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Docetaxel failure
Here we are again Xytiga , Xtandi And now
Docetaxel
have failed .. my dad only got through 5 of 6 rounds before his psa started going up. He’s at a 10 now and waiting for a new round of scans and next course of treatment . I’m trying to reassure him there is more treatment available to him.
Here we are again Xytiga , Xtandi And now
Docetaxel
have failed .. my dad only got through 5 of 6 rounds before his psa started going up. He’s at a 10 now and waiting for a new round of scans and next course of treatment . I’m trying to reassure him there is more treatment available to him.
Stumpgirl
in
Advanced Prostate Cancer
2 years ago
What does recent biopsy mean positive for NKX3.1?
Any suggestions for future tests & treatments/trials (currently infusions of
Docetaxel
+ Carboplantin every 3 weeks for possibly 3-6 more infusions)?
Any suggestions for future tests & treatments/trials (currently infusions of
Docetaxel
+ Carboplantin every 3 weeks for possibly 3-6 more infusions)?
julyturqsee
in
Advanced Prostate Cancer
2 years ago
When Docetaxel Isn't Working
After 4
Docetaxel
infusions out of 9 planned & bone & pelvic scans, the cancer is spreading on the spine (new & enlarged metastases) & pelvis. PSA remains low (less than 4). Side effects of the
Docetaxel
has impacted quality of life (extreme fatigue, listlessness, depression).
After 4
Docetaxel
infusions out of 9 planned & bone & pelvic scans, the cancer is spreading on the spine (new & enlarged metastases) & pelvis. PSA remains low (less than 4). Side effects of the
Docetaxel
has impacted quality of life (extreme fatigue, listlessness, depression).
julyturqsee
in
Advanced Prostate Cancer
2 years ago
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Psa
He has been on Zytiga, Lynparza, Keytruda,
Docetaxel
and now Jentava. He had his last round of
Docetaxel
around Oct. 25th . His psa at that point was 70 . He had his first round of Jentava three weeks ago just had a psa check today it’s now 83.4.
He has been on Zytiga, Lynparza, Keytruda,
Docetaxel
and now Jentava. He had his last round of
Docetaxel
around Oct. 25th . His psa at that point was 70 . He had his first round of Jentava three weeks ago just had a psa check today it’s now 83.4.
Fight11
in
Advanced Prostate Cancer
2 years ago
Digging into STAMPEDE data fir SBRT
There is a strong benefit to radiation, as shown on the last line of the table, when patients were treated with
docetaxel
.
There is a strong benefit to radiation, as shown on the last line of the table, when patients were treated with
docetaxel
.
Javelin18
in
Advanced Prostate Cancer
2 years ago
PSA Increasing on Lu177 + Enzalutamide.
*Previous Treatment* : Abiretrone, 9
Docetaxel
, 9 Cabazitaxel....
*Previous Treatment* : Abiretrone, 9
Docetaxel
, 9 Cabazitaxel....
pka21
in
Advanced Prostate Cancer
2 years ago
And on it goes…Car T trial in process at Dana Farber. Anyone else doing Car T? Advice, comments welcome
Quick update: brother DX 2018, G9 with Mets, Lupron,
Docetaxel
, Provenge, Zytiga,Xtandi, ARV 110 trial, Keytruda (msh2 +6, HTB). Keytruda lasted eight months with no side effects. Bone scan in November stable with ALP at 109. PSA rose to 45 and lymph nodes were all growing.
Quick update: brother DX 2018, G9 with Mets, Lupron,
Docetaxel
, Provenge, Zytiga,Xtandi, ARV 110 trial, Keytruda (msh2 +6, HTB). Keytruda lasted eight months with no side effects. Bone scan in November stable with ALP at 109. PSA rose to 45 and lymph nodes were all growing.
Faith1111
in
Advanced Prostate Cancer
2 years ago
Chemo (Docetaxel) not working 76 YO
He started
docetaxel
on October 2021, His PSA was ~ 20 in October 2021, now today’s (3-Dec-2021) PSA test shows it is 98. This is after 4 infusions. Does this mean
Docetaxel
is ineffective? Or do we have to give it more time before we see good results? Please help. Thanks.
He started
docetaxel
on October 2021, His PSA was ~ 20 in October 2021, now today’s (3-Dec-2021) PSA test shows it is 98. This is after 4 infusions. Does this mean
Docetaxel
is ineffective? Or do we have to give it more time before we see good results? Please help. Thanks.
Vishwa1890
in
Advanced Prostate Cancer
2 years ago
Docetaxel - Number of sessions in SOC
Docetaxel
- Why the difference in SOC between UK and Canada? Apparently the SOC in UK is 10 sessions. It's 6 sessions in Canada (and US, I think). Anyone know why the difference and any trials that show which is most beneficial? Thanks.
Docetaxel
- Why the difference in SOC between UK and Canada? Apparently the SOC in UK is 10 sessions. It's 6 sessions in Canada (and US, I think). Anyone know why the difference and any trials that show which is most beneficial? Thanks.
davebliz
in
Advanced Prostate Cancer
2 years ago
Chemo
Docetaxel
is not working. Going to ask for Jenteva not sure the spelling. That is fourth failed treatment. Zytiga, Lynparza, Keytruda now
Docetaxel
. So petrified this is the beginning of the end. Could really use some words of encouragement. Something has to work!!!!! 😭
Docetaxel
is not working. Going to ask for Jenteva not sure the spelling. That is fourth failed treatment. Zytiga, Lynparza, Keytruda now
Docetaxel
. So petrified this is the beginning of the end. Could really use some words of encouragement. Something has to work!!!!! 😭
Fight11
in
Advanced Prostate Cancer
2 years ago
Chemo: need suggestions
Hello everyone My father has taken 2 rounds of
docetaxel
chemo.He feels very fatigued and his hb level is 8.0 while RBC is 2.82. Chemo has already been delayed by about a month. However my father still feels very weak and is not ready to do another round of chemo.
Hello everyone My father has taken 2 rounds of
docetaxel
chemo.He feels very fatigued and his hb level is 8.0 while RBC is 2.82. Chemo has already been delayed by about a month. However my father still feels very weak and is not ready to do another round of chemo.
Vsahay
in
Advanced Prostate Cancer
2 years ago
Chemo with docetaxel?
One specialist has proposed starting chemo with
docetaxel
. My PSA recently rose to 38 from 27 and the stereotactic radiation I had in Cyprus last May (2021) for left and right side abdominal lymph nodes appears not to have worked. I will be 78 at my next birthday, 15 July 2022.
One specialist has proposed starting chemo with
docetaxel
. My PSA recently rose to 38 from 27 and the stereotactic radiation I had in Cyprus last May (2021) for left and right side abdominal lymph nodes appears not to have worked. I will be 78 at my next birthday, 15 July 2022.
Arcticfox44
in
Advanced Prostate Cancer
2 years ago
Fathers update:
Psa down to 16 before
docetaxel
Monthly hormone injections now replaced by quarterly injections Before 5th dose of chemo Psa down to 0.3 One more dose of chemo to go and then we will have to see what the new year brings.
Psa down to 16 before
docetaxel
Monthly hormone injections now replaced by quarterly injections Before 5th dose of chemo Psa down to 0.3 One more dose of chemo to go and then we will have to see what the new year brings.
Jordanh97
in
Advanced Prostate Cancer
2 years ago
Docetaxel
He is now on
Docetaxel
he had his fourth round today. Psa does not seem to be responding. He will have bone scans and ct scan.Is there something he can take in conjunction with the chemo? If this treatment fails I don’t know where to go from here.
He is now on
Docetaxel
he had his fourth round today. Psa does not seem to be responding. He will have bone scans and ct scan.Is there something he can take in conjunction with the chemo? If this treatment fails I don’t know where to go from here.
Fight11
in
Advanced Prostate Cancer
3 years ago
Not responding
With the
Docetaxel
his psa just keeps going up. He just had his fourth round. Spoke with his local oncologist yesterday. He said if someone doesn’t respond to
Docetaxel
it ususally is a poor prognosis. I have not yet heard from Dana Farber Dr Beltran. I want to see if she feels the same.
With the
Docetaxel
his psa just keeps going up. He just had his fourth round. Spoke with his local oncologist yesterday. He said if someone doesn’t respond to
Docetaxel
it ususally is a poor prognosis. I have not yet heard from Dana Farber Dr Beltran. I want to see if she feels the same.
Fight11
in
Advanced Prostate Cancer
2 years ago
Experiencing Leg muscle weakness post chemo, not able to walk more than 2-3 mins, any advice?
Completed 10
docetaxel
session on 19th October. After 9th chemo I experienced left leg muscle getting tired only after 2-3 mins of walk and I needed to sit. On doctor's advice started pregabalin 75 twice daily from 12th October. Got back to normalcy after 2 days. Stopped med on 15th November.
Completed 10
docetaxel
session on 19th October. After 9th chemo I experienced left leg muscle getting tired only after 2-3 mins of walk and I needed to sit. On doctor's advice started pregabalin 75 twice daily from 12th October. Got back to normalcy after 2 days. Stopped med on 15th November.
Soumen79
in
Advanced Prostate Cancer
2 years ago
Chemo induced anemia
My father has had 2 cycles of
docetaxel
chemo and his Hb is 8.2 g/dl while RBC is 2.96 mcL. Due to this, the next chemo has been postponed by a week The MO says the only way anemia can be dealt is blood transfusion if Hb goes below 8 g/dl.
My father has had 2 cycles of
docetaxel
chemo and his Hb is 8.2 g/dl while RBC is 2.96 mcL. Due to this, the next chemo has been postponed by a week The MO says the only way anemia can be dealt is blood transfusion if Hb goes below 8 g/dl.
Vsahay
in
Advanced Prostate Cancer
2 years ago
Genetic Pathology Report is in, now what?
Before we discuss with MO (who replies the findings indicate continuation of SOC (
Docetaxel
+ Carboplatin), the key oncogenic markers are: ERBB3 (2.3%), MYC (2.7%), AGO2 (2.7), AR (5.8), TP53 (-4.0%). btw. NKX3-1 (16%) any suggestions on the way to go next?
Before we discuss with MO (who replies the findings indicate continuation of SOC (
Docetaxel
+ Carboplatin), the key oncogenic markers are: ERBB3 (2.3%), MYC (2.7%), AGO2 (2.7), AR (5.8), TP53 (-4.0%). btw. NKX3-1 (16%) any suggestions on the way to go next?
julyturqsee
in
Advanced Prostate Cancer
2 years ago
Trial: Docetaxel in combination with DKN-01
Has any one had experience with this form of therapy with DKN-01 monoclonal antibody and
Docetaxel
to treat advance PCa patients with elevated DKK1?
Has any one had experience with this form of therapy with DKN-01 monoclonal antibody and
Docetaxel
to treat advance PCa patients with elevated DKK1?
Back2future
in
Advanced Prostate Cancer
3 years ago
Lymphoedema with MBC
I am currently halfway through my chemo - I have had three cycles of
Docetaxel
(plus Phesgo) with three to go. I've had a lot of horrible side-effects but am persevering.
I am currently halfway through my chemo - I have had three cycles of
Docetaxel
(plus Phesgo) with three to go. I've had a lot of horrible side-effects but am persevering.
Ursula_I
in
SHARE Metastatic Breast Cancer
2 years ago
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