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Degarelix
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Second hormone therapy drug- decision needed-any views?
My 'triple' initial plan for my PCa which spread to the spine and rib last year has already changed from:
Degarelix
LU-177 (personal choice to replace chemo though i am hormone sensitive Abitraterone to
Degarelix
Lu-177 x 3 plus Chemo x 3 ( Onco recommendation) Second hormone therapy drug I have been
My 'triple' initial plan for my PCa which spread to the spine and rib last year has already changed from:
Degarelix
LU-177 (personal choice to replace chemo though i am hormone sensitive Abitraterone to
Degarelix
Lu-177 x 3 plus Chemo x 3 ( Onco recommendation) Second hormone therapy drug I have been
Brysonal
in
Advanced Prostate Cancer
2 years ago
Please weigh in on Treatment Plan
Aggarwal's Androgen Annihilation trial for 1 year (
Degarelix
+ Abiraterone + Apalutamide + Prednison). He stayed non-detectable for 1 year post trial and now, but PSA has been on the rise. The last PSMA scan found 1 small avid lesion on his pelvic bone for which he had SBRT.
Aggarwal's Androgen Annihilation trial for 1 year (
Degarelix
+ Abiraterone + Apalutamide + Prednison). He stayed non-detectable for 1 year post trial and now, but PSA has been on the rise. The last PSMA scan found 1 small avid lesion on his pelvic bone for which he had SBRT.
Jlgjdf
in
Advanced Prostate Cancer
2 years ago
Unfortunate News precipitated by rare side effect of Docetaxl
He was diagnosed with Stage 4 Prostate cancer in June 2020 and started ADT (Arbiraterone +
Degarelix
(monthly) + Denosumab (Quarterly)) soon after. His cancer became Castration Resistant starting May 2021 (PSA doubling time around a month) and he insisted starting chemotherapy soon.
He was diagnosed with Stage 4 Prostate cancer in June 2020 and started ADT (Arbiraterone +
Degarelix
(monthly) + Denosumab (Quarterly)) soon after. His cancer became Castration Resistant starting May 2021 (PSA doubling time around a month) and he insisted starting chemotherapy soon.
doklam2017
in
Advanced Prostate Cancer
2 years ago
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Archive tumour genomic sequencing test advice needed.
Degarelix
- started 25th November 2021 Early Lu-177 ( off licience) 2 infusions with third planned for 10th Feb Abiraterone not started yet My PSA is now 0.79 but no PSMA scan yet.
Degarelix
- started 25th November 2021 Early Lu-177 ( off licience) 2 infusions with third planned for 10th Feb Abiraterone not started yet My PSA is now 0.79 but no PSMA scan yet.
Brysonal
in
Advanced Prostate Cancer
2 years ago
Fathers update:
Psa 1600 Started
degarelix
. Psa down to 16 before docetaxel Monthly hormone injections now replaced by quarterly injections Before 5th dose of chemo Psa down to 0.3 One more dose of chemo to go and then we will have to see what the new year brings.
Psa 1600 Started
degarelix
. Psa down to 16 before docetaxel Monthly hormone injections now replaced by quarterly injections Before 5th dose of chemo Psa down to 0.3 One more dose of chemo to go and then we will have to see what the new year brings.
Jordanh97
in
Advanced Prostate Cancer
2 years ago
Real-world Cardiovascular Outcomes Associated With Degarelix vs Leuprolide
Real-world Cardiovascular Outcomes Associated With
Degarelix
vs Leuprolide for Prostate Cancer Treatment An interesting study that concludes there is no difference in cardio impact between the two drugs. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2785385
Real-world Cardiovascular Outcomes Associated With
Degarelix
vs Leuprolide for Prostate Cancer Treatment An interesting study that concludes there is no difference in cardio impact between the two drugs. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2785385
Don_1213
in
Advanced Prostate Cancer
3 years ago
Rising PSA after chemo, next steps?
Started
degarelix
, had 6 sessions of docetaxel, added abiraterone in August, consolidative SBRT in September. Lowest PSA was 0.99 right after chemo, in August. In September, 1.12, October 1.87, and now in November it is 4.16. His Testosterone levels remain <7. (Switched to Orgovyx 6 weeks ago.)
Started
degarelix
, had 6 sessions of docetaxel, added abiraterone in August, consolidative SBRT in September. Lowest PSA was 0.99 right after chemo, in August. In September, 1.12, October 1.87, and now in November it is 4.16. His Testosterone levels remain <7. (Switched to Orgovyx 6 weeks ago.)
leebeth
in
Advanced Prostate Cancer
2 years ago
Orgovyx pharmacy availability
My husband is being switched from
degarelix
to Orgovyx. Walgreen’s doesn’t carry it. His oncologist ordered it from a specialty pharmacy called Biologics but it has not arrived, and he is supposed to start it today. For those of you already taking Orgovyx, which pharmacy did you use?
My husband is being switched from
degarelix
to Orgovyx. Walgreen’s doesn’t carry it. His oncologist ordered it from a specialty pharmacy called Biologics but it has not arrived, and he is supposed to start it today. For those of you already taking Orgovyx, which pharmacy did you use?
bethdavis
in
Advanced Prostate Cancer
3 years ago
Changing treatments?
I have been on Firmagon (
Degarelix
) for 6 months now & have had success with it bringing the PSA down from 18.6 to 0.7 & now the ONC wants to change to Zoladex but am worried about different side effects. Is there any worse side effects?
I have been on Firmagon (
Degarelix
) for 6 months now & have had success with it bringing the PSA down from 18.6 to 0.7 & now the ONC wants to change to Zoladex but am worried about different side effects. Is there any worse side effects?
ARIES29
in
Advanced Prostate Cancer
2 years ago
Need help asap
Had one
Degarelix
just before the MRI and a surgical castration since. Seems like after each test, his dementia is worse. Should I ask he wait on the scans until a treatment is in place?
Had one
Degarelix
just before the MRI and a surgical castration since. Seems like after each test, his dementia is worse. Should I ask he wait on the scans until a treatment is in place?
Pops78
in
Advanced Prostate Cancer
3 years ago
1st Post - Still in shock...
Immediately after surgery I was given an injection of
Degarelix
which I have continued monthly. In July my PSA had dropped to 12. I go again next week. The Oncologist is content to just continue the
Degarelix
and monitor the PSA level. I'm 59 and was very fit and active.
Immediately after surgery I was given an injection of
Degarelix
which I have continued monthly. In July my PSA had dropped to 12. I go again next week. The Oncologist is content to just continue the
Degarelix
and monitor the PSA level. I'm 59 and was very fit and active.
davidw777
in
Advanced Prostate Cancer
3 years ago
Zytiga - Abiraterone - To take or not to take right now
We initiated treatment the first week in January 2021 with double injections of
Degarelix
and started chemo with Docetaxel. After 30 days I was switched to Lupron which now I have received every 3 months.
We initiated treatment the first week in January 2021 with double injections of
Degarelix
and started chemo with Docetaxel. After 30 days I was switched to Lupron which now I have received every 3 months.
MoZee
in
Advanced Prostate Cancer
3 years ago
what should next step be? Heads spinning with conflicting and confusing info. and medical advice
] graded it 4 + 4=8 GL8 and Grade Grade 4 Adenocarcinoma with Cribriform pattern 4 3-T MRI noted
Pi-Rads 4
Started on ADT 1/28:
Jan-
Degarelix
] graded it 4 + 4=8 GL8 and Grade Grade 4 Adenocarcinoma with Cribriform pattern 4 3-T MRI noted
Pi-Rads 4
Started on ADT 1/28:
Jan-
Degarelix
KAgolf
in
Advanced Prostate Cancer
3 years ago
PSA IS BACK
Multiple osseous sclerotic lesions • Started on
Degarelix
and Denosumab (1 July 2020) • MRI LS spine: Multiple metastatic focal lesions in LS vertebrae and bilateral iliac bones. •Dexa Scan done on 20 October 2020: Normal T score-2.9.
Multiple osseous sclerotic lesions • Started on
Degarelix
and Denosumab (1 July 2020) • MRI LS spine: Multiple metastatic focal lesions in LS vertebrae and bilateral iliac bones. •Dexa Scan done on 20 October 2020: Normal T score-2.9.
doklam2017
in
Advanced Prostate Cancer
3 years ago
Regional or metastatic? Proton + ADT +???
PSA was 3.7 in 9/2019, 5.15 in 9/20, 8.18 in 12/20, and 10.43 before
Degarelix
injection 1/28/21.
PSA was 3.7 in 9/2019, 5.15 in 9/20, 8.18 in 12/20, and 10.43 before
Degarelix
injection 1/28/21.
KAgolf
in
Advanced Prostate Cancer
3 years ago
Looking for hope and Inspiration from your stories.
He had two hormone injections 2 weeks ago (
degarelix
) . I plan on getting more information on treatments after his biopsy results come through. Which he had on the same day as he started his HT. I led to believe he will have this HT alongside Chemo.
He had two hormone injections 2 weeks ago (
degarelix
) . I plan on getting more information on treatments after his biopsy results come through. Which he had on the same day as he started his HT. I led to believe he will have this HT alongside Chemo.
Jordanh97
in
Advanced Prostate Cancer
3 years ago
Firmagon (Degarelix) injections - my nurse's tricks
One fellow here had reported problems at his injection site, due to Firmagon (
Degarelix
). I have these injections monthly in my stomach area, and I don't have such big problems; so last week, I asked my nurse, "What are your tricks?"
One fellow here had reported problems at his injection site, due to Firmagon (
Degarelix
). I have these injections monthly in my stomach area, and I don't have such big problems; so last week, I asked my nurse, "What are your tricks?"
A0007720
in
Advanced Prostate Cancer
3 years ago
IMPROVED RESPONSE TO ADT thanks to you all and your feedback
Switched from 6-month Lupron depot shots to monthly
Degarelix
shots. (
Degarelix
is only available in 1 month shots).
Degarelix
does NOT give me the brain fog that Lupron used to give. Increased my Lexapro (depression medicine) from 10 mg to 20 mg daily. Exercising 6 days per week, instead of 4.
Switched from 6-month Lupron depot shots to monthly
Degarelix
shots. (
Degarelix
is only available in 1 month shots).
Degarelix
does NOT give me the brain fog that Lupron used to give. Increased my Lexapro (depression medicine) from 10 mg to 20 mg daily. Exercising 6 days per week, instead of 4.
A0007720
in
Advanced Prostate Cancer
3 years ago
Muscle pain from ADT
I am using Firmagon/
degarelix
. In one study, albeit a bit dated it´s from 2011 havn´t found anything newer, Leuprolide is found to give less body pain than Firmagon with a p-value of just 0.006.
I am using Firmagon/
degarelix
. In one study, albeit a bit dated it´s from 2011 havn´t found anything newer, Leuprolide is found to give less body pain than Firmagon with a p-value of just 0.006.
Purple-Bike
in
Advanced Prostate Cancer
3 years ago
Best ways for dealing with ADT side effects?
I've been on ADT for 14 3/4 months. (1st month was
Degarelix
, then 12 months Lupron, now back to
Degarelix
). I want to try to reach 24 months of ADT. I know of the Nabid study thanks to Tall (Heroic, Generous, Knowledgeable) Allen, but want to attain 2 years minimum of ADT.
I've been on ADT for 14 3/4 months. (1st month was
Degarelix
, then 12 months Lupron, now back to
Degarelix
). I want to try to reach 24 months of ADT. I know of the Nabid study thanks to Tall (Heroic, Generous, Knowledgeable) Allen, but want to attain 2 years minimum of ADT.
A0007720
in
Prostate Cancer Network
3 years ago
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