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Local treatment & metastatic prostate cancer
"Previous radical
prostatectomy
in patients with metastatic prostate cancer was associated with a statistically significant decrease in the risk of death (hazard ratio 0.77 ...) relative to those who did not undergo earlier
prostatectomy
. " In the new papers: [1] (2016 - Italy) "Not all patients with
"Previous radical
prostatectomy
in patients with metastatic prostate cancer was associated with a statistically significant decrease in the risk of death (hazard ratio 0.77 ...) relative to those who did not undergo earlier
prostatectomy
. " In the new papers: [1] (2016 - Italy) "Not all patients with
pjoshea13
in
Advanced Prostate Cancer
8 years ago
Surgery v. Radiation - Survival
"Treatment with RP {radical
prostatectomy
} in 4459 men, EBRT {external-beam radiation therapy} in 1261 men, or BT {brachytherapy} in 972 men."
"Treatment with RP {radical
prostatectomy
} in 4459 men, EBRT {external-beam radiation therapy} in 1261 men, or BT {brachytherapy} in 972 men."
pjoshea13
in
Prostate Cancer Network
8 years ago
Foods/Supplements-Vitamins: Beef
"The study population consisted of 268 African-American and Caucasian men who underwent radical
prostatectomy
for prostate cancer."
"The study population consisted of 268 African-American and Caucasian men who underwent radical
prostatectomy
for prostate cancer."
pjoshea13
in
Advanced Prostate Cancer
8 years ago
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Had a
prostatectomy
in April 2011 (Gleason 3+4). PSA was non-detectable until December 2014 when it went up to .4. Did salvage radiation in February 2015 and my PSA was very low until February 2016 when it went to 1.
Had a
prostatectomy
in April 2011 (Gleason 3+4). PSA was non-detectable until December 2014 when it went up to .4. Did salvage radiation in February 2015 and my PSA was very low until February 2016 when it went to 1.
Pwjpp55
in
Advanced Prostate Cancer
8 years ago
Cholesterol - squalene monooxygenase (SQLE)
SQLE expression at cancer diagnosis is prognostic for lethal prostate cancer both after curative-intent
prostatectomy
and in a watchful waiting setting, possibly by facilitating micrometastatic disease. Copyright ©2016, American Association for Cancer Research.
SQLE expression at cancer diagnosis is prognostic for lethal prostate cancer both after curative-intent
prostatectomy
and in a watchful waiting setting, possibly by facilitating micrometastatic disease. Copyright ©2016, American Association for Cancer Research.
pjoshea13
in
Advanced Prostate Cancer
8 years ago
Biopsies While On Active Surveillance Do Not Have A Negative Affect On Sexual And Urinary Functioning Post Surgery
This finding should provide some reassurance with respect to early functional outcomes after radical having a radical
prostatectomy
. However, we still need to remember that the biopsy itself does come with some inherent risk for infection. http://tinyurl.com/zr3fhro Joel
This finding should provide some reassurance with respect to early functional outcomes after radical having a radical
prostatectomy
. However, we still need to remember that the biopsy itself does come with some inherent risk for infection. http://tinyurl.com/zr3fhro Joel
JoelT
in
Prostate Cancer Network
8 years ago
4 month Casodex + radiation
At the age of 49 in October of 2013, I had a
prostatectomy
with 23 nodes taken. I am a gleason 4+5, SVI in both sv's, epe, negative margins, LN0. Decipher test results 25%. I belong to the club I never wanted to join of high risk locally advanced Pca.
At the age of 49 in October of 2013, I had a
prostatectomy
with 23 nodes taken. I am a gleason 4+5, SVI in both sv's, epe, negative margins, LN0. Decipher test results 25%. I belong to the club I never wanted to join of high risk locally advanced Pca.
bitittle
in
Advanced Prostate Cancer
8 years ago
Foods/Supplements-Vitamins: Capsaicin - Cayenne
Full study title: "CAPSAICIN Trial: A Prospective Study of Capsaicin in Subjects With Clinically Localized Prostate Cancer Undergoing Active Surveillance or Radical
Prostatectomy
".
Full study title: "CAPSAICIN Trial: A Prospective Study of Capsaicin in Subjects With Clinically Localized Prostate Cancer Undergoing Active Surveillance or Radical
Prostatectomy
".
pjoshea13
in
Advanced Prostate Cancer
8 years ago
In 2016 I joined this ADV Prostate Cancer club. My forward path is dark, uncertain, and full of fear. I seek info on what to expect.
Surgeon recommended a robotic
prostatectomy
to remove my prostate. Unfortunately, when I came in for a post surgical follow-up, I still had PSA of 3.5 & 3.6 on two different measurements. Some of the prostate cancer slipped by. Pathology on 5 nodes were positive.
Surgeon recommended a robotic
prostatectomy
to remove my prostate. Unfortunately, when I came in for a post surgical follow-up, I still had PSA of 3.5 & 3.6 on two different measurements. Some of the prostate cancer slipped by. Pathology on 5 nodes were positive.
SailorDavid
in
Advanced Prostate Cancer
8 years ago
Foods/Supplements-Vitamins: Vitamin A (Retinol, Retinoic Acid [RA], Beta Carotene)
[B1d] (2002 - US) Normal prostate cells metabolize retinol via the LRAT enzyme. "... we analyzed LRAT protein expression in tissue sections from six
prostatectomy
specimens by immunohistochemistry.
[B1d] (2002 - US) Normal prostate cells metabolize retinol via the LRAT enzyme. "... we analyzed LRAT protein expression in tissue sections from six
prostatectomy
specimens by immunohistochemistry.
pjoshea13
in
Advanced Prostate Cancer
8 years ago
Post Surgery Update...
So, I'm 3 months out of surgery (radical retropubic
prostatectomy
), and just received my first evaluation of my most recent blood draw...to bring everyone up to speed with my specifics, 56 year old, no family history of any kind of cancer, excellent state of general health and physical condition (152
So, I'm 3 months out of surgery (radical retropubic
prostatectomy
), and just received my first evaluation of my most recent blood draw...to bring everyone up to speed with my specifics, 56 year old, no family history of any kind of cancer, excellent state of general health and physical condition (152
dtr1960
in
Fight Prostate Cancer
8 years ago
Radiotherapy?
My PSA has gone up and down for a couple of years. 12 samples were taken for the biopsy, 7 of 12 positive T2b. urologist recommended Radical retropubic
prostatectomy
and mentioned radiotherapy. I have searched the net and found some good information and some contradictory.
My PSA has gone up and down for a couple of years. 12 samples were taken for the biopsy, 7 of 12 positive T2b. urologist recommended Radical retropubic
prostatectomy
and mentioned radiotherapy. I have searched the net and found some good information and some contradictory.
Hidden
in
Prostate Cancer Network
8 years ago
Surgery or Radiation?
Hi Guys, I'm looking for some wisdom from my learned brothers. The Urologist who diagnosed me (April 19th) told me that my PC was advanced and I had 'positive margins' which I understand to mean that there is evidence the cancer in my prostate was evident at the very end of at least some of my biopsy
Hi Guys, I'm looking for some wisdom from my learned brothers. The Urologist who diagnosed me (April 19th) told me that my PC was advanced and I had 'positive margins' which I understand to mean that there is evidence the cancer in my prostate was evident at the very end of at least some of my biopsy
paulofaus
in
Advanced Prostate Cancer
8 years ago
mTOR
[T10] Rapamycin in men prior to
prostatectomy
. "At 3 mg daily, rapamycin successfully and safely inhibited prostate cancer S6 phosphorylation and achieved relatively high prostate tissue concentrations. No effect on AKT phosphorylation, tumor proliferation, or apoptosis was observed." etc.
[T10] Rapamycin in men prior to
prostatectomy
. "At 3 mg daily, rapamycin successfully and safely inhibited prostate cancer S6 phosphorylation and achieved relatively high prostate tissue concentrations. No effect on AKT phosphorylation, tumor proliferation, or apoptosis was observed." etc.
pjoshea13
in
Advanced Prostate Cancer
8 years ago
Gleason Grades 3+3 vs. 3+4 And The Decision To Use Active Surveillance As A Primary Treatment
The presence of Gleason 3 + 4 at biopsy, when compared to 3 + 3, increases the risk of adverse pathology being present at radical
prostatectomy
.
The presence of Gleason 3 + 4 at biopsy, when compared to 3 + 3, increases the risk of adverse pathology being present at radical
prostatectomy
.
JoelT
in
Prostate Cancer Network
8 years ago
Biochemical Recurrence
I'm 14 years since my initial radical
prostatectomy
. PSA levels have been rising for 3 years. My question is at what point should my Urologist suggest for me to see oncologist? I'm not putting numbers, I've read so many conflicting suggestions online.
I'm 14 years since my initial radical
prostatectomy
. PSA levels have been rising for 3 years. My question is at what point should my Urologist suggest for me to see oncologist? I'm not putting numbers, I've read so many conflicting suggestions online.
cajun1949
in
Advanced Prostate Cancer
8 years ago
Perioperative Blood Transfusion as a Significant Predictor of Biochemical Recurrence and Survival after Radical Prostatectomy in Patients wi
In preparation for my radical
prostatectomy
12 years ago, I had two units of blood drawn (the maximum I was allowed), in case blood was needed during surgery. The surgeon told me that most RPs did not require blood. In any case, 2 units would be more than enough.
In preparation for my radical
prostatectomy
12 years ago, I had two units of blood drawn (the maximum I was allowed), in case blood was needed during surgery. The surgeon told me that most RPs did not require blood. In any case, 2 units would be more than enough.
pjoshea13
in
Prostate Cancer Network
8 years ago
23 years post-diagnosis
He underwent radical
prostatectomy
. In 2001 his PSA started to go up and reached 4.4. Bone scan did not show any mets. He underwent radiation for two months and his PSA went to .10. He was also on Lupron for several months. In spring 2012 PSA rose to 4.4 and started to climb.
He underwent radical
prostatectomy
. In 2001 his PSA started to go up and reached 4.4. Bone scan did not show any mets. He underwent radiation for two months and his PSA went to .10. He was also on Lupron for several months. In spring 2012 PSA rose to 4.4 and started to climb.
4myhusband
in
Advanced Prostate Cancer
8 years ago
Had surgery, had radiation. Am now on ADT successfully!
Gleason Estimate 8-10; DaVinci Robotically-assisted laparoscopic radical
prostatectomy
(RALRP) w/ lymph node dissection; Dx: Stage III prostate cancer; T3b - Tumor (70% of prostate) with positive margins into seminal vesicles. GS 10 (5 + 5). Lymph node: negative N0.
Gleason Estimate 8-10; DaVinci Robotically-assisted laparoscopic radical
prostatectomy
(RALRP) w/ lymph node dissection; Dx: Stage III prostate cancer; T3b - Tumor (70% of prostate) with positive margins into seminal vesicles. GS 10 (5 + 5). Lymph node: negative N0.
Pguenette
in
Advanced Prostate Cancer
8 years ago
Semen
I don't know just how personal I can get here, but.....my seminal vesicles were supposedly taken during my radical
prostatectomy
, but when I "induce" an orgasm, I appear to leak seminal fluid. Any ideas? I apologize if it's TMI.
I don't know just how personal I can get here, but.....my seminal vesicles were supposedly taken during my radical
prostatectomy
, but when I "induce" an orgasm, I appear to leak seminal fluid. Any ideas? I apologize if it's TMI.
Ernie_Aguilar
in
Advanced Prostate Cancer
8 years ago
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