Experiences with

Crizotinib

Kindly guide what precautions should I take while Crizotinib and what About the phlegm cough that I have.

Kindly guide what precautions should I take while Crizotinib and what About the phlegm cough that I have. Is it ok ..

His drug, crizotinib, made by Pfizer, has a list price of $20,000 a month. Mr. Catlin’s co-payment is $1,000 a month. But, he says, “it’s keeping me alive.” “It’s almost surreal,” Mr. Catlin said. ❤️🙏❤️

The abstract “Patient-reported outcomes from the randomized Phase 3 CROWN study of first-line lorlatinib versus crizotinib in ALK+ NSCLC” by Mazieres et al., presents a welcome analysis of symptoms and health-related quality of life (QOL) in those patients receiving the ALK inhibitors crizotinib vs.

The FDA based their approval on the results of a clinical trial which found that patients receiving Lobrena went longer before experiencing progression than those who received Xalkori (crizotinib).

The FDA based their approval on the results of the clinical trial ALTA 1L which showed that patients receiving Alunbrig (brigatinib) had a higher chance of responding well to treatment, and went longer periods of time without progression than those receiving Xalkori (crizotinib).

It has been shown that the crizotinib induces alterations in the secretome of the melanoma cells contributing to the emergence and expansion of the resistant subpopulations [86].

The NHS oncologist we are seeing wants to prescribe Crizotinib but I have been reading that Alectinib is now the new standard for first line treatment. Any thoughts on this would be much appreciated - is it the case that Crizotinib is still okay?

will be assessed under is: "As monotherapy is indicated for the treatment of adult patients with anaplastic lymphoma kinase (ALK) positive advanced non-small cell lung cancer (NSCLC) whose disease has progressed after: Alectinib or ceritinib as the first ALK tyrosine kinase inhibitor (TKI) therapy; or Crizotinib

Hi iv just started on crizotinib on a trial and at the moment on cyclizine for sickness...Just woundering if anyone has any views comments help ect on either...thank you...good luck to all.

The targeted drug, Crizotinib, isn’t working so the cancer is now in my pelvis and back as well as the foot of the spine. I’ve to get 5 sessions of radiotherapy there because of the pain and I’m practically bedbound.

Lorlatinib possibly next if available: anyone with success with this or possibly Crizotinib/ Pem if CT stable or better. Thought Pem would last longer in ROS 1. Still a way to go but such a roller coaster ( not the nice kind).

I have just had compassionate access to it after only 7 months on crizotinib. I now have brain tumours as crizotinib does not protect the brain. We need to try and get NICE to change their policy and use 2nd generation drugs as firstline treatments as they do in the usa.

Oncologists obviously realise it's the best 1st line treatment or she would have been put on Crizotinib which is approved!!! Breaks my heart for newly diagnosed AlKIES denied this wonder drug

Am I allowed to give my deceased fathers Crizotinib away? It costs thousands and I have almost a full bottle of it. Seems like a real waste to just throw it away. It expires in 2019.

My husband is about to change from crizotinib to ceritinib and I was wondering if anyone else had done this. I would be grateful for any advice on side effects, effectiveness etc of ceritinib and how it compares to crizotinib.

Hi everyone I am 55 months non smoker with stage4 NSCC I have been on crizotinib all treatment for 4 weeks. I believe it's got a 60 percent success figure which is good. Does anyone know of anyone who found it didn't work for them and how long it took to find out? So far very minor side effects.

My daughter Kay age 19 has been on crizotinib 3/12 months now. Latest ct scan reduced/invisible lesions and reduced/ not detectable lymph nodes right lung and no detectable lung cancer left lung!!! She started Sheffield Hallam studying nursing in September. She is my inspiration!!

I have been put on crizotinib for a year. I am single two daughters and worried about ever getting back to work again. Who will accept me with this medical condition ?How hard is it to get work with cancer? Are there any other teachers out there going through the same worries?.

I was doing well for 6 months with a targeted drug (crizotinib for ALK-positive mutation) but about 3 weeks ago began feeling very ill again, tired, not wanting to do anything, sickish, food/drinks tasting horrible etc. Any help on what I might do?