the vein; the drug(s) interrupts the life cycle of cells by stopping them from growing/reproducing.

The only known therapy for patients with advanced HCC was sorafenib, but there's a new treatment named Opdivo. Its effectiveness was proven when a study showed major disease stability in multiple testing areas. Learn more here: http://bit.ly/2frP0um

hepatologist yesterday who said that because my husband had a kidney tumour nothing to do with liver which was successfully ablated 3 years ago and he had a heart attack resulting in stent being put in this was december 2015 and because he has ascites he said he wouldnt recommend ablation but suggested sorafenib