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Multi-Drug Combo May Be Best Against Prostate Cancer...I thought it was a known fact already!
"Combining two or three testosterone-blocking drugs prevents the spread of prostate cancer better than just a single medication, a new clinical trial has found." Dr Aggrawal again! https://www.usnews.com/news/health-news/articles/2024-01-25/multi-drug-combo-may-be-best-against-prostate-cancer
"Combining two or three testosterone-blocking drugs prevents the spread of prostate cancer better than just a single medication, a new clinical trial has found." Dr Aggrawal again! https://www.usnews.com/news/health-news/articles/2024-01-25/multi-drug-combo-may-be-best-against-prostate-cancer
Maxone73
in
Advanced Prostate Cancer
6 months ago
The saga of faints and Afib
Many thanks to all those who gave advice. Yesterdays 'attack' of faints and afib was pretty dire. So I called 111 and the clinician I spoke to advised I go,by appointmnet...yes, that is what I said, to A. and E. Mine is the John Radcliffe Oxford. I was recieved and put immediately into an area where
Many thanks to all those who gave advice. Yesterdays 'attack' of faints and afib was pretty dire. So I called 111 and the clinician I spoke to advised I go,by appointmnet...yes, that is what I said, to A. and E. Mine is the John Radcliffe Oxford. I was recieved and put immediately into an area where
10gingercats
in
AF Association
11 months ago
Glaucoma, OCT showing deterioration since starting Pred for PMR
I am on 17mgs Pred for PMR for 6 weeks. I have had glaucoma for 8yrs . At my opthalmology FU today the, OCT showed marked deterioration in one eye since March. The GCC Analysis has gone all red, when it was mildly yellow before. Has anyone else noted the same when they went on steroids? I am off for
I am on 17mgs Pred for PMR for 6 weeks. I have had glaucoma for 8yrs . At my opthalmology FU today the, OCT showed marked deterioration in one eye since March. The GCC Analysis has gone all red, when it was mildly yellow before. Has anyone else noted the same when they went on steroids? I am off for
Sillydogsmum
in
PMRGCAuk
11 months ago
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Does it indicate failure of another clinical trial
Annovis blames ‘data cleaning’ efforts for delaying phase 3 Parkinson’s readout https://www.fiercebiotech.com/biotech/annovis-blames-data-cleaning-efforts-delaying-phase-3-parkinsons-readout
Annovis blames ‘data cleaning’ efforts for delaying phase 3 Parkinson’s readout https://www.fiercebiotech.com/biotech/annovis-blames-data-cleaning-efforts-delaying-phase-3-parkinsons-readout
Farooqji
in
Cure Parkinson's
6 months ago
Clinical Trials
Has anyone participated in ANY Clinical Trials?? Which ones and have they helped at all???
Has anyone participated in ANY Clinical Trials?? Which ones and have they helped at all???
smv123
in
Cure Parkinson's
6 months ago
Vitamin D and Dementia
Vitamin D is a topic that gets a regular airing on this forum. In the context of CLL, here is a good place to review past posts https://healthunlocked.com/cllsupport/posts/149126536/recent-research-report?responses=149129259 (reply by Lankisterguy). Personally, the idea of dying with CLL just doesn't
Vitamin D is a topic that gets a regular airing on this forum. In the context of CLL, here is a good place to review past posts https://healthunlocked.com/cllsupport/posts/149126536/recent-research-report?responses=149129259 (reply by Lankisterguy). Personally, the idea of dying with CLL just doesn't
bennevisplace
in
CLL Support
6 months ago
Nuclear Stress Test in Chair was so easy.
Had the Nuclear Stress test in the apparatus similar to a dentist chair. It was a Lexi Scan with injection but did not have to lay flat and was less than half the time of the round donut looking machine. My cardiologist did not have the newer technology he wrote me a referral to go to a cardiologist
Had the Nuclear Stress test in the apparatus similar to a dentist chair. It was a Lexi Scan with injection but did not have to lay flat and was less than half the time of the round donut looking machine. My cardiologist did not have the newer technology he wrote me a referral to go to a cardiologist
Strawberryfields1
in
AF Association
11 months ago
Easy-to-use inhaled levodopa system readying request for US approval
That’s according to results from a company-sponsored clinical trial (NCT06037590) comparing the pharmacological properties of Levodopa Cyclops against those of Inbrija, an approved inhaled powder formulation of levodopa developed by Acorda Therapeutics. “This randomized cross-over trial of Levodopa
That’s according to results from a company-sponsored clinical trial (NCT06037590) comparing the pharmacological properties of Levodopa Cyclops against those of Inbrija, an approved inhaled powder formulation of levodopa developed by Acorda Therapeutics. “This randomized cross-over trial of Levodopa
Farooqji
in
Cure Parkinson's
6 months ago
clinical trial: ATR inhibitor for ATM mutated solid tumors
in vivo and in vitro studies suggest that ATR inhibitors work better than PARP inhibitors for people with ATM gene mutations…but together they may work even better I hope to find more data about this clinical trial https://www.biospace.com/article/releases/aprea-therapeutics-announces-dosing-of-first-patient-in-phase
in vivo and in vitro studies suggest that ATR inhibitors work better than PARP inhibitors for people with ATM gene mutations…but together they may work even better I hope to find more data about this clinical trial https://www.biospace.com/article/releases/aprea-therapeutics-announces-dosing-of-first-patient-in-phase
Maxone73
in
Advanced Prostate Cancer
6 months ago
Arrhythmia anxieties pre-cardioversion
Hi everyone, just looking for others' experiences and reassurance. Since having open heart surgery 12 weeks ago to correct a hole in my heart (diagnosed out of the blue at Christmas), I have been in arrhythmia for about 6 weeks. I had 48 hours on a holter monitor and this showed atrial flutter. I was
Hi everyone, just looking for others' experiences and reassurance. Since having open heart surgery 12 weeks ago to correct a hole in my heart (diagnosed out of the blue at Christmas), I have been in arrhythmia for about 6 weeks. I had 48 hours on a holter monitor and this showed atrial flutter. I was
LadyZ13
in
AF Association
11 months ago
New Thyroid Results - Conversion Issue?
Hi, After an emotional Thyroid rollercoaster these past couple years (post partial thyroidectomy 12/2/21 in combination with an Endo who doesn't believe in compounded medication), I finally seem to be settling into a medication and dose that works okay. I'd have to say that I'm still a bit tired and
Hi, After an emotional Thyroid rollercoaster these past couple years (post partial thyroidectomy 12/2/21 in combination with an Endo who doesn't believe in compounded medication), I finally seem to be settling into a medication and dose that works okay. I'd have to say that I'm still a bit tired and
KarmaMaya
in
Thyroid UK
6 months ago
Current SUPERNOVA Clinical Trial for Reformulated EVUSHELD for preventing COVID-19 infection for immune-impaired individuals
A Phase II sub-study of SUPERNOVA clinical trial (2023) is currently operating to test the efficacy and safety of AZD3152 as a component of a reformulated version of EVUSHELD mAbs prophylaxis for immune-impaired individuals who cannot mount antibody responses to COVID-19 vaccines. Study Understanding
A Phase II sub-study of SUPERNOVA clinical trial (2023) is currently operating to test the efficacy and safety of AZD3152 as a component of a reformulated version of EVUSHELD mAbs prophylaxis for immune-impaired individuals who cannot mount antibody responses to COVID-19 vaccines. Study Understanding
Classicaljazz
in
CLL Support
6 months ago
need some guidance, feeling desperate..
My husband has advanced, Stage IV castration resistant prostate cancer. When he was diagnosed in May 2022 his PSA was 4700, he has widespread bone metastases. He stopped responding to Docetaxel, Pluvicto and is now not responding to Cabazitaxel, his PSA is now over 700. He is feeling good, no pain
My husband has advanced, Stage IV castration resistant prostate cancer. When he was diagnosed in May 2022 his PSA was 4700, he has widespread bone metastases. He stopped responding to Docetaxel, Pluvicto and is now not responding to Cabazitaxel, his PSA is now over 700. He is feeling good, no pain
Kiki27
in
Advanced Prostate Cancer
6 months ago
Taste Issues and finger neuropathy on Xtandi( enzalutamide) ?
In order to participate in a clinical trial (FOR46 at UCSF) I had to switch from Nubeqa (darolutamide) to enzalutamide. Previously on abiraterone. Did really well on both medications. Now 4 months on enzalutamide and my 5th research infusion, I'm experiencing some side effects. Trying to determine
In order to participate in a clinical trial (FOR46 at UCSF) I had to switch from Nubeqa (darolutamide) to enzalutamide. Previously on abiraterone. Did really well on both medications. Now 4 months on enzalutamide and my 5th research infusion, I'm experiencing some side effects. Trying to determine
bandgeek
in
Advanced Prostate Cancer
6 months ago
Can Anyone On This Forum Please Explain
I just got back a little ago from a few hours visit at my local VA Hospital. While I was there I went into AFIB and had an ekg done. The Dr. came in and said my heart rate was high but it's coming down. I told her I know because I have paroxysmal AFIB and she said you have Chronic AFIB. I told her I
I just got back a little ago from a few hours visit at my local VA Hospital. While I was there I went into AFIB and had an ekg done. The Dr. came in and said my heart rate was high but it's coming down. I told her I know because I have paroxysmal AFIB and she said you have Chronic AFIB. I told her I
kocoach
in
Atrial Fibrillation Support
11 months ago
Treating PVCS on a virtual ward
I have posted on here a number of times about the burden of persistent PVCs. Anyway, after 5 days of feeling very dizzy and nauseous, I went to see my GP. She sent me straight to my local hospital which is a big teaching hospital. I was seen in the Same Day Emergency Medicine unit who were thorough and
I have posted on here a number of times about the burden of persistent PVCs. Anyway, after 5 days of feeling very dizzy and nauseous, I went to see my GP. She sent me straight to my local hospital which is a big teaching hospital. I was seen in the Same Day Emergency Medicine unit who were thorough and
Norfolk_spaniel
in
AF Association
11 months ago
Randomised clinical trial - prophylactic radiation therapy to asymptomatic bone metastases improved survival
Prophylactic Radiation Therapy Versus Standard of Care for Patients With High-Risk Asymptomatic Bone Metastases: A Multicenter, Randomized Phase II Clinical Trial Authors: Erin F. Gillespie, MD, MPH https://orcid.org/0000-0002-1386-1542 gillespe@mskcc.org, Joanna C. Yang, MD, MPH, Noah J. Mathis, BA
Prophylactic Radiation Therapy Versus Standard of Care for Patients With High-Risk Asymptomatic Bone Metastases: A Multicenter, Randomized Phase II Clinical Trial Authors: Erin F. Gillespie, MD, MPH https://orcid.org/0000-0002-1386-1542 gillespe@mskcc.org, Joanna C. Yang, MD, MPH, Noah J. Mathis, BA
Graham49
in
Advanced Prostate Cancer
6 months ago
U.S. Gov't to Negotiate Prices for Ibrutinib
https://www.cnn.com/2023/08/29/politics/medicare-drug-price-negotiations/index.html#:~:text=Medicare%20will%20soon%20start%20negotiating%20the%20prices%20of%2010%20drugs%20with%20manufacturers.&text=The%20Biden%20administration%20unveiled%20Tuesday,blood%20thinners%20and%20diabetes%20medications.
https://www.cnn.com/2023/08/29/politics/medicare-drug-price-negotiations/index.html#:~:text=Medicare%20will%20soon%20start%20negotiating%20the%20prices%20of%2010%20drugs%20with%20manufacturers.&text=The%20Biden%20administration%20unveiled%20Tuesday,blood%20thinners%20and%20diabetes%20medications.
michaeledward
in
CLL Support
11 months ago
Surgical Castration ?
I have been on Eligard for two months. Prior to starting ADT my Triglycerides were 100 (May 2023). After only two months of Eligard they are thru the roof (495). Since I have metastatic PC they tell me that I will be on ADT for life. I am considering surgical orchiectomy since there are fewer metabolic
I have been on Eligard for two months. Prior to starting ADT my Triglycerides were 100 (May 2023). After only two months of Eligard they are thru the roof (495). Since I have metastatic PC they tell me that I will be on ADT for life. I am considering surgical orchiectomy since there are fewer metabolic
Bigmaristuff
in
Advanced Prostate Cancer
11 months ago
Heart rates in Afib and NSR
When I was on Sotalol for paroxysmal Afib my heart rate was typically in the range 70 to 125 when in Afib and 60 to 75 in NSR, as measured on my Kardia. For the last month I have been on Flecainide and Verapamil. There now seems to little difference between Afib and NSR heart rates both being in the
When I was on Sotalol for paroxysmal Afib my heart rate was typically in the range 70 to 125 when in Afib and 60 to 75 in NSR, as measured on my Kardia. For the last month I have been on Flecainide and Verapamil. There now seems to little difference between Afib and NSR heart rates both being in the
golfwatcher
in
AF Association
11 months ago
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