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Bicalutamide
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Anyone had experience of VMAT (RapidArc) treatment?
Started formal treatment in December 18 – advised that cancer was Locally Advanced - Treatment started with 3 weeks of
Bicalutamide
then overlapped with Lupron with a one month injection late December and a 3 month injection in late January.
Started formal treatment in December 18 – advised that cancer was Locally Advanced - Treatment started with 3 weeks of
Bicalutamide
then overlapped with Lupron with a one month injection late December and a 3 month injection in late January.
StuartS
in
Prostate Cancer Network
5 years ago
Please shoot holes in this plan.
Dx Stage 4 Gl 9 bone mets only, PSA 41, 6 cy. docataxel, leuprolide since 10/16, PSA 1.2, doubled in a year, added
bicalutamide
, doubled in a year, swapped out Casodex for enzalutamide, roughly half way through the Provenge thang.
Dx Stage 4 Gl 9 bone mets only, PSA 41, 6 cy. docataxel, leuprolide since 10/16, PSA 1.2, doubled in a year, added
bicalutamide
, doubled in a year, swapped out Casodex for enzalutamide, roughly half way through the Provenge thang.
Crabcrushe
in
Advanced Prostate Cancer
5 years ago
Newly diagnosed and full of questions
The surgeon said he doesn't usually bother with hormone therapy before the op, but "in my case" he would prescribe
Bicalutamide
, which I've just started.
The surgeon said he doesn't usually bother with hormone therapy before the op, but "in my case" he would prescribe
Bicalutamide
, which I've just started.
GreenBloke
in
Prostate Cancer Network
5 years ago
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CBD effects apoptosis in all 4 PCa cell lines -- significantly enhanced the anti‐cancer effects of bicalutamide
In these tumours, CBD also significantly enhanced the anti‐cancer effects of
bicalutamide
(extending the survival time of the animals), but not those of docetaxel.
In these tumours, CBD also significantly enhanced the anti‐cancer effects of
bicalutamide
(extending the survival time of the animals), but not those of docetaxel.
George71
in
Advanced Prostate Cancer
5 years ago
Thoughts on BAT
I have concluded that it has reversed the resistance that had built up to ADT (gnhr agonist zolodex) +
bicalutamide
(Casodex). Its about 6 months since I rechallenged the beast with
bicalutamide
after PSA started rising at the end of the BAT.
I have concluded that it has reversed the resistance that had built up to ADT (gnhr agonist zolodex) +
bicalutamide
(Casodex). Its about 6 months since I rechallenged the beast with
bicalutamide
after PSA started rising at the end of the BAT.
kaptank
in
Advanced Prostate Cancer
5 years ago
Am I on track?
I commenced Hormone therapy
Bicalutamide
tabs 50mg, mid December for 3 weeks, and had my first (one month dose) of Leuprorelin (L) 3.75mg on 28th Dec 18. Received second L injection on 25th Jan 19 which was a 3 month dose.
I commenced Hormone therapy
Bicalutamide
tabs 50mg, mid December for 3 weeks, and had my first (one month dose) of Leuprorelin (L) 3.75mg on 28th Dec 18. Received second L injection on 25th Jan 19 which was a 3 month dose.
StuartS
in
Advanced Prostate Cancer
5 years ago
Testosterone level too high
Currently I am on hormone therapy with 50mg
Bicalutamide
per day and 20 mg Tamoxifen. Plus 850 mg Metformin. Any suggestions what is causing this testosterone level and what I should do?
Currently I am on hormone therapy with 50mg
Bicalutamide
per day and 20 mg Tamoxifen. Plus 850 mg Metformin. Any suggestions what is causing this testosterone level and what I should do?
GP24
in
Advanced Prostate Cancer
5 years ago
Niclosamide and Bicalutamide CombinationTreatment Overcomes Enzalutamide- andBicalutamide-Resistant Prostate Cancer
http://mct.aacrjournals.org/content/molcanther/16/8/1521.full.pdf In summary, our results demonstrate that AR variants, particularly AR-V7, drive
bicalutamide
resistance. Targeting AR-V7 with niclosamide can resensitize
bicalutamide
-resistant cells to
bicalutamide
treatment.
http://mct.aacrjournals.org/content/molcanther/16/8/1521.full.pdf In summary, our results demonstrate that AR variants, particularly AR-V7, drive
bicalutamide
resistance. Targeting AR-V7 with niclosamide can resensitize
bicalutamide
-resistant cells to
bicalutamide
treatment.
traveller64
in
Advanced Prostate Cancer
5 years ago
Why I'm here Part 2
Dumb, but I ain't got time to dwell\snivel about the past, so when the the
bicalutamide
failed after about a year and the good Doctor offered the Provenge, I was on it like a duck on a June bug and requested the enzalutamide.
Dumb, but I ain't got time to dwell\snivel about the past, so when the the
bicalutamide
failed after about a year and the good Doctor offered the Provenge, I was on it like a duck on a June bug and requested the enzalutamide.
Crabcrushe
in
Advanced Prostate Cancer
5 years ago
PSMA Scan and HU Altered my Treatment Plan
Treatment Plan: Started
Bicalutamide
today and will receive my Lupron shot in 30 days. I have sent an email to my MO asking for abiraterone to be added to complete the ADT treatment. I am not confident that my MO will allow the abiraterone but am hopeful.
Treatment Plan: Started
Bicalutamide
today and will receive my Lupron shot in 30 days. I have sent an email to my MO asking for abiraterone to be added to complete the ADT treatment. I am not confident that my MO will allow the abiraterone but am hopeful.
Moespy
in
Advanced Prostate Cancer
5 years ago
Wanted to share some positive news
He started Zolodex which worked well for 2 years, PSA staying at 1.5,
Bicalutamide
was added when PSA started to rise and that worked well for another year.
He started Zolodex which worked well for 2 years, PSA staying at 1.5,
Bicalutamide
was added when PSA started to rise and that worked well for another year.
LB100
in
Advanced Prostate Cancer
5 years ago
Thoughts on Afinator and Bicalutamide-Everolimus
I would love to get your thoughts on taking the combination of Afinator with
Bicalutamide
-Everolimus for prostate cancer.
I would love to get your thoughts on taking the combination of Afinator with
Bicalutamide
-Everolimus for prostate cancer.
TL1111
in
Advanced Prostate Cancer
5 years ago
seeking advice
We will receive diagnoses in two weeks and in the meanwhile doctor has prescribe Casodex
bicalutamide
. My question is will it be okay for my father to continue smoking medical marijuana/oil while taking chemo therapy pills. It really helps with pain and he doesn’t want to take norcos.
We will receive diagnoses in two weeks and in the meanwhile doctor has prescribe Casodex
bicalutamide
. My question is will it be okay for my father to continue smoking medical marijuana/oil while taking chemo therapy pills. It really helps with pain and he doesn’t want to take norcos.
Mrsram
in
Advanced Prostate Cancer
5 years ago
Casodex & metformin
: Join A Clinical Trial: Casodex (
bicalutamide
) + Metformin Dr.
: Join A Clinical Trial: Casodex (
bicalutamide
) + Metformin Dr.
Ahk1
in
Advanced Prostate Cancer
5 years ago
Phase 3 ARCHES trial - Enzalutamide + ADT
In the
bicalutamide
-controlled study of chemotherapy-naïve mCRPC patients, Grade 3-4 adverse reactions were reported in 39% of XTANDI patients and 38% of
bicalutamide
patients. Discontinuations with an AE as the primary reason were reported for 8% of XTANDI patients and 6% of
bicalutamide
patients.
In the
bicalutamide
-controlled study of chemotherapy-naïve mCRPC patients, Grade 3-4 adverse reactions were reported in 39% of XTANDI patients and 38% of
bicalutamide
patients. Discontinuations with an AE as the primary reason were reported for 8% of XTANDI patients and 6% of
bicalutamide
patients.
pjoshea13
in
Advanced Prostate Cancer
5 years ago
Calling all PC nerds: Facts/opinions/views on Zytiga (Abiraterone) metabolism?
Terminal half life is between 5-14 hours, with an average half life of ~9 hours (contrast this, dear readers, with a
Bicalutamide
half life of 5.9 days)... this would seem to indicate 2x per day rather than the 1x per day dosing approach... 2.
Terminal half life is between 5-14 hours, with an average half life of ~9 hours (contrast this, dear readers, with a
Bicalutamide
half life of 5.9 days)... this would seem to indicate 2x per day rather than the 1x per day dosing approach... 2.
SeosamhM
in
Advanced Prostate Cancer
5 years ago
Psa after adt
Psa level after 6months of orchiectomy nd
bicalutamide
came to b 0.07 ng/dl..Bone scan showing increased tracer uptake in left ileum nd acetabulum nd both pubis
Psa level after 6months of orchiectomy nd
bicalutamide
came to b 0.07 ng/dl..Bone scan showing increased tracer uptake in left ileum nd acetabulum nd both pubis
Rafithussain
in
Advanced Prostate Cancer
5 years ago
Conflicts between HIV and PCa meds
My doctor is considering augmenting that with
bicalutamide
to reduce PSA levels as I await radiation therapy (TE is already <0.1 but PSA appears to be not fully responsive).
My doctor is considering augmenting that with
bicalutamide
to reduce PSA levels as I await radiation therapy (TE is already <0.1 but PSA appears to be not fully responsive).
Moxiecat
in
Advanced Prostate Cancer
5 years ago
Has anybody tried Zytiga re challenge after failed chemo?
Aged 54 at diagnosis with no family history of Pca
Bicalutamide
and Prostap then started on Zytiga and prednisalone (March 2015) which stopped March 2018 as PSA rising. Tested at Royal Marsden for BRCA Gene for Olaparib trial but negative so not eligible.
Aged 54 at diagnosis with no family history of Pca
Bicalutamide
and Prostap then started on Zytiga and prednisalone (March 2015) which stopped March 2018 as PSA rising. Tested at Royal Marsden for BRCA Gene for Olaparib trial but negative so not eligible.
Amandaking
in
Advanced Prostate Cancer
5 years ago
Early use of LU-177?
Diagnosed metastatic and placed on
Bicalutamide
150mg psa 1.1 -Nov. 2015. Dec. 2015 -8 rounds of chemotherapy. Post chemo April 2016 psa <0.09. Adding Metformin 1000mg and Statin 40mg to the
Bicalutamide
treatment. Psa 0.5 -june 2018.
Bicalutamide
dosages raised to 300mg.
Diagnosed metastatic and placed on
Bicalutamide
150mg psa 1.1 -Nov. 2015. Dec. 2015 -8 rounds of chemotherapy. Post chemo April 2016 psa <0.09. Adding Metformin 1000mg and Statin 40mg to the
Bicalutamide
treatment. Psa 0.5 -june 2018.
Bicalutamide
dosages raised to 300mg.
MiRob
in
Prostate Cancer Network
5 years ago
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