Experiences with

Riluzole

[u]However grim the findings, the team’s study resulted in some positive news: ALS drug , diabetes drug metformin, and cancer drug imatinib appear to prevent the aforementioned type of neurons from becoming infected with COVID and, thus, losing their ability to function properly[/u]."

This category of drugs includes riluzole, lamotrigine, and lifarizine, which are sodium channel blockers. Attempts have also been made to affect the various sites of the coupled glutamate receptor itself. Some of these drugs include felbamate, ifenprodil, magnesium, memantine, and nitroglycerin.

Non-specific pharmacological agents of potential benefit include amantadine, alpha-lipoic acid, buspirone, branchedchain amino acids, creatine, coenzyme Q10, vitamin E, physostigmine, riluzole, and selective serotonin reuptake inhibitors.

Hi Ataxia Friends I recently saw my neurologist and he suggested trying Riluzole, a drug in trial for ALS- Lou Gehrig disease. I have SCA6. Has anyone tried this for ataxia? Thanks Tina

Non-specific pharmacological agents of potential benefit include amantadine, alpha-lipoic acid, buspirone, branchedchain amino acids, creatine, coenzyme Q10, vitamin E, physostigmine, riluzole, and selective serotonin reuptake inhibitors.

Has anyone tried Riluzole? This medicine has passed phase III clinical trial. https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(15)00201-X/fulltext Only that it seems a little expensive.

Spinocerebellar Ataxia Type 3 Antisense RNAi Oligonucleotide to Inhibit Ataxin-1 for Spinocerebellar Ataxia Antisense RNAi Oligonucleotide to Inhibit Ataxin-7 for Spinocerebellar Ataxia Type 7 - ASO-7 BHV-4157 CAD-1883 epoetin alfa INT-41 Oligonucleotides to Inhibit ATXN3 for Spinocerebellar Ataxia Type 3 riluzole

"Riluzole (marketed as Rilutek and Teglutik) is a drug used to treat amyotrophic lateral sclerosis." [2] Riluzole "downregulates AR-FL, mutant ARs, and AR-V7 proteins expression by protein degradation".

https://prostatecancernewstoday.com/tag/amyotrophic-lateral-sclerosis/

Hi Has anyone been prescribed Riluzole for cerebellar ataxia?

Hi Has anyone had any positive effects from taking riluzole? I have read that it stops the ataxia symptoms worsening. I know there is a trial in USA at the moment. Does anyone know how this is going? Thanks

and he mentioned the drug Riluzole to me. He said it has been used for Motor Neurone Disease but that it may help with FA too. Has anyone else heard of it or been prescribed it?

//www.intechopen.com/books/a-synopsis-of-parkinson-s-disease/melatonin-in-parkinson-s-disease Acetyl-L-carnitine Aspirin (acetylsalicylic acid) Carnitine Caffeine Creatine Curcumin (–)-Epigallocatechin gallate (EGCG) (R)-Lipoic acid Melatonin MLT) (–)-Nicotine Nicotinamide Resveratrol Riluzole

There is not enough evidence for or against the following to slow the progression of Parkinson disease: • Riluzole: This is a drug used to slow the progress of amyotrophic lateral sclerosis (ALS or Lou Gehrig’s disease). • Coenzyme Q10: This is a vitamin-like substance found in a variety of foods and