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Docetaxel
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Advance prostate cancer.
I am now starting on hormone therapy and chemotherapy with
Docetaxel
for 6 cycles. Does anybody have any idea of what I'm in for?
I am now starting on hormone therapy and chemotherapy with
Docetaxel
for 6 cycles. Does anybody have any idea of what I'm in for?
DavidT-55
in
Advanced Prostate Cancer
8 years ago
Given another 18 months of life if continue treatment. Starting cabazitaxel this week. Side effects?
He reluctantly decided on Jevtana and external beam radiation even though he had a difficult time with
docetaxel
. Anyone have more side effects with cabazitaxel than with
docetaxel
? We are not that thrilled with Jevtana as his PSA only climbed and bone mets got worse while on
docetaxel
.
He reluctantly decided on Jevtana and external beam radiation even though he had a difficult time with
docetaxel
. Anyone have more side effects with cabazitaxel than with
docetaxel
? We are not that thrilled with Jevtana as his PSA only climbed and bone mets got worse while on
docetaxel
.
Cancersucks
in
Advanced Prostate Cancer
8 years ago
Docetaxel and Nintedanib
I am just about to start on
Docetaxel
and Nintedanib and have been told that this will give me weeks or months more life. I understand that the side effects are quite severe and wondered if anyone else has been on these drugs and could tell me their experience. Thanks, Lorna
I am just about to start on
Docetaxel
and Nintedanib and have been told that this will give me weeks or months more life. I understand that the side effects are quite severe and wondered if anyone else has been on these drugs and could tell me their experience. Thanks, Lorna
tilstongal
in
The Roy Castle Lung Cancer Foundation
8 years ago
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Docetaxel, Total Number of Cycles & Overall Survival
"The Mainsail trial was a multinational randomized phase 3 study of 1059 patients with mCRPC receiving
docetaxel
, prednisone, and lenalidomide (DPL) or
docetaxel
, prednisone, and a placebo (DP). Study patients were treated until progressive disease or unacceptable adverse effects occurred.
"The Mainsail trial was a multinational randomized phase 3 study of 1059 patients with mCRPC receiving
docetaxel
, prednisone, and lenalidomide (DPL) or
docetaxel
, prednisone, and a placebo (DP). Study patients were treated until progressive disease or unacceptable adverse effects occurred.
pjoshea13
in
Advanced Prostate Cancer
8 years ago
Foods/Supplements-Vitamins: BioPerine / CYP3A4
"The synergistic administration of piperine and
docetaxel
significantly improved the anti-tumor efficacy of
docetaxel
in a xenograft model of human CRPC."
"The synergistic administration of piperine and
docetaxel
significantly improved the anti-tumor efficacy of
docetaxel
in a xenograft model of human CRPC."
pjoshea13
in
Advanced Prostate Cancer
8 years ago
History of my journey
Zoladex for five and a half years, TRAPEZE trial -
docetaxel
and zoladronic acid. Abiraterone (had to come off for toxicity reasons), Enzalutamide and now cabazitaxel.
Zoladex for five and a half years, TRAPEZE trial -
docetaxel
and zoladronic acid. Abiraterone (had to come off for toxicity reasons), Enzalutamide and now cabazitaxel.
HughVG
in
Fight Prostate Cancer
8 years ago
Foods/Supplements-Vitamins: Parthenolide - Feverfew
Parthenolide also augmented the in vivo efficacy of
docetaxel
and restored sensitivity to anti-androgen therapy." [7c] (2009 - U.S.)
Parthenolide also augmented the in vivo efficacy of
docetaxel
and restored sensitivity to anti-androgen therapy." [7c] (2009 - U.S.)
pjoshea13
in
Advanced Prostate Cancer
8 years ago
Trial at the Christie
Hi, Since my last post about Immunotherapy a lot has happened, I was initially going to start on
Docetaxel
/Nintedanib tomorrow as the trial at the Christie was full. Then i had a call from them to say there was a place for me after all and i start the screening process on Thursday.
Hi, Since my last post about Immunotherapy a lot has happened, I was initially going to start on
Docetaxel
/Nintedanib tomorrow as the trial at the Christie was full. Then i had a call from them to say there was a place for me after all and i start the screening process on Thursday.
caitesnan59
in
The Roy Castle Lung Cancer Foundation
8 years ago
Non-PCa Prescription Drugs: Nitroglycerin
The effects and mechanisms of nitroglycerin on the enhancement of chemosensitivity to
docetaxel
and carboplatin regimen (DCb) in patients with lung adenocarcinoma have not been reported."
The effects and mechanisms of nitroglycerin on the enhancement of chemosensitivity to
docetaxel
and carboplatin regimen (DCb) in patients with lung adenocarcinoma have not been reported."
pjoshea13
in
Advanced Prostate Cancer
8 years ago
Foods/Supplements-Vitamins: Lycopene - Tomatoes
Not clear what these two
Docetaxel
trials hope to achieve. [4a] "
Docetaxel
Plus Lycopene in Castration Resistant, Chemotherapy-Naïve Prostate Cancer Patients" Lyc-O-Mato Recruiting.
Not clear what these two
Docetaxel
trials hope to achieve. [4a] "
Docetaxel
Plus Lycopene in Castration Resistant, Chemotherapy-Naïve Prostate Cancer Patients" Lyc-O-Mato Recruiting.
pjoshea13
in
Advanced Prostate Cancer
8 years ago
Next steps?
I know my Seattle doc is participating in a trial using
docetaxel
, Carboplatin and sirolimus. The doctor ar Duke mentioned trying oxaliplatin with Gezmar.
I know my Seattle doc is participating in a trial using
docetaxel
, Carboplatin and sirolimus. The doctor ar Duke mentioned trying oxaliplatin with Gezmar.
Gecrellin
in
Advanced Prostate Cancer
8 years ago
Here we go again
the spelling) which he sailed through no side effects, had follow up scans where it showed it had shrunk a bit, so friday we went to the oncologist and were told it had grown although they couldnt guarantee that it was cancer and not a chest infection, so Tuesday he starts Chemo again this time on
Docetaxel
the spelling) which he sailed through no side effects, had follow up scans where it showed it had shrunk a bit, so friday we went to the oncologist and were told it had grown although they couldnt guarantee that it was cancer and not a chest infection, so Tuesday he starts Chemo again this time on
Docetaxel
frankiedarv
in
The Roy Castle Lung Cancer Foundation
8 years ago
Immunotherapy
I was offered
Docetaxel
/ nintednib but asked if i could have either imunotherapy or some other targeted therapy instead. I was sent to the Christie in the hope of joining a trial but was told on arrival that the trial was full.
I was offered
Docetaxel
/ nintednib but asked if i could have either imunotherapy or some other targeted therapy instead. I was sent to the Christie in the hope of joining a trial but was told on arrival that the trial was full.
caitesnan59
in
The Roy Castle Lung Cancer Foundation
8 years ago
Foods/Supplements-Vitamins: Arginine - Nitric Oxide
"Conclusions: ADI-PEG 20 demonstrated reasonable toxicity in combination with
docetaxel
. Promising clinical activity was noted, and expansion cohorts are now accruing for ... castrate-resistant prostate cancer ... at a recommended phase II dose of 36 mg/m2." ...
"Conclusions: ADI-PEG 20 demonstrated reasonable toxicity in combination with
docetaxel
. Promising clinical activity was noted, and expansion cohorts are now accruing for ... castrate-resistant prostate cancer ... at a recommended phase II dose of 36 mg/m2." ...
pjoshea13
in
Advanced Prostate Cancer
8 years ago
Neutrophil to Lymphocyte Ratio, Xtandi, & Outcome in CRPC
"We included consecutive metastatic CRPC patients treated with enzalutamide after
docetaxel
" "Data collected on 193 patients from 9 centers were evaluated." "The median baseline NLR was 3.2."
"We included consecutive metastatic CRPC patients treated with enzalutamide after
docetaxel
" "Data collected on 193 patients from 9 centers were evaluated." "The median baseline NLR was 3.2."
pjoshea13
in
Advanced Prostate Cancer
8 years ago
Knee pain after BC treatment
I had BCS surgery followed by a sandwich therapy of 4 cycles of chemotherapy FEC, radiation and 4 cycles of
docetaxel
. My BC is stage 2A, Pt2n0m0, ER/PR positive and Her2 neu negative by FISH test. My treatment completed on February 2016 and currently I am on hormone therapy taking tamoxifen daily.
I had BCS surgery followed by a sandwich therapy of 4 cycles of chemotherapy FEC, radiation and 4 cycles of
docetaxel
. My BC is stage 2A, Pt2n0m0, ER/PR positive and Her2 neu negative by FISH test. My treatment completed on February 2016 and currently I am on hormone therapy taking tamoxifen daily.
Delhiresident
in
Breast Cancer India
8 years ago
Nintedanib and Docetaxel
Consequently the decision is we will try Nintedanib and
Docetaxel
together. I know this is a fairly new combination drug and would like to know from anyone who has been on it recently. A few seem to have had it a while ago whilst it was presumably a trial drug combination.
Consequently the decision is we will try Nintedanib and
Docetaxel
together. I know this is a fairly new combination drug and would like to know from anyone who has been on it recently. A few seem to have had it a while ago whilst it was presumably a trial drug combination.
JeanneLe
in
The Roy Castle Lung Cancer Foundation
8 years ago
Foods/Supplements-Vitamins: Arachidonic acid [AA]
STAMPEDE--an international, open-label, randomised controlled trial--uses a novel multiarm, multistage design to assess whether the early additional use of one or two drugs (
docetaxel
, zoledronic acid, celecoxib, zoledronic acid and
docetaxel
, or zoledronic acid and celecoxib) improves survival in men
STAMPEDE--an international, open-label, randomised controlled trial--uses a novel multiarm, multistage design to assess whether the early additional use of one or two drugs (
docetaxel
, zoledronic acid, celecoxib, zoledronic acid and
docetaxel
, or zoledronic acid and celecoxib) improves survival in men
pjoshea13
in
Advanced Prostate Cancer
8 years ago
Foods/Supplements-Vitamins: Curcumin
"...
docetaxel
/prednisone in standard conditions for 6 cycles in combination with per os curcumin, 6,000 mg/day (day -4 to day +2 of
docetaxel
)." "Twenty-six patients received the scheduled treatment, 2 progressed and 2 died before the end of treatment.
"...
docetaxel
/prednisone in standard conditions for 6 cycles in combination with per os curcumin, 6,000 mg/day (day -4 to day +2 of
docetaxel
)." "Twenty-six patients received the scheduled treatment, 2 progressed and 2 died before the end of treatment.
pjoshea13
in
Advanced Prostate Cancer
8 years ago
My path to Precision Medicine
I got tired of standard of care (diagnosed 3/14, surgery 4/14 (gleason 9, 85% of prostate with tumor, seminal vesicle invasion - just a mess), pelvic bone mets found 6/14 (6 week post-op PSA of 3.76...crazy), started eligard and 6 rounds of
docetaxel
7/14 thinking I was still hormone sensitive, bone
I got tired of standard of care (diagnosed 3/14, surgery 4/14 (gleason 9, 85% of prostate with tumor, seminal vesicle invasion - just a mess), pelvic bone mets found 6/14 (6 week post-op PSA of 3.76...crazy), started eligard and 6 rounds of
docetaxel
7/14 thinking I was still hormone sensitive, bone
Bryce
in
Fight Prostate Cancer
8 years ago
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