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Duke "CHAMP" trial update
carboplatin, cabazitaxel,
nivolumab
and ipilimumab combined to slow advanced prostate cancer? Answer: We don't know yet. My PSA numbers have dropped significantly, but I'm very advanced so they dance around a bit. Lower overall but they jump back up at times.
carboplatin, cabazitaxel,
nivolumab
and ipilimumab combined to slow advanced prostate cancer? Answer: We don't know yet. My PSA numbers have dropped significantly, but I'm very advanced so they dance around a bit. Lower overall but they jump back up at times.
HerbieP
in
Advanced Prostate Cancer
2 years ago
Neuroendocrine Prostate Cancer [NEPC]
Tumor Mutational Burden and Efficacy of
Nivolumab
Monotherapy and in Combination with Ipilimumab in Small-Cell Lung Cancer. Cancer Cell 2019;35:329. [Crossref] [PubMed] Isaacsson Velho P, Antonarakis ES. PD-1/PD-L1 pathway inhibitors in advanced prostate cancer.
Tumor Mutational Burden and Efficacy of
Nivolumab
Monotherapy and in Combination with Ipilimumab in Small-Cell Lung Cancer. Cancer Cell 2019;35:329. [Crossref] [PubMed] Isaacsson Velho P, Antonarakis ES. PD-1/PD-L1 pathway inhibitors in advanced prostate cancer.
pjoshea13
in
Advanced Prostate Cancer
2 years ago
COMBAT-CRPC: COncurrent adMinistration of Bipolar Androgen Therapy and Nivolumab in men with mCRPC
Markowski concluded his presentation of this phase 2 trial assessing BAT plus
nivolumab
with the following take-home points: BAT plus
nivolumab
was well-tolerated without concerning safety signals The combination met the pre-specified primary endpoint of confirmed PSA50response in a heavily treated population
Markowski concluded his presentation of this phase 2 trial assessing BAT plus
nivolumab
with the following take-home points: BAT plus
nivolumab
was well-tolerated without concerning safety signals The combination met the pre-specified primary endpoint of confirmed PSA50response in a heavily treated population
pjoshea13
in
Advanced Prostate Cancer
3 years ago
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Nivolumab
I am looking into a clinical trial with
Nivolumab
in treating Pc? Does anyone have any experience or information about this? My Google searches have limited results.
I am looking into a clinical trial with
Nivolumab
in treating Pc? Does anyone have any experience or information about this? My Google searches have limited results.
rembrothers
in
Advanced Prostate Cancer
3 years ago
Good morning sir!
It's a hellava long infusion, premeds,
nivolumab
, ipilimumab, cabazitaxel, and carboplatin - with gaps in between for observation. I had no odd side effects besides a brief 1 minute flush feeling on the back of my neck. Total 7 hours.
It's a hellava long infusion, premeds,
nivolumab
, ipilimumab, cabazitaxel, and carboplatin - with gaps in between for observation. I had no odd side effects besides a brief 1 minute flush feeling on the back of my neck. Total 7 hours.
HerbieP
in
Advanced Prostate Cancer
3 years ago
Priority review of relatimab plus nivo
September 20, 2021 FDA grants priority review to relatlimab-
nivolumab
regimen for advanced melanoma Does anyone know what this “priority review” means in regards to when this combination would become available to patients ? Thanks
September 20, 2021 FDA grants priority review to relatlimab-
nivolumab
regimen for advanced melanoma Does anyone know what this “priority review” means in regards to when this combination would become available to patients ? Thanks
strawberryjam
in
Melanoma Caregivers
3 years ago
CHAMP Clinical Trial Time for this kid
Given my prostate has evolved to Gleason 10 and neuroendocrine (small cell) I'm in the process of qualifying for the CHAMP trial:
Nivolumab
, ipilimumab, cabazitaxel and carboplatin.
Given my prostate has evolved to Gleason 10 and neuroendocrine (small cell) I'm in the process of qualifying for the CHAMP trial:
Nivolumab
, ipilimumab, cabazitaxel and carboplatin.
HerbieP
in
Advanced Prostate Cancer
3 years ago
Out of Nivolumab/Opdivo Clinical Trial
My husband, Steve (Stevana on this site), is now out of the phase 2 clinical trial for the immunotherapy drug
Nivolumab
(a/k/a Opdivo). He started the trial in August, 2020 which also included infusions of Docetaxel.
My husband, Steve (Stevana on this site), is now out of the phase 2 clinical trial for the immunotherapy drug
Nivolumab
(a/k/a Opdivo). He started the trial in August, 2020 which also included infusions of Docetaxel.
Avanat
in
Advanced Prostate Cancer
3 years ago
Duke CHAMP clinical Trial Update
I've had my first infusion of the two chemos cabazitaxel and carboplatin and two immuno-therapies (
nivolumab
and ipilimumab) 14 days ago. My side effects have been less than what docetaxel were.
I've had my first infusion of the two chemos cabazitaxel and carboplatin and two immuno-therapies (
nivolumab
and ipilimumab) 14 days ago. My side effects have been less than what docetaxel were.
HerbieP
in
Advanced Prostate Cancer
3 years ago
ASCO presentations on melanoma research this week
The researchers found that the immunotherapy combination doubled the amount of time that the melanoma was stopped compared with giving
nivolumab
alone.
The researchers found that the immunotherapy combination doubled the amount of time that the melanoma was stopped compared with giving
nivolumab
alone.
missyrand
Ambassador
in
Melanoma Caregivers
3 years ago
Lymph node recurrence- immunotherapy
My specialist nurse said they want to start me on immunotherapy (
Nivolumab
). Does anyone have any experience of this or know how effective it is? Thanks Nicola
My specialist nurse said they want to start me on immunotherapy (
Nivolumab
). Does anyone have any experience of this or know how effective it is? Thanks Nicola
Da1sychain
in
Oesophageal & Gastric Cancer
3 years ago
Nivolumab + Ipilimumab for MCRPC
How are these drugs administered? Is a genetic component more reactive to this therapy. Does this show promise?
How are these drugs administered? Is a genetic component more reactive to this therapy. Does this show promise?
ronton2
in
Advanced Prostate Cancer
3 years ago
Mixed Results for Immunotherapy in Metastatic Prostate Cancer
"Ten of 35 (28.6%) patients responded to the combination of
nivolumab
(Opdivo) and ipilimumab (Yervoy). The activity fell short of the 40% threshold for a positive outcome but well above the historical response rate for immunotherapy in patients previously treated with docetaxel."
"Ten of 35 (28.6%) patients responded to the combination of
nivolumab
(Opdivo) and ipilimumab (Yervoy). The activity fell short of the 40% threshold for a positive outcome but well above the historical response rate for immunotherapy in patients previously treated with docetaxel."
snoraste
in
Advanced Prostate Cancer
3 years ago
Nivolumab effective treatment for malignant mesothelioma.
Nivolumab
monotherapy is an effective treatment option for relapsed malignant mesothelioma (MM), according to research presented today at the International Association for the Study of Lung Cancer World Conference on Lung Cancer.
Nivolumab
monotherapy is an effective treatment option for relapsed malignant mesothelioma (MM), according to research presented today at the International Association for the Study of Lung Cancer World Conference on Lung Cancer.
2greys
in
Lung Conditions Community Forum
3 years ago
What if your loved one could get access to free immunotherapy treatment using Nivolumab, also known as OPDIVO?
What if you could get access to free immunotherapy treatment using
Nivolumab
, also known as OPDIVO? Opdivo is used for other cancer types, but has not yet been approved for prostate cancer. Opdivo is a medicine that may treat certain cancers by working with your immune system.
What if you could get access to free immunotherapy treatment using
Nivolumab
, also known as OPDIVO? Opdivo is used for other cancer types, but has not yet been approved for prostate cancer. Opdivo is a medicine that may treat certain cancers by working with your immune system.
Darryl
Partner
in
Prostate Cancer Caregivers
3 years ago
What if you could get access to free immunotherapy treatment using Nivolumab, also known as OPDIVO?
What if you could get access to free immunotherapy treatment using
Nivolumab
, also known as OPDIVO? Opdivo is used for other cancer types, but has not yet been approved for prostate cancer. Opdivo is a medicine that may treat certain cancers by working with your immune system.
What if you could get access to free immunotherapy treatment using
Nivolumab
, also known as OPDIVO? Opdivo is used for other cancer types, but has not yet been approved for prostate cancer. Opdivo is a medicine that may treat certain cancers by working with your immune system.
Darryl
Partner
in
Prostate Cancer And Gay Men
3 years ago
Exclusive Fasttrak - Apply to clinical trial testing a new immunotherapy for prostate cancer!
What if you could get access to free immunotherapy treatment using
Nivolumab
, also known as OPDIVO? Opdivo is used for other cancer types, but has not yet been approved for prostate cancer. Opdivo is a medicine that may treat certain cancers by working with your immune system.
What if you could get access to free immunotherapy treatment using
Nivolumab
, also known as OPDIVO? Opdivo is used for other cancer types, but has not yet been approved for prostate cancer. Opdivo is a medicine that may treat certain cancers by working with your immune system.
Darryl
Partner
in
Advanced Prostate Cancer
3 years ago
Claim your spot in Immunotherapy Trial testing Opvido for prostate cancer. Hurry, please
Malecare, along with our partners, is prescreening our community for a study of Opvido (
Nivolumab
) or Placebo in Combination With Docetaxel in men With Advanced Castration-resistant Prostate Cancer. Using a novel prescreening method, applying through Malecare might Fastrack your application.
Malecare, along with our partners, is prescreening our community for a study of Opvido (
Nivolumab
) or Placebo in Combination With Docetaxel in men With Advanced Castration-resistant Prostate Cancer. Using a novel prescreening method, applying through Malecare might Fastrack your application.
Darryl
Partner
in
Advanced Prostate Cancer
3 years ago
Enter trial of Opvido (Nivolumab) or Placebo in Combination With Docetaxel in men With Advanced Castration-resistant Prostate Cancer- Hurry
Malecare, along with our partners, is prescreening our community for a study of Opvido (
Nivolumab
) or Placebo in Combination With Docetaxel in men With Advanced Castration-resistant Prostate Cancer. Using a novel prescreening method, applying through Malecare might Fastrack your application.
Malecare, along with our partners, is prescreening our community for a study of Opvido (
Nivolumab
) or Placebo in Combination With Docetaxel in men With Advanced Castration-resistant Prostate Cancer. Using a novel prescreening method, applying through Malecare might Fastrack your application.
Darryl
Partner
in
Advanced Prostate Cancer
3 years ago
Has anyone received the Covid-19 Vaccine while taking Immunotherapy?
Fellow cancer patients, I have been very concerned about how my immunotherapy (Opdivo/
nivolumab
) might affect my body’s response to the Covid-19 vaccine. During my past year on this treatment, my immune system has “overresponded” on several occasions as can be a side-effect of the treatment.
Fellow cancer patients, I have been very concerned about how my immunotherapy (Opdivo/
nivolumab
) might affect my body’s response to the Covid-19 vaccine. During my past year on this treatment, my immune system has “overresponded” on several occasions as can be a side-effect of the treatment.
Jenniferroseolson
in
Lung Cancer Support
3 years ago
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