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Bicalutamide
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Just diagnosed with Advanced Prostate Caner
Doctor started me on Trelstar and
Bicalutamide
. He also prescribed Venlafaxine to help with the hot flashes. (This step happened last week) My next appointment is in September to see if the PSA numbers have dropped at all.
Doctor started me on Trelstar and
Bicalutamide
. He also prescribed Venlafaxine to help with the hot flashes. (This step happened last week) My next appointment is in September to see if the PSA numbers have dropped at all.
TrashPanda72
in
Advanced Prostate Cancer
4 years ago
Casodex failure? What's next?
Short story: -42 yr old husband had RALP in the summer of 2017 -Undetectable until Jan of 2019 -IMRT from April-June of 2019 (in addition to
bicalutamide
which was supposed to last 2 years) -Undetectable until today (.13 - just updated my profile) We have an appt with his doc, but it’s not until next
Short story: -42 yr old husband had RALP in the summer of 2017 -Undetectable until Jan of 2019 -IMRT from April-June of 2019 (in addition to
bicalutamide
which was supposed to last 2 years) -Undetectable until today (.13 - just updated my profile) We have an appt with his doc, but it’s not until next
pwallace
in
Advanced Prostate Cancer
4 years ago
PSA rising
OC2 also suggested radiation therapy but recommended that we
continue on
, which we did. By the time radiation could start, the
PSA
levels had gone up, to
12
.
OC2 also suggested radiation therapy but recommended that we
continue on
, which we did. By the time radiation could start, the
PSA
levels had gone up, to
12
.
seeker47
in
Advanced Prostate Cancer
4 years ago
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Bicalutamide: first lab results, nadir comes when?
On 5/12/20 began meds : Bicalutimide 150 mg, Finasteride 5 mg, Tamoxifen 10 mg Background: April 2019 PSA 20 and dx w/ Gleason 3+4=7, July PSA 13, Nov. PSA 26 (and SCANS SHOW BONE METS), Feb. 2020 PSA 31. Still zero symptoms/pain. I could not find an MO to do either high-dose estradiol (first choice)
On 5/12/20 began meds : Bicalutimide 150 mg, Finasteride 5 mg, Tamoxifen 10 mg Background: April 2019 PSA 20 and dx w/ Gleason 3+4=7, July PSA 13, Nov. PSA 26 (and SCANS SHOW BONE METS), Feb. 2020 PSA 31. Still zero symptoms/pain. I could not find an MO to do either high-dose estradiol (first choice)
noahware
in
Advanced Prostate Cancer
4 years ago
My dad has advanced cancer
It started with the hormonal block in February: monthly Goserelin injections and daily
Bicalutamide
. In March, its psa fell to 10.17 and in May to 2.10. Against this background, we have thousands of opinions. Urologists tell us that evolution is favorable and that it continue like this.
It started with the hormonal block in February: monthly Goserelin injections and daily
Bicalutamide
. In March, its psa fell to 10.17 and in May to 2.10. Against this background, we have thousands of opinions. Urologists tell us that evolution is favorable and that it continue like this.
azulmsalas
in
Advanced Prostate Cancer
4 years ago
Bicalutamide not working any more!
History: Advanced prostate cancer: Removed prostate and 25 lymph notes in 2018 (gleason 9), but PSA was still rising after the operation and got on
bicalutamide
, which now has stoped working.
History: Advanced prostate cancer: Removed prostate and 25 lymph notes in 2018 (gleason 9), but PSA was still rising after the operation and got on
bicalutamide
, which now has stoped working.
Jurasuje
in
Advanced Prostate Cancer
4 years ago
Question on Bicalutamide Withdrawal
There is evidence that when you are on Lupron and
Bicalutamide
for metastatic prostate cancer and your PSA starts rising, stopping
Bicalutamide
may, in some cases, lead to drop in PSA. In my case, I was on Lupron +
Bicalutamide
for one year for metastatic prostate cancer.
There is evidence that when you are on Lupron and
Bicalutamide
for metastatic prostate cancer and your PSA starts rising, stopping
Bicalutamide
may, in some cases, lead to drop in PSA. In my case, I was on Lupron +
Bicalutamide
for one year for metastatic prostate cancer.
dac500
in
Advanced Prostate Cancer
4 years ago
MY PSA RESULT
Hi Good People I stopped taking
Bicalutamide
150mg Date 30/10/2019 I did psa test 18/02/2020 it was 0.16 I did anothwer psa test 13/05/2020 it was 0.4 I need from you good people to give advise. Thanks Regards from sweden George
Hi Good People I stopped taking
Bicalutamide
150mg Date 30/10/2019 I did psa test 18/02/2020 it was 0.16 I did anothwer psa test 13/05/2020 it was 0.4 I need from you good people to give advise. Thanks Regards from sweden George
NOCanceros
in
Advanced Prostate Cancer
4 years ago
High Testosterone after one month Leuprolide shot
His PSA come from more than 50 to 22, but I guess is only because
Bicalutamide
. His alkaline phosphatase is on 75. His platalets come from 100 to 220, but his Hemoglobine levels are still low with 11.2. Do You know what can we do in this case? Wait? A new shot?
His PSA come from more than 50 to 22, but I guess is only because
Bicalutamide
. His alkaline phosphatase is on 75. His platalets come from 100 to 220, but his Hemoglobine levels are still low with 11.2. Do You know what can we do in this case? Wait? A new shot?
olloreda
in
Advanced Prostate Cancer
4 years ago
Update
Was prescribed
bicalutamide
which he immediately started and is going in for a shot (not to sure which one) In a weeks time.
Was prescribed
bicalutamide
which he immediately started and is going in for a shot (not to sure which one) In a weeks time.
Nicholas27
in
Advanced Prostate Cancer
4 years ago
Is it crpc after 22 months of diagnose?
My psa has risen from 0.08 on 4 Jan 2020 to 0.972 ng/dl on 23 Rd april 2020 with testosterone level 9..I am on
bicalutamide
50 mg od frm last 22 month..psa at time of diagnosis was 111ng/dl ; Gleason score was 3+4; and was metastized to inferior iliac spine at the time of diagnosis, no new spots of Mets
My psa has risen from 0.08 on 4 Jan 2020 to 0.972 ng/dl on 23 Rd april 2020 with testosterone level 9..I am on
bicalutamide
50 mg od frm last 22 month..psa at time of diagnosis was 111ng/dl ; Gleason score was 3+4; and was metastized to inferior iliac spine at the time of diagnosis, no new spots of Mets
Rafithussain
in
Advanced Prostate Cancer
4 years ago
Trying to Make Sense of Husbands Testosterone History and Wanting to Clarify Why a Doctor Feels He May Be Becoming CR.
It seemed strange to be to have Provenge recommended at this stage when the only medication Charlie has ever had are Lupron and 30 days of
Bicalutamide
. Having said that, Charlie takes 2500 mg of Metformin.
It seemed strange to be to have Provenge recommended at this stage when the only medication Charlie has ever had are Lupron and 30 days of
Bicalutamide
. Having said that, Charlie takes 2500 mg of Metformin.
paige20180
in
Advanced Prostate Cancer
4 years ago
My father's metastatic cancer, a new challenge
Luckily the Leuprolide and
Bicalutamide
treatment are SOC and, therefore, given for free, but his MO suggested me to find a way to put him on Abiraterone treatment, since I know my father wouldnt agree to try Docexatel in this moment.
Luckily the Leuprolide and
Bicalutamide
treatment are SOC and, therefore, given for free, but his MO suggested me to find a way to put him on Abiraterone treatment, since I know my father wouldnt agree to try Docexatel in this moment.
olloreda
in
Advanced Prostate Cancer
4 years ago
Told to discontinue Casodex (Bicalutamide)
My dad was put on Casodex for 3 months immediately post-chemo. So he was on Lupride + Casodex. Today we got his 3-monthly blood work reviewed, the MO has instructed to stop Casodex and continue with only Lupride and get back again after 3 months with blood reports. Jan (after chemo): PSA: 0.04, ALP
My dad was put on Casodex for 3 months immediately post-chemo. So he was on Lupride + Casodex. Today we got his 3-monthly blood work reviewed, the MO has instructed to stop Casodex and continue with only Lupride and get back again after 3 months with blood reports. Jan (after chemo): PSA: 0.04, ALP
Cheerr
in
Advanced Prostate Cancer
4 years ago
Should PSA be checked during hormone treatment while waiting for radiation?
In October, he was started on Lupron shots and then
bicalutamide
. The plan is to have radiation, but it has not yet been started because he had to have two other unrelated surgeries first.
In October, he was started on Lupron shots and then
bicalutamide
. The plan is to have radiation, but it has not yet been started because he had to have two other unrelated surgeries first.
BattleMountain
in
Advanced Prostate Cancer
4 years ago
Abiraterone Withdrawal Syndrome - anyone experience it?
I'm familiar with
bicalutamide
withdrawal syndrome: PSA increases after a while taking Casodex but goes down when Casodex is stopped. This is caused by the Androgen Receptor using
bicalutamide
to become activated, and is well known. I've even seen reports of this occurring with Xtandi (see below).
I'm familiar with
bicalutamide
withdrawal syndrome: PSA increases after a while taking Casodex but goes down when Casodex is stopped. This is caused by the Androgen Receptor using
bicalutamide
to become activated, and is well known. I've even seen reports of this occurring with Xtandi (see below).
Tall_Allen
in
Advanced Prostate Cancer
4 years ago
Epigenetic Therapy with Panobinostat Combined with Bicalutamide Rechallenge in Castration-Resistant Prostate Cancer.
The primary endpoint was to determine the percentage of radiographic progression-free (rPF) patients at 36 weeks versus historic high-dose
bicalutamide
. RESULTS: In the model, panobinostat/
bicalutamide
demonstrated synergistic antitumor effect while reducing AR activity.
The primary endpoint was to determine the percentage of radiographic progression-free (rPF) patients at 36 weeks versus historic high-dose
bicalutamide
. RESULTS: In the model, panobinostat/
bicalutamide
demonstrated synergistic antitumor effect while reducing AR activity.
JLS1
in
Advanced Prostate Cancer
4 years ago
Dr. Schellhammer's own PC experience and thoughts
In 2008 with a testosterone level within the castrate range, and with a PSA on the rise after trial of
bicalutamide
withdrawal, I was searching for other options. There was no Level 1 evidence to support any pharmaceutical therapy at that time and unfortunately that remains true to this day."
In 2008 with a testosterone level within the castrate range, and with a PSA on the rise after trial of
bicalutamide
withdrawal, I was searching for other options. There was no Level 1 evidence to support any pharmaceutical therapy at that time and unfortunately that remains true to this day."
noahware
in
Advanced Prostate Cancer
4 years ago
Flutamide, bicalutamide, nilutamide, apalutamide or enzalutamide?
The combo I'm using is finasteride, tamsulosin and
bicalutamide
, which has kept my PSA <0.1 -- I've been told this cannot last but have seen enough evidence against that to give me pause. Should bical. fail anyway, which -utamide would you choose?
The combo I'm using is finasteride, tamsulosin and
bicalutamide
, which has kept my PSA <0.1 -- I've been told this cannot last but have seen enough evidence against that to give me pause. Should bical. fail anyway, which -utamide would you choose?
RICH22
in
Advanced Prostate Cancer
4 years ago
BAT final report (until the next one).
However response to rechallenge by bical was quite large (greater than original) but short lived, which perhaps suggests that my pre-BAT cancer already had a population of bical resistant cells, before any had even been exposed to
bicalutamide
. Interesting.
However response to rechallenge by bical was quite large (greater than original) but short lived, which perhaps suggests that my pre-BAT cancer already had a population of bical resistant cells, before any had even been exposed to
bicalutamide
. Interesting.
kaptank
in
Advanced Prostate Cancer
4 years ago
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