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Androgen deprivation therapy (ADT)
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Amar Kishan, MD, on Optimal Sequencing of ADT With RT in Nonmetastatic Prostate Cancer
The patients were treated with RT and short-term neoadjuvant/concurrent
ADT
(n=6,325) or concurrent/adjuvant
ADT
(n=1,084), and outcomes were examined by RT field size.
The patients were treated with RT and short-term neoadjuvant/concurrent
ADT
(n=6,325) or concurrent/adjuvant
ADT
(n=1,084), and outcomes were examined by RT field size.
Yearofthecow
in
Prostate Cancer Network
1 year ago
Treatment: Unfavorable Intermediate Risk PCA
I could wait a month for the results of a Decipher test to determine whether
ADT
is needed but the Doctor is 80% confident it will indicate higher risk disease and the need for
ADT
. Therefore, I am leaning toward starting the
ADT
soon rather than waiting for the Decipher report to begin.
I could wait a month for the results of a Decipher test to determine whether
ADT
is needed but the Doctor is 80% confident it will indicate higher risk disease and the need for
ADT
. Therefore, I am leaning toward starting the
ADT
soon rather than waiting for the Decipher report to begin.
rosenjpj
in
Prostate Cancer Network
1 year ago
Why do we stop treatment
This is what I experienced and at the time I made the decision to stop the
ADT
, I was not informed. Like I said I had no idea what I was up against. I was more concerned with the side effects than I was with the disease.
This is what I experienced and at the time I made the decision to stop the
ADT
, I was not informed. Like I said I had no idea what I was up against. I was more concerned with the side effects than I was with the disease.
Islandboy2021
in
Advanced Prostate Cancer
1 year ago
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EMBARK trial
Watching the results of the EMBARK trial with great interest as they had a ‘Lutamide monotheraoy’ arm that has performed very well and now questions are being asked about needing
ADT
for high risk of BCR in the hormone sensitive.
Watching the results of the EMBARK trial with great interest as they had a ‘Lutamide monotheraoy’ arm that has performed very well and now questions are being asked about needing
ADT
for high risk of BCR in the hormone sensitive.
Brysonal
in
Fight Prostate Cancer
1 year ago
Orchidectomy?
And there are still many of the same SE’s that are experienced with
ADT
. Aside from avoiding the injections are there other advantages of getting one? Are there certain situations that make an orchidectomy a preferable treatment choice?
And there are still many of the same SE’s that are experienced with
ADT
. Aside from avoiding the injections are there other advantages of getting one? Are there certain situations that make an orchidectomy a preferable treatment choice?
fireandice123
in
Advanced Prostate Cancer
1 year ago
Goserelin - side effects profile variability between implants
So I am aware that the side effects of
ADT
are both real and yet also exacerbated or lessened by my mood, which of course is also subject to the impact of having high risk PCa and it’s possible long term impact but also the physiological impact of the medication’s removal of most of my testosterone.
So I am aware that the side effects of
ADT
are both real and yet also exacerbated or lessened by my mood, which of course is also subject to the impact of having high risk PCa and it’s possible long term impact but also the physiological impact of the medication’s removal of most of my testosterone.
SimMartin
in
Advanced Prostate Cancer
10 months ago
Clear PSMA scan.?
I started your journey in2018 with a G 3+4 and PSA of 28 ..I went on
ADT
and had Cyberknife SBRT treatment on my prostate and a suspect rib spot after a PSMA scan , All was good until my psa started to rise when I came off
ADT
..My PSA went from 0.06 to 1.2 over a year .
I started your journey in2018 with a G 3+4 and PSA of 28 ..I went on
ADT
and had Cyberknife SBRT treatment on my prostate and a suspect rib spot after a PSMA scan , All was good until my psa started to rise when I came off
ADT
..My PSA went from 0.06 to 1.2 over a year .
Walliam
in
Advanced Prostate Cancer
1 year ago
thoughts on virtual second opinions
His current MO has him on a zoladex injection and next
ADT
has yet to be added. I was looking into getting a second opinion at MD Anderson, Mayo and Sloan Kettering. I noticed that all offered virtual second opinions.
His current MO has him on a zoladex injection and next
ADT
has yet to be added. I was looking into getting a second opinion at MD Anderson, Mayo and Sloan Kettering. I noticed that all offered virtual second opinions.
Jdhanoa
in
Advanced Prostate Cancer
1 year ago
It's Back - The Way Ahead
Going in thought was six months
ADT
and SBRT. He doesn't think six months of
ADT
combined with SBRT to the one pelvic lymph node will get the outcome we're seeking. Says data is more for localized PCa in prostate being radiated.
Going in thought was six months
ADT
and SBRT. He doesn't think six months of
ADT
combined with SBRT to the one pelvic lymph node will get the outcome we're seeking. Says data is more for localized PCa in prostate being radiated.
Hawk56
in
Advanced Prostate Cancer
1 year ago
Enzalutamide or Darolutamide
What concerns me is these drugs are used when
ADT
fails, but
ADT
has not yet failed for me. Will taking these dugs early shorten the effectiveness? Guess that question is for the crystal ball :) I thank in advance, anyone who is able to provide me with help in the decision. Xray
What concerns me is these drugs are used when
ADT
fails, but
ADT
has not yet failed for me. Will taking these dugs early shorten the effectiveness? Guess that question is for the crystal ball :) I thank in advance, anyone who is able to provide me with help in the decision. Xray
x-rays1
in
Advanced Prostate Cancer
1 year ago
PSA rising during triplet therapy. What to ask the oncologist?
The treatment has been going for four months and a half since
ADT
(2 months and a half since Zytiga and Docetaxel was added). He started
ADT
on December, Zytiga and Docetaxel two months later. He is at his third chemo dose, fourth tomorrow, and it went from 99.30 to 99.70 after the third dose.
The treatment has been going for four months and a half since
ADT
(2 months and a half since Zytiga and Docetaxel was added). He started
ADT
on December, Zytiga and Docetaxel two months later. He is at his third chemo dose, fourth tomorrow, and it went from 99.30 to 99.70 after the third dose.
Sissel25
in
Advanced Prostate Cancer
1 year ago
Treatment - radiation vs. surgery
At favorable intermediate stage,
ADT
therapy is not recommended. If it was, I would choose surgery in a heartbeat. I think that would be worse than other adverse effects of treatemnt.
At favorable intermediate stage,
ADT
therapy is not recommended. If it was, I would choose surgery in a heartbeat. I think that would be worse than other adverse effects of treatemnt.
TonyTx
in
Prostate Cancer Network
7 months ago
Time for a vacation, but worried about IADT
Decision time is approaching but should I take an
ADT
vacation? Any new data or articles to support decisions on intermittent
ADT
? I'm looking forward to an improved QoL but just worried about giving the beast room to come back.
Decision time is approaching but should I take an
ADT
vacation? Any new data or articles to support decisions on intermittent
ADT
? I'm looking forward to an improved QoL but just worried about giving the beast room to come back.
PGDuan
in
Advanced Prostate Cancer
1 year ago
Recommendations for top prostate cancer oncologists in Vancouver BC
His current MO has him on a zoladex injection and next
ADT
has yet to be added. I want to ensure my Dad has the best health team. He is currently being treated at BC Cancer in the Fraser Valley.
His current MO has him on a zoladex injection and next
ADT
has yet to be added. I want to ensure my Dad has the best health team. He is currently being treated at BC Cancer in the Fraser Valley.
Jdhanoa
in
Advanced Prostate Cancer
1 year ago
Help on what to expect with this 6 month follow up?
He has been on
ADT
for the last year as well. My questions are: 1. What can we expect on this follow up. Will they just set up new scans to see where he stands? 2. What would be considered a success / failure.
He has been on
ADT
for the last year as well. My questions are: 1. What can we expect on this follow up. Will they just set up new scans to see where he stands? 2. What would be considered a success / failure.
FormulaRob
in
Advanced Prostate Cancer
10 months ago
If all treatment has failed do you continue with ADT?
Now that all treatment has failed to stop the beast do you continue
ADT
? Husband has failed out of 6 pluvicto and now 6 Jevtana. No further treatment is planned. Any reason to continue?
Now that all treatment has failed to stop the beast do you continue
ADT
? Husband has failed out of 6 pluvicto and now 6 Jevtana. No further treatment is planned. Any reason to continue?
Cynthgob
in
Advanced Prostate Cancer
1 year ago
Need help/input on Adjuvant vs salvage radiation after prostatectomy & extended lymph node dissection. Also studies/input on # fractions?
History: Husbands care team planned for a “multi-modality” treatment plan (
ADT
+Zytiga, then prostatectomy with ePLND, followed by adjuvant IMRT), for his Gleason 10, locally advanced PC.
History: Husbands care team planned for a “multi-modality” treatment plan (
ADT
+Zytiga, then prostatectomy with ePLND, followed by adjuvant IMRT), for his Gleason 10, locally advanced PC.
StephH72
in
Advanced Prostate Cancer
11 months ago
Effect of low endogenous testosterone
Starting
ADT
and radiation soon. Have had low testosterone (<150 ng/ml) most of my life. Non-existent libido, depression and tired most of the time. Recent studies have shown that aggressive prostate cancer more common in people with low testosterone.
Starting
ADT
and radiation soon. Have had low testosterone (<150 ng/ml) most of my life. Non-existent libido, depression and tired most of the time. Recent studies have shown that aggressive prostate cancer more common in people with low testosterone.
Doodlebun
in
Advanced Prostate Cancer
1 year ago
Testosterone level while on ADT plus Xtandi
Is it normal/typical for T to stay at 30 when on Xtandi +
ADT
? What T level are others who have been on this for some time?
Is it normal/typical for T to stay at 30 when on Xtandi +
ADT
? What T level are others who have been on this for some time?
Benkaymel
in
Advanced Prostate Cancer
1 year ago
No Benefit With Longer Course of ADT in Localized, High-RiskProstate Cancer
https://www.renalandurologynews.com/home/conference-highlights/genitourinary-cancers-symposium/no-benefit-longer-course-
adt
-localized-high-risk-prostate-cancer/
https://www.renalandurologynews.com/home/conference-highlights/genitourinary-cancers-symposium/no-benefit-longer-course-
adt
-localized-high-risk-prostate-cancer/
ADTMan
in
Advanced Prostate Cancer
1 year ago
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