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Experiences with
Gefitinib
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SD last CXR
57 years old female. Diagnosed S4 with brain secondaries Feb 18 treated with Gamma Knife and ceritinib. Pneumonia so now just going onto Pem maintenance. Initial partial response now SD. ROS 1
57 years old female. Diagnosed S4 with brain secondaries Feb 18 treated with Gamma Knife and ceritinib. Pneumonia so now just going onto Pem maintenance. Initial partial response now SD. ROS 1
Stouens
in
The Roy Castle Lung Cancer Foundation
6 years ago
Vitamin D
Hi All, I've been on
Gefitinib
for 19 months and been getting rather down of late with what I take to be the numerous side effects. OK, I fully agree it's better than the alternative!
Hi All, I've been on
Gefitinib
for 19 months and been getting rather down of late with what I take to be the numerous side effects. OK, I fully agree it's better than the alternative!
Neil-SueD
in
The Roy Castle Lung Cancer Foundation
6 years ago
Vitamin E - Tocotrienols
In addition, increasing lines of evidence has shown that tocotrienols can sensitize cancer cells to chemotherapeutic agents such as celecoxib, doxorubicin, erlotinib,
gefitinib
, gemcitabine, paclitaxel, statin etc.
In addition, increasing lines of evidence has shown that tocotrienols can sensitize cancer cells to chemotherapeutic agents such as celecoxib, doxorubicin, erlotinib,
gefitinib
, gemcitabine, paclitaxel, statin etc.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
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"A kiss of death for prostate cancer"
The drug
Gefitinib
is used to treat breast, lung, and other cancers by inhibiting epidermal growth factor receptor (EGFR) signaling, but it has only a limited effect on prostate cancer.
The drug
Gefitinib
is used to treat breast, lung, and other cancers by inhibiting epidermal growth factor receptor (EGFR) signaling, but it has only a limited effect on prostate cancer.
JLS1
in
Advanced Prostate Cancer
7 years ago
Changing from crizotinib to ceritinib
My husband is about to change from crizotinib to ceritinib and I was wondering if anyone else had done this. I would be grateful for any advice on side effects, effectiveness etc of ceritinib and how it compares to crizotinib. I’m hoping the changeover will be smooth especially with Christmas round
My husband is about to change from crizotinib to ceritinib and I was wondering if anyone else had done this. I would be grateful for any advice on side effects, effectiveness etc of ceritinib and how it compares to crizotinib. I’m hoping the changeover will be smooth especially with Christmas round
nannyjanny
in
The Roy Castle Lung Cancer Foundation
7 years ago
Paraneoplastic neuropathy?
My concern is that the
Gefitinib
is no longer working. I am due my next CT scan in about a month's time and will raise these concerns with the oncologist when I see them next week regarding the next monthly consultation and review of
Gefitinib
prescription renewal.
My concern is that the
Gefitinib
is no longer working. I am due my next CT scan in about a month's time and will raise these concerns with the oncologist when I see them next week regarding the next monthly consultation and review of
Gefitinib
prescription renewal.
Neil-SueD
in
The Roy Castle Lung Cancer Foundation
7 years ago
Positive news
It's been a roller coaster for the last 9 months due to the side effects of
Gefitinib
but this latest news is the reward. It's not a nice drug but it's doing it's job in his fight against the cancer. My husbands positive attitude right from the beginning has been fantastic too.
It's been a roller coaster for the last 9 months due to the side effects of
Gefitinib
but this latest news is the reward. It's not a nice drug but it's doing it's job in his fight against the cancer. My husbands positive attitude right from the beginning has been fantastic too.
CaroleH1949
in
The Roy Castle Lung Cancer Foundation
7 years ago
Gefitinib break. 2 new tumours
I have been taking
gefitinib
for 3 years. I recently had a 2 week break and then my oncologist reduced my does to every other day due to bad hand and foot syndrome. my latest scan shows 2 new tumours. My oncologist seems fairly certain that
gefitinib
is no longer working.
I have been taking
gefitinib
for 3 years. I recently had a 2 week break and then my oncologist reduced my does to every other day due to bad hand and foot syndrome. my latest scan shows 2 new tumours. My oncologist seems fairly certain that
gefitinib
is no longer working.
Readhill
in
The Roy Castle Lung Cancer Foundation
7 years ago
Hand and foot syndrome gefitinib
I think I may have hand and foot syndrome.....I am phoning my specialist nurse today....has anyone taking
gefitinib
experienced this. I am moisturing lot and trying to keep my feet cool and elevated as much as possible.
I think I may have hand and foot syndrome.....I am phoning my specialist nurse today....has anyone taking
gefitinib
experienced this. I am moisturing lot and trying to keep my feet cool and elevated as much as possible.
Readhill
in
The Roy Castle Lung Cancer Foundation
7 years ago
Tagrisso/Osimertinib side-effects?? Nails lifting???
Hi all - I have been fortunate to have been given Iressa/
Gefitinib
as first line treatment for stage 4 lung cancer. I had been on that almost 3 years when the cancer started to grow again.
Hi all - I have been fortunate to have been given Iressa/
Gefitinib
as first line treatment for stage 4 lung cancer. I had been on that almost 3 years when the cancer started to grow again.
dizzie-wh
in
The Roy Castle Lung Cancer Foundation
7 years ago
Folded nails from Gefitinib?
My Dad started
Gefitinib
on 19th Sept and has just developed the side-effect where one of his thumbnails has started to kink and fold.
My Dad started
Gefitinib
on 19th Sept and has just developed the side-effect where one of his thumbnails has started to kink and fold.
lostsheepie
in
The Roy Castle Lung Cancer Foundation
8 years ago
NSCLC, Stage 4, EGFR Mutation, Gefitinib, pain on left side of abdomen
Mum has just started her 2nd cycle (
Gefitinib
). Her alanine transaminase shot to 318. Stopped
Gefitinib
for 5 days and it dropped to 250, so it's moving in the right direction. Restarted
Gefitinib
again. She has since developed pain on the left side of her abdomen.
Mum has just started her 2nd cycle (
Gefitinib
). Her alanine transaminase shot to 318. Stopped
Gefitinib
for 5 days and it dropped to 250, so it's moving in the right direction. Restarted
Gefitinib
again. She has since developed pain on the left side of her abdomen.
Batgirlx
in
The Roy Castle Lung Cancer Foundation
8 years ago
mTOR
[T5] Phase I/II Trial of Everolimus +
gefitinib
in patients with metastatic CRPC. "The combination of
gefitinib
and everolimus did not result in significant antitumor activity.
[T5] Phase I/II Trial of Everolimus +
gefitinib
in patients with metastatic CRPC. "The combination of
gefitinib
and everolimus did not result in significant antitumor activity.
pjoshea13
in
Advanced Prostate Cancer
8 years ago
ALK mutation
Hi, I've just been told I have an ALK mutation. I'm stage 4 lung with mets to spine ,pelvis and liver. I'm waiting for a scan after three sessions of cisplatin and permetexed to see what's happening. My oncologist is looking at targeted therapies, does anyone have any success stories or have been on
Hi, I've just been told I have an ALK mutation. I'm stage 4 lung with mets to spine ,pelvis and liver. I'm waiting for a scan after three sessions of cisplatin and permetexed to see what's happening. My oncologist is looking at targeted therapies, does anyone have any success stories or have been on
Giblets9
in
The Roy Castle Lung Cancer Foundation
8 years ago
dizzie-wh
Re Iressa/
Gefitinib
. I was diagnosed as stage 4 nsclc with pleural effusion in January 2014.Tested egfr positive following a talc pleurodosis. Have been on Iressa since then with remarkable results - one scan not even being able to spot the primary!
Re Iressa/
Gefitinib
. I was diagnosed as stage 4 nsclc with pleural effusion in January 2014.Tested egfr positive following a talc pleurodosis. Have been on Iressa since then with remarkable results - one scan not even being able to spot the primary!
dizzie-wh
in
The Roy Castle Lung Cancer Foundation
9 years ago
Does anyone have any experience of ceritinib (zykadia)?
Hello all This is a new treatment for those who are ALK+. It is currently being evaluated by the Scottish Medicines Consortium. If you have any comments or experiences you would be willing to share can you let me know. Feedback from anywhere in the UK welcome, it would be used as part of the Patient
Hello all This is a new treatment for those who are ALK+. It is currently being evaluated by the Scottish Medicines Consortium. If you have any comments or experiences you would be willing to share can you let me know. Feedback from anywhere in the UK welcome, it would be used as part of the Patient
LorraineD
Roy Castle
in
The Roy Castle Lung Cancer Foundation
9 years ago
Are you EGFR+?
This is to help us make a submission to the Scottish Medicines Consortium regarding the drug
gefitinib
(Iressa). At present this drug and erlotinib (tarceva) are used to treat people with EGFR+ tumours in England and Wales. In Scotland on erlotinib is currently licensed.
This is to help us make a submission to the Scottish Medicines Consortium regarding the drug
gefitinib
(Iressa). At present this drug and erlotinib (tarceva) are used to treat people with EGFR+ tumours in England and Wales. In Scotland on erlotinib is currently licensed.
LorraineD
Roy Castle
in
The Roy Castle Lung Cancer Foundation
9 years ago
NICE decision on access to Gefitinib(Iressa) and Erlotinib (Tarceva).
We are pleased to see NICE's announcement today on second line treatment for non small cell lung cancer using
Gefitinib
(Iressa) and Erlotinib (Tarceva). Second line treatment is when someone needs further treatment after chemotherapy because their cancer has progressed.
We are pleased to see NICE's announcement today on second line treatment for non small cell lung cancer using
Gefitinib
(Iressa) and Erlotinib (Tarceva). Second line treatment is when someone needs further treatment after chemotherapy because their cancer has progressed.
LorraineD
Roy Castle
in
The Roy Castle Lung Cancer Foundation
10 years ago
Benefits of Gefitinib
We know that
Gefitinib
does not work indefinitely, but we are so grateful for the life it has given us back.
We know that
Gefitinib
does not work indefinitely, but we are so grateful for the life it has given us back.
Twiggysand
in
The Roy Castle Lung Cancer Foundation
11 years ago
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