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Abiraterone Failure
I began Abiraterone on Jan 11,2020...my last three PSA readings are .76 12/11/20), 2.1 (2/25/20), 3.9 (3/27/20)...so I have failed abiraterone...(have ruled out BRCA2+ mutation...also I believe we have ruled out AR-V7 expression)..my alkaline phosphate remains good at 45...next choice seems to be enzalutamide
I began Abiraterone on Jan 11,2020...my last three PSA readings are .76 12/11/20), 2.1 (2/25/20), 3.9 (3/27/20)...so I have failed abiraterone...(have ruled out BRCA2+ mutation...also I believe we have ruled out AR-V7 expression)..my alkaline phosphate remains good at 45...next choice seems to be enzalutamide
Chivato646
in
Advanced Prostate Cancer
5 years ago
Lupron Altarnatives
Can anyone recommend a urologist in eastern US who is currently using Vantas implants with Casodex as an alternative to Lupron? I have been unable to find one anywhere near my location. From other posts, it appears that some community members are using this combo with success. Any advice will be much
Can anyone recommend a urologist in eastern US who is currently using Vantas implants with Casodex as an alternative to Lupron? I have been unable to find one anywhere near my location. From other posts, it appears that some community members are using this combo with success. Any advice will be much
mangeycritter
in
Advanced Prostate Cancer
5 years ago
Afinitor or clinical trial
The ibrance or possibly the
faslodex
is no longer working for me or my cancer is progressing now on that. I am advised that I have a mutation that would indicate afinitor is the best med. Or another option would be to go on a clinical trial.
The ibrance or possibly the
faslodex
is no longer working for me or my cancer is progressing now on that. I am advised that I have a mutation that would indicate afinitor is the best med. Or another option would be to go on a clinical trial.
Wolverine19
in
SHARE Metastatic Breast Cancer
5 years ago
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Borders and Chemotherapy
I'm up against a unique problem and do not know where to go to get an answer. A quick update on me. 65, initial psa 55, Gleason 9 in 16. No mets visible. Radiation summer of 16. Been on Erleada, Zolodex, Xtandi, Casodex, and Zytiga recently. All failed eventually. Doctor said Docetaxal is all that
I'm up against a unique problem and do not know where to go to get an answer. A quick update on me. 65, initial psa 55, Gleason 9 in 16. No mets visible. Radiation summer of 16. Been on Erleada, Zolodex, Xtandi, Casodex, and Zytiga recently. All failed eventually. Doctor said Docetaxal is all that
dpowellnt
in
Advanced Prostate Cancer
5 years ago
Fluctuations psa
hello, what do you think? my father 69 years old Radical prostatectomy 2016 pt 3b gleason 8 psa post op 0.24 3 months later 0.56 Radiotherapy 2017 that failed psa a year later about 2 Tepscan ok in September 2018: lupron, casodex December 2018 psa 0.08 April 2019 0.11 Octobre 2019 0,10 April 2020 0,13
hello, what do you think? my father 69 years old Radical prostatectomy 2016 pt 3b gleason 8 psa post op 0.24 3 months later 0.56 Radiotherapy 2017 that failed psa a year later about 2 Tepscan ok in September 2018: lupron, casodex December 2018 psa 0.08 April 2019 0.11 Octobre 2019 0,10 April 2020 0,13
Katiafrench
in
Advanced Prostate Cancer
5 years ago
experience w/neutropenia?!
hey all- my husband is dealing w/neutropenia. he takes casodex & tamoxifen daily. have any of you experienced this before? hematologist thinks it may be related to the tamoxifen, but isn't sure. worried about him being even more immunocompromised right now.
hey all- my husband is dealing w/neutropenia. he takes casodex & tamoxifen daily. have any of you experienced this before? hematologist thinks it may be related to the tamoxifen, but isn't sure. worried about him being even more immunocompromised right now.
pwallace
in
Advanced Prostate Cancer
5 years ago
Salvage Radiation Delay due to COVID 19
RO Mychalczak at Memorial Sloan Kettering Westchester (just outside Manhattan) wants to delay my 8 weeks of salvage radiation to Pelvic Lymph Nodes Prostate Bed due to Pandemic. Suggesting a 3 month shot of Lupron to keep PSA down in the interim My concern is that the Lupron may be keeping the PSA
RO Mychalczak at Memorial Sloan Kettering Westchester (just outside Manhattan) wants to delay my 8 weeks of salvage radiation to Pelvic Lymph Nodes Prostate Bed due to Pandemic. Suggesting a 3 month shot of Lupron to keep PSA down in the interim My concern is that the Lupron may be keeping the PSA
sharpcut
in
Advanced Prostate Cancer
5 years ago
Stats... devils (or angels) in the details?
I came across an interesting example of why it can be worthwhile to dig into the details that underlie statistic-based conclusions. (And I wasn't really digging that hard, this one fell into my lap.) In considering anti-androgen monotherapy as an initial systemic treatment for my metastatic 3+4=7 PC,
I came across an interesting example of why it can be worthwhile to dig into the details that underlie statistic-based conclusions. (And I wasn't really digging that hard, this one fell into my lap.) In considering anti-androgen monotherapy as an initial systemic treatment for my metastatic 3+4=7 PC,
noahware
in
Advanced Prostate Cancer
5 years ago
Update - Post CT scan results
Hi everyone, I'm 58 and diagnosed in Dec 2019 with Stage IV, GS 9, PSA 50. It spread into my Bladder, blocked my left Ureter and formed 3 Mets on my Pelvis. I am on daily Casodex, 3 monthly Eligard, completed 3 Docetaxel IVs and had a Ureter stent inserted. I have just received the Pathology results
Hi everyone, I'm 58 and diagnosed in Dec 2019 with Stage IV, GS 9, PSA 50. It spread into my Bladder, blocked my left Ureter and formed 3 Mets on my Pelvis. I am on daily Casodex, 3 monthly Eligard, completed 3 Docetaxel IVs and had a Ureter stent inserted. I have just received the Pathology results
Doseydoe
in
Advanced Prostate Cancer
5 years ago
Visiting the hospital amidst COVID 19 scare ?
My dad is due for his 3-monthly Lupron shot on April 3rd. He is currently on Casodex + Lupron. He completed his chemo this January. As if dealing with the idea of advanced Pca wasn’t enough, the COVID-19 is a reminder of the fragility of our lives once again. How is everyone managing visiting the hospital
My dad is due for his 3-monthly Lupron shot on April 3rd. He is currently on Casodex + Lupron. He completed his chemo this January. As if dealing with the idea of advanced Pca wasn’t enough, the COVID-19 is a reminder of the fragility of our lives once again. How is everyone managing visiting the hospital
Cheerr
in
Advanced Prostate Cancer
5 years ago
Go to MO or not?
Been on Lupron, Casodex, Avodart forever. MO Appt tomorrow here in NJ. No discernible Covid 19 symptoms; T=97.5-98.5F! Do I go or postpone? (84, GS6, T2B in 1997, Pd+XBRT,recurred in 2001. Current psa on hormones: 0.4!; hi bp, triple bypass in '17). They say they will "screen", whatever that means
Been on Lupron, Casodex, Avodart forever. MO Appt tomorrow here in NJ. No discernible Covid 19 symptoms; T=97.5-98.5F! Do I go or postpone? (84, GS6, T2B in 1997, Pd+XBRT,recurred in 2001. Current psa on hormones: 0.4!; hi bp, triple bypass in '17). They say they will "screen", whatever that means
herb1
in
Advanced Prostate Cancer
5 years ago
Basic Question About Casodex
Is Casodex used primarily to avoid PSA flare when starting Lupron? If so how long does it need to be taken? If so would starting ADT with a degaralix injection instead and then transitioning to lupron after a month be equally or more effective?
Is Casodex used primarily to avoid PSA flare when starting Lupron? If so how long does it need to be taken? If so would starting ADT with a degaralix injection instead and then transitioning to lupron after a month be equally or more effective?
6357axbz
in
Advanced Prostate Cancer
5 years ago
Imaging at Low PSA
I was on Lupron + Casodex for a year for lymph node metastasis. In November 2019, I started ADT vacation. My last Lupron shot was in September, 2019. In February 2020, my PSA was 0.07 (slightly up from 0.06 in November 2019) and T <20. Today, I learned that my MO wants me to have chest X ray, Abdomen
I was on Lupron + Casodex for a year for lymph node metastasis. In November 2019, I started ADT vacation. My last Lupron shot was in September, 2019. In February 2020, my PSA was 0.07 (slightly up from 0.06 in November 2019) and T <20. Today, I learned that my MO wants me to have chest X ray, Abdomen
dac500
in
Advanced Prostate Cancer
5 years ago
Fatigue, Pain & Other Fun Stuff
Good Morning Everyone.... I have a couple of questions and I know you can help me out. Hubby’s PC recurred at the end of 2016. Since then he’s had casodex, lupron, 6 of taxotere, Zytiga, 9 of cabazitazel + carboplatin, Xtandi, Keytruda, 6 more of cabazitazel + carboplatin, 5 days of radiation for pain
Good Morning Everyone.... I have a couple of questions and I know you can help me out. Hubby’s PC recurred at the end of 2016. Since then he’s had casodex, lupron, 6 of taxotere, Zytiga, 9 of cabazitazel + carboplatin, Xtandi, Keytruda, 6 more of cabazitazel + carboplatin, 5 days of radiation for pain
Luv2fish
in
Advanced Prostate Cancer
5 years ago
Rash/ Verzinio,Faslodex,xgeva
Hi all hope everyone is doing well. Has anyone had problems with a rash on any of these treatments. Mine started on my chest went to dermatologist gave me an ointment to put on and it did nothing. It’s now also on arms legs and stomach. It’s mostly a flat rash with few raised itchy and burning feeling
Hi all hope everyone is doing well. Has anyone had problems with a rash on any of these treatments. Mine started on my chest went to dermatologist gave me an ointment to put on and it did nothing. It’s now also on arms legs and stomach. It’s mostly a flat rash with few raised itchy and burning feeling
Barb5
in
SHARE Metastatic Breast Cancer
5 years ago
Last visit with MO???
My 67 y/o husband was diagnosed in October 2017 with Gleason 9 and PSA was 41 at start of ADT of Casodex and Lupron in March 2018. He had 39 sessions of EBRT; some to nearby lymph nodes and balance to prostate. His last 4 PSA: 6/19 at .02, 8/19 at .02, 11/19 at <.01 and 2/20 at <.01. His last Lupron
My 67 y/o husband was diagnosed in October 2017 with Gleason 9 and PSA was 41 at start of ADT of Casodex and Lupron in March 2018. He had 39 sessions of EBRT; some to nearby lymph nodes and balance to prostate. His last 4 PSA: 6/19 at .02, 8/19 at .02, 11/19 at <.01 and 2/20 at <.01. His last Lupron
Emmett50
in
Advanced Prostate Cancer
5 years ago
Abiraterone Withdrawal Syndrome - anyone experience it?
A friend of mine stopped Zytiga and his PSA went [i]down[/i]. I'm familiar with bicalutamide withdrawal syndrome: PSA increases after a while taking Casodex but goes down when Casodex is stopped. This is caused by the Androgen Receptor using bicalutamide to become activated, and is well known. I've even
A friend of mine stopped Zytiga and his PSA went [i]down[/i]. I'm familiar with bicalutamide withdrawal syndrome: PSA increases after a while taking Casodex but goes down when Casodex is stopped. This is caused by the Androgen Receptor using bicalutamide to become activated, and is well known. I've even
Tall_Allen
in
Advanced Prostate Cancer
5 years ago
First PSA Three Months After Starting ADT Vacation
Lupron + Casodex treatment for my lymph node metastases (multiple pelvic and abdomen nodes) was started in November 2018 with a PSA of 4.48. By November, 2019 the PSA dropped to 0.06, when on doctor's advice I started a vacation from ADT. Three months later my PSA is 0.07. My last 3-month Lupron was
Lupron + Casodex treatment for my lymph node metastases (multiple pelvic and abdomen nodes) was started in November 2018 with a PSA of 4.48. By November, 2019 the PSA dropped to 0.06, when on doctor's advice I started a vacation from ADT. Three months later my PSA is 0.07. My last 3-month Lupron was
dac500
in
Advanced Prostate Cancer
5 years ago
PSA Higher 30 days into Abiraterone
my PSA has jumped from .761 on December 11th to 2.09 as of February 25th...I stopped my 50 mg Casodex and began 1,000 mg Abiraterone on January 25th...have an MO appointment tomorrow...all other blood work is outstanding (Alk Phos 47, C-reactive protein <1, kidneys & liver handling the Abiraterone /
my PSA has jumped from .761 on December 11th to 2.09 as of February 25th...I stopped my 50 mg Casodex and began 1,000 mg Abiraterone on January 25th...have an MO appointment tomorrow...all other blood work is outstanding (Alk Phos 47, C-reactive protein <1, kidneys & liver handling the Abiraterone /
Chivato646
in
Advanced Prostate Cancer
5 years ago
Rise in ALP level, PSA continues to fall, what can it mean?
My dad's ALP went down to 81 last month after 6 cycles of chemo. He then moved on to Lupron + Casodex. After 1 month, its now risen from 81 to 121. He also has little pain on and off in his back and thighs from 4 days. He has stopped taking his painkiller since a month and doesn't need them yet.
My dad's ALP went down to 81 last month after 6 cycles of chemo. He then moved on to Lupron + Casodex. After 1 month, its now risen from 81 to 121. He also has little pain on and off in his back and thighs from 4 days. He has stopped taking his painkiller since a month and doesn't need them yet.
Cheerr
in
Advanced Prostate Cancer
5 years ago
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