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Experiences with
Fludarabine, cyclophosphamide and rituximab (FCR)
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unmutated
hi all is there any members who has had
fcr
who are unmutated had longer than 3 yrs remission just curious has one doctor says you can get remission up to 5 yrs plus and also which treatment would be best after
fcr
,,thank you ,,kel
hi all is there any members who has had
fcr
who are unmutated had longer than 3 yrs remission just curious has one doctor says you can get remission up to 5 yrs plus and also which treatment would be best after
fcr
,,thank you ,,kel
kel555
in
CLL Support
3 years ago
LATEST AND GREATEST LOXO-305 UPDATE
Male 71 years old, Diagnosed 2009, 6 months of
FCR
2010, 2015 Ibrutinib, 2018 Venclaxta, now LOXO-305. 11q del. C-481 mutation and I don't care to know what other blood abnormalities.
Male 71 years old, Diagnosed 2009, 6 months of
FCR
2010, 2015 Ibrutinib, 2018 Venclaxta, now LOXO-305. 11q del. C-481 mutation and I don't care to know what other blood abnormalities.
steve5441
in
CLL Support
3 years ago
covid vaccine
hi all its been a while since last post iam on my 5
fcr
this Tuesday and i can tell you this as been the hardest task i have ever done the constant worry of covid 19 as my blood counts drop after every cycle, round 3 put me in hospital with sepsis which i recovered i had a bad cough for 2 weeks before
hi all its been a while since last post iam on my 5
fcr
this Tuesday and i can tell you this as been the hardest task i have ever done the constant worry of covid 19 as my blood counts drop after every cycle, round 3 put me in hospital with sepsis which i recovered i had a bad cough for 2 weeks before
kel555
in
CLL Support
3 years ago
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Scottish Medicines Agency has decided in favour of Venetoclax plus Obintuzumab for some patients.
We have argued forcefully against the health inequalities that are becoming ever more apparent for
FCR
suitable patients but this will be a long battle we fear. Jackie
We have argued forcefully against the health inequalities that are becoming ever more apparent for
FCR
suitable patients but this will be a long battle we fear. Jackie
Jm954
Administrator
in
CLL Support
3 years ago
NHS and CLL coverage: seeking advice
My husband had
FCR
for CLL a year ago and is doing well. Grateful for your advice.
My husband had
FCR
for CLL a year ago and is doing well. Grateful for your advice.
gingerlovesal
in
CLL Support
3 years ago
Introduction
Hello, my wife was diagnosed with Stage 5 CLL in early November and commenced chemotheraphy with
FCR
on 16th November. She will be undergoing 6 cycles of chemo over 6 months. I joined this community as it seems to have excellent resources and a very supportive community.
Hello, my wife was diagnosed with Stage 5 CLL in early November and commenced chemotheraphy with
FCR
on 16th November. She will be undergoing 6 cycles of chemo over 6 months. I joined this community as it seems to have excellent resources and a very supportive community.
Tehtarek
in
CLL Support
3 years ago
Treatment of Reynauds
The only relief I had 18 months ago was when I was receiving
FCR
for my CLL and miraculously my hands were fine. Any one else have Reynauds? Any recommendations? X
The only relief I had 18 months ago was when I was receiving
FCR
for my CLL and miraculously my hands were fine. Any one else have Reynauds? Any recommendations? X
Floxxy
in
CLL Support
3 years ago
Anxiety & Dyskinesia
My wife was first diagnosed about 10 years ago and has been taking Sinemet for about 5 years which has kept her Bradykesia in check and allowed her to live a reasonably normal life. Of late though she has started to experience random short attacks of involuntary and uncontrollable movements of her body
My wife was first diagnosed about 10 years ago and has been taking Sinemet for about 5 years which has kept her Bradykesia in check and allowed her to live a reasonably normal life. Of late though she has started to experience random short attacks of involuntary and uncontrollable movements of her body
thfc1961
in
Cure Parkinson's
3 years ago
Revisiting Ibrutinib , but then no Venetoclax?
I went through
FCR
in 2014 and am now relapsing, so gearing up for the next round ...
I went through
FCR
in 2014 and am now relapsing, so gearing up for the next round ...
Me2AsWell
in
CLL Support
4 years ago
Sinemet CR at bed time
I take Sinemet int release 12.5/50 every 2 hours during the day. I have trouble waking with restless leg and anxiety about 1:00 am. Have taken 25/100 Sinemet at bedtime and make it to 3:00am. What has been the experience of taking a Sinemet CR at bedtime to extend the sleep time ? Thanks for your
I take Sinemet int release 12.5/50 every 2 hours during the day. I have trouble waking with restless leg and anxiety about 1:00 am. Have taken 25/100 Sinemet at bedtime and make it to 3:00am. What has been the experience of taking a Sinemet CR at bedtime to extend the sleep time ? Thanks for your
SGlass
in
Cure Parkinson's
3 years ago
Antibodies test CLL
I was diagnosed in 2013 and had 6 rounds of
FCR
. Would appreciate any advice please. Stay safe.
I was diagnosed in 2013 and had 6 rounds of
FCR
. Would appreciate any advice please. Stay safe.
Ellebele
in
CLL Support
4 years ago
Immediate-Release Versus Controlled-Released Carbidopa-Levodopa
The question of immediate release versus controlled-release carbidopa levodopa is a frequent topic here, so it is high time to have a post specifically addressing this issue. Chart source: https://www.ingentaconnect.com/contentone/ben/ccp/2007/00000002/00000003/art00006?crawler=true With reference
The question of immediate release versus controlled-release carbidopa levodopa is a frequent topic here, so it is high time to have a post specifically addressing this issue. Chart source: https://www.ingentaconnect.com/contentone/ben/ccp/2007/00000002/00000003/art00006?crawler=true With reference
park_bear
in
Cure Parkinson's
3 years ago
NICE approves venetoclax with obinutuzumab for patients with untreated CLL
This recommendation also gives access to CLL patients who would otherwise be suitable for the
FCR
or bendamustine and rituximab (BR). Access for this group is being funded through the Cancer Drugs Fund (CDF).
This recommendation also gives access to CLL patients who would otherwise be suitable for the
FCR
or bendamustine and rituximab (BR). Access for this group is being funded through the Cancer Drugs Fund (CDF).
HAIRBEAR_UK
Administrator
in
Leukaemia CARE
4 years ago
V+O or FCR
He can choose between
fcr
and v + o, which has only recently been approved as an initial therapy in Germany. we clearly tend towards the latter, but I would still like to ask if
fcr
should be considered?
He can choose between
fcr
and v + o, which has only recently been approved as an initial therapy in Germany. we clearly tend towards the latter, but I would still like to ask if
fcr
should be considered?
Germanguest
in
CLL Support
4 years ago
Pneumococcal vaccine
I had the pneumococcal vaccine two or three years ago, then had
FCR
chemotherapy which finished in October 2018. I’ve been invited for a second pneumococcal jab next week. My haematologist is aware. I thought I’d check to see if anyone else has done the same, and if there’s any reason I shouldn’t.
I had the pneumococcal vaccine two or three years ago, then had
FCR
chemotherapy which finished in October 2018. I’ve been invited for a second pneumococcal jab next week. My haematologist is aware. I thought I’d check to see if anyone else has done the same, and if there’s any reason I shouldn’t.
Graham2222
in
CLL Support
4 years ago
fatigue
So here I am 2yrs and 4 mths post
FCR
(6 cycles) and several months of bone marrow not producing red cells (recovered from that 8mths ago) and I'm still struggling with erratic and intermittent debilitating fatigue. I understand this affects different cancer groups.
So here I am 2yrs and 4 mths post
FCR
(6 cycles) and several months of bone marrow not producing red cells (recovered from that 8mths ago) and I'm still struggling with erratic and intermittent debilitating fatigue. I understand this affects different cancer groups.
Jotame
in
CLL Support
4 years ago
Time-to-progression after front-line FCR for CLL: a retrospective, multicohort study
It has been known for some time that
FCR
can produce very long remissions (perhaps cures) for some patients with mutated CLL.
It has been known for some time that
FCR
can produce very long remissions (perhaps cures) for some patients with mutated CLL.
Jm954
Administrator
in
CLL Support
4 years ago
Younger, Fit Patients With CLL: Goal Remains Undetectable Minimal Residual Disease and Time-Limited Therapy
Adverse events of grade 3 or higher were similar between the ibrutinib/rituximab and
FCR
arms, with more nonhematologic toxicity with ibrutinib/rituximab and more hematologic toxicity with
FCR
.
Adverse events of grade 3 or higher were similar between the ibrutinib/rituximab and
FCR
arms, with more nonhematologic toxicity with ibrutinib/rituximab and more hematologic toxicity with
FCR
.
Jm954
Administrator
in
CLL Support
4 years ago
Myelodyplastic Syndrome (MDS)
In my previous post I wrote about reaching a point 18months after completing
FCR
where my bone marrow stopped producing red cells. This got a diagnosis of MDS which was expected to be irreversible.
In my previous post I wrote about reaching a point 18months after completing
FCR
where my bone marrow stopped producing red cells. This got a diagnosis of MDS which was expected to be irreversible.
Jotame
in
CLL Support
4 years ago
Ibrutinib plus fludarabine, cyclophosphamide, and rituximab as initial treatment for younger patients with CLL
The trial was based on the premise that time-limited ibrutinib plus
FCR
would induce durable responses in younger fit patients with chronic lymphocytic leukaemia.
The trial was based on the premise that time-limited ibrutinib plus
FCR
would induce durable responses in younger fit patients with chronic lymphocytic leukaemia.
Jm954
Administrator
in
CLL Support
4 years ago
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