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Abiraterone, Prednisone, Apalutamide combo Improves Prostate Cancer Outcomes, Leaves HRQoL Unaffected
Oncological outcomes improved with the addition of abiraterone acetate (Zytiga) plus prednisone (AAP) and apalutamide (Erleada) after radical prostatectomy and did not significantly affect health-related quality of life. https://www.targetedonc.com/view/abiraterone-prednisone-apalutamide-improves-prostate-cancer-outcomes-leaves-hrqol-unaffected
Oncological outcomes improved with the addition of abiraterone acetate (Zytiga) plus prednisone (AAP) and apalutamide (Erleada) after radical prostatectomy and did not significantly affect health-related quality of life. https://www.targetedonc.com/view/abiraterone-prednisone-apalutamide-improves-prostate-cancer-outcomes-leaves-hrqol-unaffected
Maxone73
in
Advanced Prostate Cancer
5 months ago
Nerves taken
I need some understanding. A friend just shared that he had a G8 and a psa of 10.2. He had a RALP and the doc said the cancer was contained to the prostate. Then he said that the doc took both nerve bundles (R & L). How is the cancer contained but required both nerve bundles to be taken?
I need some understanding. A friend just shared that he had a G8 and a psa of 10.2. He had a RALP and the doc said the cancer was contained to the prostate. Then he said that the doc took both nerve bundles (R & L). How is the cancer contained but required both nerve bundles to be taken?
Cyclingrealtor
in
Advanced Prostate Cancer
5 months ago
What is my best treatment option?
Details in bio. Summary - Diagnosed June 2021 PSA 331, mets to spine Started Lupron and Abiraterone [u]Stopped treatment June 2023[/u] Since stopping treatment in June 2023, my [u]PSA has risen[/u] along with my testosterone.
PSA 11/2023 1.3
PSA 12/2023
Details in bio. Summary - Diagnosed June 2021 PSA 331, mets to spine Started Lupron and Abiraterone [u]Stopped treatment June 2023[/u] Since stopping treatment in June 2023, my [u]PSA has risen[/u] along with my testosterone.
PSA 11/2023 1.3
PSA 12/2023
davidw777
in
Advanced Prostate Cancer
5 months ago
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2 or 3 yrs ADT
I was diagnosed im Jan 2022 with Gleason 9. PSA was 5.68. Prostatectomy in April 2022. The post surgical pathology showed 1 of 9 lymph nodes was positive, positive margins and one seminal vesical positive. Started Eligard in June 22 and abiraterone with predisone in July 2022. Radiation (34 days, 68
I was diagnosed im Jan 2022 with Gleason 9. PSA was 5.68. Prostatectomy in April 2022. The post surgical pathology showed 1 of 9 lymph nodes was positive, positive margins and one seminal vesical positive. Started Eligard in June 22 and abiraterone with predisone in July 2022. Radiation (34 days, 68
snugrose
in
Advanced Prostate Cancer
5 months ago
Blood in stool..
Sorry for the Poo talk but here goes.. About a week and a half ago, i was wiping and noticed pink on the paper. When i was done i got the flashlight on and saw a red blood streak along the turd. On the outside of it. It went away so i thought it’s a one-off. then the last couple days three more
Sorry for the Poo talk but here goes.. About a week and a half ago, i was wiping and noticed pink on the paper. When i was done i got the flashlight on and saw a red blood streak along the turd. On the outside of it. It went away so i thought it’s a one-off. then the last couple days three more
groundhogy
in
Advanced Prostate Cancer
5 months ago
Firmagon vs Lupron
So, the question is what are the up or downs if switching from Firmagon to Lupron. I used Orgovyx until it didn't work, switched to Firmagon. Wanted either due to family history with heart issues. Dad, uncle's, brothers, all having issues. One brother recently having a major HA... But the convenience
So, the question is what are the up or downs if switching from Firmagon to Lupron. I used Orgovyx until it didn't work, switched to Firmagon. Wanted either due to family history with heart issues. Dad, uncle's, brothers, all having issues. One brother recently having a major HA... But the convenience
Cooolone
in
Advanced Prostate Cancer
5 months ago
Some good advancements today too: Advances in Engineered Macrophages - A New Frontier in Cancer Immunotherapy
"These cells act synergistically in tumour progression, invasion, metastasis, and response to immunotherapies. Consequently, cancer treatment has transitioned from a model centred solely on the cancer itself to one focused on the
tumour microenvironment
, and cancer immunotherapy has consequently
"These cells act synergistically in tumour progression, invasion, metastasis, and response to immunotherapies. Consequently, cancer treatment has transitioned from a model centred solely on the cancer itself to one focused on the
tumour microenvironment
, and cancer immunotherapy has consequently
Maxone73
in
Advanced Prostate Cancer
3 months ago
Radiotherapy for lung cancer
After an oncologist appointment I was left deflated. I did know the risk of extra damage to the lung and possibly needing oxygen. She was talking like she didn't want me to try. At the moment they said I have 18 months to 2 years left and the Radiotherapy would give me an extra year . All of this is
After an oncologist appointment I was left deflated. I did know the risk of extra damage to the lung and possibly needing oxygen. She was talking like she didn't want me to try. At the moment they said I have 18 months to 2 years left and the Radiotherapy would give me an extra year . All of this is
Lizzielock
in
The Roy Castle Lung Cancer Foundation
5 months ago
Improved Posts and Replies
Responding to ChatGPT charging $20 per month to use the advanced versions of Cancer Copilot and Clinical Trial Navigator: We found a way where you won't have to pay. Starting this month, "Advanced Prostate Cancer" will be power-charged by our AI engine…for free. We know many people have been shy about
Responding to ChatGPT charging $20 per month to use the advanced versions of Cancer Copilot and Clinical Trial Navigator: We found a way where you won't have to pay. Starting this month, "Advanced Prostate Cancer" will be power-charged by our AI engine…for free. We know many people have been shy about
Darryl
Partner
in
Advanced Prostate Cancer
3 months ago
PSMA and bladder Cancer?
I have been having various difficulties with urination and know that my bladder is messed up. I have radiation cystitis and who knows what else. I saw my urologist recently and he had little to offer, sort of said yes you are a mess and pretty much left it at that. I have had PSMA pet scans and SPECT
I have been having various difficulties with urination and know that my bladder is messed up. I have radiation cystitis and who knows what else. I saw my urologist recently and he had little to offer, sort of said yes you are a mess and pretty much left it at that. I have had PSMA pet scans and SPECT
spencoid2
in
Advanced Prostate Cancer
3 months ago
ASCO GU 2024 abstracts
This is the abstract for advanced prostate cancer: https://s3.amazonaws.com/files.oncologymeetings.org/prod/s3fs-public/2024-01/GU24-Prostate-Cancer-Advanced.pdf I suggest to use the search function in your browser, it's 235 pages of abstracts...
This is the abstract for advanced prostate cancer: https://s3.amazonaws.com/files.oncologymeetings.org/prod/s3fs-public/2024-01/GU24-Prostate-Cancer-Advanced.pdf I suggest to use the search function in your browser, it's 235 pages of abstracts...
Maxone73
in
Advanced Prostate Cancer
5 months ago
Rising PSA
Going into 7 years. No prostate. ADT on and off. Recently while on Lupron & NUBEQA PSA continues to rise. Now at 10.1 and Testosterone nondectable. PSMA/PET/CT scan last weeks states no metastases present. We meet with Dr. Aggarwal next week. Last month at our visit he told us at this point “Scans
Going into 7 years. No prostate. ADT on and off. Recently while on Lupron & NUBEQA PSA continues to rise. Now at 10.1 and Testosterone nondectable. PSMA/PET/CT scan last weeks states no metastases present. We meet with Dr. Aggarwal next week. Last month at our visit he told us at this point “Scans
JolleySprings
in
Advanced Prostate Cancer
5 months ago
Mum getting biopsy results tomorrow
Hi all, my beautiful mum is getting her biopsy results tomorrow (Friday) but has been told she has a tumour and there is potential spread to lymph nodes and that the plan will be chemotherapy and immunotherapy. She has had two x rays, a chest CT and bronchoscope/biopsies but no further tests just yet
Hi all, my beautiful mum is getting her biopsy results tomorrow (Friday) but has been told she has a tumour and there is potential spread to lymph nodes and that the plan will be chemotherapy and immunotherapy. She has had two x rays, a chest CT and bronchoscope/biopsies but no further tests just yet
DaughterofDiane
in
The Roy Castle Lung Cancer Foundation
5 months ago
Dental Issues on Finesteride
Five weeks after starting on finesteride 5 mg I developed painfully sensitive teeth both top and bottom on left side of my mouth. Here's what a google search turned up: https://forum.propeciahelp.com/t/propecia-and-dental-problems/1254 https://www.ehealthme.com/ds/finasteride/toothaches/ I became
Five weeks after starting on finesteride 5 mg I developed painfully sensitive teeth both top and bottom on left side of my mouth. Here's what a google search turned up: https://forum.propeciahelp.com/t/propecia-and-dental-problems/1254 https://www.ehealthme.com/ds/finasteride/toothaches/ I became
fast_eddie
in
Fight Prostate Cancer
5 months ago
IMRT WITHOUT THE JELL
I'm scheduled for IMRT Radistion without the jell. Doc says the jell may push cancer microscopic cells away from the prostate. He said the cancer is about to protrude through the capsule and microsopic cancer cells could be out of the capsule and did not want to take a chance of putting the jell in and
I'm scheduled for IMRT Radistion without the jell. Doc says the jell may push cancer microscopic cells away from the prostate. He said the cancer is about to protrude through the capsule and microsopic cancer cells could be out of the capsule and did not want to take a chance of putting the jell in and
woppaginny
in
Advanced Prostate Cancer
3 months ago
Rising PSA -
Diagnosed: May 2021 age 53 otherwise no health issues. Only symptom was increased urination that progressed to painful urination and inability to fully empty bladder. Highest PSA was 5. MRI showed Mets to pelvic lymph, seminal vessels, and pelvic bone. Gleason 4+3 (80% of samples) 4+5 for 10%. CT
Diagnosed: May 2021 age 53 otherwise no health issues. Only symptom was increased urination that progressed to painful urination and inability to fully empty bladder. Highest PSA was 5. MRI showed Mets to pelvic lymph, seminal vessels, and pelvic bone. Gleason 4+3 (80% of samples) 4+5 for 10%. CT
MPCSUX
in
Advanced Prostate Cancer
5 months ago
Radium 223 offered
Hi everyone Husband diagnosed nearly 51/2 years ago. Stage 4 with mets to spine and hip (4 in total) none to organs etc. Had Chemo five years ago ,Zytiga +Pred for 2 1/2 years (now failing ) as PSA is up to 37. We are in UK as some of you know, and Clint has been offered Radium 223 for his bone mets
Hi everyone Husband diagnosed nearly 51/2 years ago. Stage 4 with mets to spine and hip (4 in total) none to organs etc. Had Chemo five years ago ,Zytiga +Pred for 2 1/2 years (now failing ) as PSA is up to 37. We are in UK as some of you know, and Clint has been offered Radium 223 for his bone mets
16starsky
in
Advanced Prostate Cancer
5 months ago
A proposed metabolic treatment for prostate cancer, (theoretical only) using drugs approved for other conditions
See the PaSTe regimen below: pantoprozole (a drug currently used to reduce stomach acid), simvastatin (a statin used to reduce cholesterol), trimetazidine (a drug used to treat angina attacks). PaSTe. Blockade of the Lipid Phenotype of Prostate Cancer as Metabolic Therapy: A Theoretical Proposal
See the PaSTe regimen below: pantoprozole (a drug currently used to reduce stomach acid), simvastatin (a statin used to reduce cholesterol), trimetazidine (a drug used to treat angina attacks). PaSTe. Blockade of the Lipid Phenotype of Prostate Cancer as Metabolic Therapy: A Theoretical Proposal
Graham49
in
Advanced Prostate Cancer
5 months ago
Firmagon seems to have stopped suppressing testosterone
Hi everyone I have been taking firmagon adt treatment for 6 years for stage 4 cancer last 2 blood tests have one a month showed increase in testosterone 0.76 in December then January test 1.76 this last test also showed a rise in psa has anyone had this problem I'm getting the shot regularly
Hi everyone I have been taking firmagon adt treatment for 6 years for stage 4 cancer last 2 blood tests have one a month showed increase in testosterone 0.76 in December then January test 1.76 this last test also showed a rise in psa has anyone had this problem I'm getting the shot regularly
johnscats
in
Advanced Prostate Cancer
5 months ago
PSA Gone Up
I had RP in January of 2023, started ADT in May of 2023 and went through 38 session of SRT between July and August. In am currently on my second six month dose of Eligard and it should be done in May of this year. In November 2023, I had my first PSA test since SRT and it was .008 ng/mL. I just got
I had RP in January of 2023, started ADT in May of 2023 and went through 38 session of SRT between July and August. In am currently on my second six month dose of Eligard and it should be done in May of this year. In November 2023, I had my first PSA test since SRT and it was .008 ng/mL. I just got
toyman79912
in
Advanced Prostate Cancer
5 months ago
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