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Cabergoline/ Dostinex/ Casodex - Prolactin suppression to remain Hormone sensitive
Anyone taking this? Anyone know of Leslie C. Costello? Mr. Google has no newer tab than 2019 Sounds interesting but study of only one patient My memory may be challenged while on ADT as I think we may already have discussed this... ;-)) https://www.oncogen.org/full-text/the-suppression-of-prolactin-is-required-for-the-treatment-of-advanced-prostate-cancer
Anyone taking this? Anyone know of Leslie C. Costello? Mr. Google has no newer tab than 2019 Sounds interesting but study of only one patient My memory may be challenged while on ADT as I think we may already have discussed this... ;-)) https://www.oncogen.org/full-text/the-suppression-of-prolactin-is-required-for-the-treatment-of-advanced-prostate-cancer
Scout4answers
in
Advanced Prostate Cancer
1 year ago
Orgovyx-- need info/experiences
Well, my PSAs have started rising. I have one more late next week. In the past, Lupron/Casodex has successful knocked the snot out of my PSA's. Dr. Lam has suggested that I do Orgovyx next time. I have a video chat with him on the 16th. Barring a pleasant PSA surprise I will need to start it PDQ*!!
Well, my PSAs have started rising. I have one more late next week. In the past, Lupron/Casodex has successful knocked the snot out of my PSA's. Dr. Lam has suggested that I do Orgovyx next time. I have a video chat with him on the 16th. Barring a pleasant PSA surprise I will need to start it PDQ*!!
compiler
in
Advanced Prostate Cancer
1 year ago
IMRT sessions
Besides a full bladder and empty colon, what things can make radiation treatment more effective for short and long term. S.E. and outcomes?Have 4 down, 31 to go. (Had 30 days Casodex and on Lupron)
Besides a full bladder and empty colon, what things can make radiation treatment more effective for short and long term. S.E. and outcomes?Have 4 down, 31 to go. (Had 30 days Casodex and on Lupron)
runtrails
in
Advanced Prostate Cancer
1 year ago
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Prolactin-dependent malignancy- Case Report: Successful Termination of Untreatable Androgen-independent PCa with Cabergoline treatment
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6578577/ Has anyone here tried Cabergoline to suppress prolactin and slow their prostate cancer growth? The Intro, Results, Discussion and Conclusions below are short and easy to understand. For more detailed info, you can read below that or click on the
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6578577/ Has anyone here tried Cabergoline to suppress prolactin and slow their prostate cancer growth? The Intro, Results, Discussion and Conclusions below are short and easy to understand. For more detailed info, you can read below that or click on the
GeorgeGlass
in
Advanced Prostate Cancer
2 years ago
Changes
Hi everyone, my last scan showed some progression so I’m off Ibrance and
faslodex
(only got 13 months with that combo) now on Everolimus and exemestane. Anyone have any experiences to share? Hopefully good ones? Thanks Patty
Hi everyone, my last scan showed some progression so I’m off Ibrance and
faslodex
(only got 13 months with that combo) now on Everolimus and exemestane. Anyone have any experiences to share? Hopefully good ones? Thanks Patty
Gibby21
in
SHARE Metastatic Breast Cancer
2 years ago
US FDA accepts and grants priority review status to Menarini Group’s Elacestrant for patients with ER+/HER2 MBC
This is a replacement for the
Faslodex
shots. The clinical trials have shown it to be more effective and certainly less painful. The press release is below. http://www.pharmabiz.com/NewsDetails.aspx?
This is a replacement for the
Faslodex
shots. The clinical trials have shown it to be more effective and certainly less painful. The press release is below. http://www.pharmabiz.com/NewsDetails.aspx?
hopenowandtomorrow
in
SHARE Metastatic Breast Cancer
2 years ago
Should our RO's be doing HDR for Gleason 9?
My husband is 62, fit, active, but is Gleason 9 (4+5). All 12 cores were positive and he has seminal vesicle invasion and some evidence of extra capsular extension. Thankfully, Pylarify PSMA-Pet scan was clear with no lymph node or bone metastasis. So, he is cT3b N0M0. 2 urologist/surgeons thought surgery
My husband is 62, fit, active, but is Gleason 9 (4+5). All 12 cores were positive and he has seminal vesicle invasion and some evidence of extra capsular extension. Thankfully, Pylarify PSMA-Pet scan was clear with no lymph node or bone metastasis. So, he is cT3b N0M0. 2 urologist/surgeons thought surgery
Adendino
in
Advanced Prostate Cancer
2 years ago
casodex and zoladex
how long is casodex normally taken before zoladex ? The last time he was on it he took both for 16months , this time the oncologist said come in for zoladex tomorrow, I asked should he not be on casodex first he just replied yes ok come and get a prescription, I am a bit concerned he wasn’t going to
how long is casodex normally taken before zoladex ? The last time he was on it he took both for 16months , this time the oncologist said come in for zoladex tomorrow, I asked should he not be on casodex first he just replied yes ok come and get a prescription, I am a bit concerned he wasn’t going to
Merlin1960
in
Advanced Prostate Cancer
2 years ago
Follow up after MO Visit and PSMA Pet
I have taken a lot of information from this group and so very much appreciate it... Here is where my husband is at.. Saw MO and discussed the PSMA... he is castrate resistant, psa is at .20 as of Friday.. The most interesting idea she has was to try to immediately get rid of the cancer still looming
I have taken a lot of information from this group and so very much appreciate it... Here is where my husband is at.. Saw MO and discussed the PSMA... he is castrate resistant, psa is at .20 as of Friday.. The most interesting idea she has was to try to immediately get rid of the cancer still looming
Keeper70
in
Advanced Prostate Cancer
2 years ago
UPDATE AFTER IMRT
Haven't posted in a while, but here's a quick update (My Bio has the full details from diagnosis to present.). After recovering from RALP in mid February I had my PSA checked in late May. PSA was 8.11 which led to my Urology Oncologist (UO) starting me on Casodex & Eligard, and ordering a GA-68 PSMA-PET
Haven't posted in a while, but here's a quick update (My Bio has the full details from diagnosis to present.). After recovering from RALP in mid February I had my PSA checked in late May. PSA was 8.11 which led to my Urology Oncologist (UO) starting me on Casodex & Eligard, and ordering a GA-68 PSMA-PET
GMan-62
in
Advanced Prostate Cancer
2 years ago
Ibrance and faslodex
Hi. Just wondering if anyone went off these two meds because they stopped working after years and then went back on them and they worked again. I read a article from Dana Farber in Boston and it looked interesting. Thanks so much. M
Hi. Just wondering if anyone went off these two meds because they stopped working after years and then went back on them and they worked again. I read a article from Dana Farber in Boston and it looked interesting. Thanks so much. M
marianne88
in
SHARE Metastatic Breast Cancer
2 years ago
CDK12 mutation
We have had Foundation One test and Gradient Blood biopsy which both report CDK12 mutation. There is no “definitive” SOC for this rare mutation. We are in yr 5 since RP surgery, radiation, and two rounds of Lupron/Casodex. The Lupron/Casodex has stopped working. PSA went from .9 to 2.9 in 6 months
We have had Foundation One test and Gradient Blood biopsy which both report CDK12 mutation. There is no “definitive” SOC for this rare mutation. We are in yr 5 since RP surgery, radiation, and two rounds of Lupron/Casodex. The Lupron/Casodex has stopped working. PSA went from .9 to 2.9 in 6 months
JolleySprings
in
Advanced Prostate Cancer
2 years ago
Excruciating Pain!
I’ve just started Verzenio and should start
Faslodex
next Thursday. I am totally confused as whether I should be continuing on this treatment or is that my life over now? Can anyone give me any advice? Chris
I’ve just started Verzenio and should start
Faslodex
next Thursday. I am totally confused as whether I should be continuing on this treatment or is that my life over now? Can anyone give me any advice? Chris
Pachira
in
SHARE Metastatic Breast Cancer
2 years ago
First PSMA pet scan
He’s been having regular pet scans , all good, no new Mets, thank God Since PSA doubling month over month, on ADT and Casodex, time for something else? PSA still low considering. .19. seeing MO after PSMA , advise/ thoughts, TIA
He’s been having regular pet scans , all good, no new Mets, thank God Since PSA doubling month over month, on ADT and Casodex, time for something else? PSA still low considering. .19. seeing MO after PSMA , advise/ thoughts, TIA
Keeper70
in
Advanced Prostate Cancer
2 years ago
Recurrence after 2.5 year break from ADT
This is a quick note to thank all of the members here who have shared their experiences and knowledge. After a 2.5 year break from Casodex and Lupron, my husband's PSA started increasing in August 2022. It's still low but is now at 2.9. His oncologist ordered several scans including a PSMA. As results
This is a quick note to thank all of the members here who have shared their experiences and knowledge. After a 2.5 year break from Casodex and Lupron, my husband's PSA started increasing in August 2022. It's still low but is now at 2.9. His oncologist ordered several scans including a PSMA. As results
Emmett50
in
Advanced Prostate Cancer
2 years ago
Casodex bicalutamide
Any benefit taking AM or PM? Says may cause drowziness but also says may cause trouble sleeping. Starting this Wed. First Lupron Nov 1
Any benefit taking AM or PM? Says may cause drowziness but also says may cause trouble sleeping. Starting this Wed. First Lupron Nov 1
runtrails
in
Advanced Prostate Cancer
2 years ago
Opinion?
Newly diagnosed, Gleason 9, PSA about 40 at biopsy, aggressive, PET shows low burden, two bone mets. At my age 82, although health "very good", Onc wants to avoid chemo. Just started on Casodex and will add Lupron, until PSA under control then add (switch to?) Zytiga and radiation to clean up prostate
Newly diagnosed, Gleason 9, PSA about 40 at biopsy, aggressive, PET shows low burden, two bone mets. At my age 82, although health "very good", Onc wants to avoid chemo. Just started on Casodex and will add Lupron, until PSA under control then add (switch to?) Zytiga and radiation to clean up prostate
Wgly
in
Advanced Prostate Cancer
2 years ago
Switching from Faslodex to Xeloda
At my appointment this morning, the oncologist reported that he is switching me off the hormonal (
Faslodex
) and putting me on chemo (Xeloda). I know many of you have taken this path. If you have any suggestions, please share.
At my appointment this morning, the oncologist reported that he is switching me off the hormonal (
Faslodex
) and putting me on chemo (Xeloda). I know many of you have taken this path. If you have any suggestions, please share.
CincinnatiExperience
in
SHARE Metastatic Breast Cancer
2 years ago
Night Sweats from Faslodex
Hi everyone, I have been experiencing night sweats and the occasional hot flash presumably a side effect of
Faslodex
. I have been getting it since September, but this has not been an issue until recently.
Hi everyone, I have been experiencing night sweats and the occasional hot flash presumably a side effect of
Faslodex
. I have been getting it since September, but this has not been an issue until recently.
Maddyandherkittens
in
SHARE Metastatic Breast Cancer
2 years ago
first PSMA
What was your timeline? I know my RO said in our last meeting, assuming PSMA is node neg and distant met neg), that I would start Casodex (I already have the pills) day after the scan, a couple weeks later, Lupron, and the a couple weeks later the first full pelvic radiation (35 at 70 grey) Is that
What was your timeline? I know my RO said in our last meeting, assuming PSMA is node neg and distant met neg), that I would start Casodex (I already have the pills) day after the scan, a couple weeks later, Lupron, and the a couple weeks later the first full pelvic radiation (35 at 70 grey) Is that
runtrails
in
Advanced Prostate Cancer
2 years ago
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