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Brukinsa
Just started taking, First 3 days were very rough. Not so bad now. Anyone else taking it?
Just started taking, First 3 days were very rough. Not so bad now. Anyone else taking it?
xv750
in
CLL Support
7 months ago
Brukinsa/Zanubrutinib slow working at present time
I started treatment in early May with Zanubrutinib but because of severe stomach pain with it and acyclovir stopped it after 6 weeks so that an endoscopy could be done. Wbc started at 212,000 and went up to 300,000 in 2 1/2 weeks. 2 weeks later down to 165,000. The time off was almost 3 weeks. Started
I started treatment in early May with Zanubrutinib but because of severe stomach pain with it and acyclovir stopped it after 6 weeks so that an endoscopy could be done. Wbc started at 212,000 and went up to 300,000 in 2 1/2 weeks. 2 weeks later down to 165,000. The time off was almost 3 weeks. Started
Bethsaida
in
CLL Support
1 year ago
Calquence / acalabrutinib and Brukinsa / zanubrutinib Adverse Event Comparison for Chronic Lymphocytic Leukaemia / CLL from clinical trials
Now that we have a growing choice of BTK inhibitor treatment options, naturally the question is which one is better? Based on this meta-analysis study of the incidence of 84 Adverse Events (AEs) reported in 61 clinical trials involving nearly 7,000 patients, that question should be better framed as
Now that we have a growing choice of BTK inhibitor treatment options, naturally the question is which one is better? Based on this meta-analysis study of the incidence of 84 Adverse Events (AEs) reported in 61 clinical trials involving nearly 7,000 patients, that question should be better framed as
AussieNeil
Partner
in
CLL Support
1 year ago
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Is thyroid hormone replacement allowed to take when you are on a BTK inhibitor?
I'm wondering if anyone in this group is under treatment with the new generation of BTK inhibitor/
Brukinsa
/ Zanubrutiniband is still able to take levothyroxine and T3 with no change in thyroid blood results.? Thanks for your help.
I'm wondering if anyone in this group is under treatment with the new generation of BTK inhibitor/
Brukinsa
/ Zanubrutiniband is still able to take levothyroxine and T3 with no change in thyroid blood results.? Thanks for your help.
sunsetssr
in
CLL Support
1 year ago
Anyone with AF got any experience with taking either Zanubrutinib or R&V
Initially my consultant was happy to start me on Zanubrutinib (
Brukinsa
) the following day but subsequently he called me to tell me that following discussions with his other CLL colleagues their advice was that because of my AF then the R&V treatment would be a less riskier and more suitable option.
Initially my consultant was happy to start me on Zanubrutinib (
Brukinsa
) the following day but subsequently he called me to tell me that following discussions with his other CLL colleagues their advice was that because of my AF then the R&V treatment would be a less riskier and more suitable option.
Ageon
in
CLL Support
7 months ago
Blurred vision with Zanubrutinib (Brukinsa)
I wonder whether anybody who has been taking the recently-approved drug Zanubrutinib (
Brukinsa
) has experienced blurred vision? I started on the drug two months ago after having been obliged to stop Ibrutinib because it caused an ocular edema, the symptom of which was blurred vision.
I wonder whether anybody who has been taking the recently-approved drug Zanubrutinib (
Brukinsa
) has experienced blurred vision? I started on the drug two months ago after having been obliged to stop Ibrutinib because it caused an ocular edema, the symptom of which was blurred vision.
Snoopy234
in
CLL Support
2 years ago
Treatment-naive or relapsed CLL patients will soon have zanubrutinib/Brukinsa as a treatment option in the EU
vs 78%.i The adverse events within the two trials were consistent with the overall safety profile of
BRUKINSA
.
vs 78%.i The adverse events within the two trials were consistent with the overall safety profile of
BRUKINSA
.
AussieNeil
Partner
in
CLL Support
2 years ago
Medicare plans
I take
Brukinsa
now and will probably be needing other expensive medications at some point. Thank you.
I take
Brukinsa
now and will probably be needing other expensive medications at some point. Thank you.
kesslm
in
CLL Support
2 years ago
COVID: Staying Safe As The Virus Evolves - LLS Podcast / CLL Society’s COVID-19 Update December 5th, 2022 / Dec 15 2022 end Antibody Study
These include: • Bruton tyrosine kinase (BTK) inhibitors, such as Imbruvica® (ibrutinib),
Brukinsa
® (zanubrutinib) and Calquence® (acalabrutinib) • Anti-CD20 antibody treatments, such as Rituxan® (rituximab) and Gazyva® (obinutuzumab) • CD-19 targeting CAR T-therapy (Breyanzi®, Kymriah®, Tecartus™
These include: • Bruton tyrosine kinase (BTK) inhibitors, such as Imbruvica® (ibrutinib),
Brukinsa
® (zanubrutinib) and Calquence® (acalabrutinib) • Anti-CD20 antibody treatments, such as Rituxan® (rituximab) and Gazyva® (obinutuzumab) • CD-19 targeting CAR T-therapy (Breyanzi®, Kymriah®, Tecartus™
lankisterguy
Volunteer
in
CLL Support
2 years ago
COVID update: Who remains at higher risk? by LLS.org
These include: • Bruton tyrosine kinase (BTK) inhibitors, such as Imbruvica® (ibrutinib),
Brukinsa
® (zanubrutinib) and Calquence® (acalabrutinib) • Anti-CD20 antibody treatments, such as Rituxan® (rituximab) and Gazyva® (obinutuzumab) • CD-19 targeting CAR T-therapy (Breyanzi®, Kymriah®, Tecartus™
These include: • Bruton tyrosine kinase (BTK) inhibitors, such as Imbruvica® (ibrutinib),
Brukinsa
® (zanubrutinib) and Calquence® (acalabrutinib) • Anti-CD20 antibody treatments, such as Rituxan® (rituximab) and Gazyva® (obinutuzumab) • CD-19 targeting CAR T-therapy (Breyanzi®, Kymriah®, Tecartus™
lankisterguy
Volunteer
in
CLL Support
2 years ago
FDA Approves Zanubrutinib for Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphom
The FDA has approved zanubrutinib (
Brukinsa
) for the treatment of patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). The approval was based on findings from the phase 3 SEQUOIA (NCT03336333) and ALPINE (NCT03734016) trials.
The FDA has approved zanubrutinib (
Brukinsa
) for the treatment of patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). The approval was based on findings from the phase 3 SEQUOIA (NCT03336333) and ALPINE (NCT03734016) trials.
lankisterguy
Volunteer
in
CLL Support
2 years ago
Zanubrutinib PFS, ORR Is Superior to Ibrutinib for Relapsed/Refractory CLL/SLL
utm_source=sfmc&utm_ Conference | ASH Annual Meeting and Exposition reported By Silas Inman Dec 13, 2022 Treatment with zanubrutinib (
Brukinsa
) reduced the risk of progression or death by 35% compared with ibrutinib (Imbruvica) for patients with relapsed or refractory chronic lymphocytic leukemia
utm_source=sfmc&utm_ Conference | ASH Annual Meeting and Exposition reported By Silas Inman Dec 13, 2022 Treatment with zanubrutinib (
Brukinsa
) reduced the risk of progression or death by 35% compared with ibrutinib (Imbruvica) for patients with relapsed or refractory chronic lymphocytic leukemia
lankisterguy
Volunteer
in
CLL Support
2 years ago
Brukinsa for CLL
Anyone have experience with taking
Brukinsa
for Cll. I had and a fib reaction to imbruvica. My doctor got an off label exception for
brukinsa
. It has the lowest instance of a fib.
Anyone have experience with taking
Brukinsa
for Cll. I had and a fib reaction to imbruvica. My doctor got an off label exception for
brukinsa
. It has the lowest instance of a fib.
Gretsch6120
in
CLL Support
3 years ago
Red mark on my left leg like a rash. comes and goes depending on walking and ice pack. It's been 2 days.
I am taking 320mg of
Brukinsa
. Anyone experiencing this.
I am taking 320mg of
Brukinsa
. Anyone experiencing this.
brooklyn7672
in
CLL Support
3 years ago
Bloody Nose
Has anyone had nose bleeds using
Brukinsa
combined with a Covid Shot and taking Tylenol
Has anyone had nose bleeds using
Brukinsa
combined with a Covid Shot and taking Tylenol
brooklyn7672
in
CLL Support
3 years ago
Brukinsa
My wife is starting
Brukinsa
today with 1 pill 80mg in the morning and 1 at night. Please post who has been taking this and how they are doing.
My wife is starting
Brukinsa
today with 1 pill 80mg in the morning and 1 at night. Please post who has been taking this and how they are doing.
brooklyn7672
in
CLL Support
4 years ago
NEW MEDICATIONS ON THE HORIZON
In particular the article is mentioning that these two medications are likely to be huge competitors to Imbruvica (Imbrutinib) Here is a link to the article: https://www.fiercepharma.com/pharma/ash-astrazeneca-s-calquence-beigene-s-
brukinsa
-turn-heads-new-data-putting-imbruvica-notice
In particular the article is mentioning that these two medications are likely to be huge competitors to Imbruvica (Imbrutinib) Here is a link to the article: https://www.fiercepharma.com/pharma/ash-astrazeneca-s-calquence-beigene-s-
brukinsa
-turn-heads-new-data-putting-imbruvica-notice
wizzard166
in
CLL Support
4 years ago
YABTKi or Yet Another BTK inhibitor - the A to Z list of Bruton's Tyrosine Kinase Inhibitors for CLL following Ibrutinib's success
[/i]
Brukinsa
provides patients with CLL with improvements in response and reduced rates of atrial fibrillation or flutter compared to ibrutinib, in head to head comparison, funded by BeiGene, naturally! At a median follow-up of 15 mo, ORR was significantly higher with zanubrutinib vs ibrutinib.
[/i]
Brukinsa
provides patients with CLL with improvements in response and reduced rates of atrial fibrillation or flutter compared to ibrutinib, in head to head comparison, funded by BeiGene, naturally! At a median follow-up of 15 mo, ORR was significantly higher with zanubrutinib vs ibrutinib.
AussieNeil
Partner
in
CLL Support
5 years ago
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