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SMYD3 enzyme involved in metastases
(B) Expression of SMYD3 mRNA from TCGA–Prostate
Adenocarcinoma
in tumor-adjacent normal prostate tissues (n = 52), Gleason score 6 (n = 45), Gleason score 7 (n = 247), Gleason score 8 (n = 64), and Gleason score 9 (n = 136) prostate tumors. (C to E) Expression of SMYD3 mRNA from PCa datasets.
(B) Expression of SMYD3 mRNA from TCGA–Prostate
Adenocarcinoma
in tumor-adjacent normal prostate tissues (n = 52), Gleason score 6 (n = 45), Gleason score 7 (n = 247), Gleason score 8 (n = 64), and Gleason score 9 (n = 136) prostate tumors. (C to E) Expression of SMYD3 mRNA from PCa datasets.
Derf4223
in
Advanced Prostate Cancer
8 months ago
Any coming back from this?
June 2022: Prostatic biopsy confirmed invasive prostatic
adenocarcinoma
. Started on goserelin. PSA: 8.7. August 2022: Considered for enrollment in a clinical trial but found ineligible due to the absence of HRD mutation. September 2022: Started abiraterone. PSA: 12.6.
June 2022: Prostatic biopsy confirmed invasive prostatic
adenocarcinoma
. Started on goserelin. PSA: 8.7. August 2022: Considered for enrollment in a clinical trial but found ineligible due to the absence of HRD mutation. September 2022: Started abiraterone. PSA: 12.6.
Worriedson9
in
Advanced Prostate Cancer
1 year ago
Uro and Surgeon Recommending Focal Cryoablation
Prostate, left mid, needle core biopsy: - Prostatic
adenocarcinoma
, conventional/acinar type, involving two (2) of fragmented cores (see Comment). - Gleason score: 3 + 3 = 6 (Grade Group 1). - Tumor quantitation: Two (2) small foci, 5% of the total specimen. G.
Prostate, left mid, needle core biopsy: - Prostatic
adenocarcinoma
, conventional/acinar type, involving two (2) of fragmented cores (see Comment). - Gleason score: 3 + 3 = 6 (Grade Group 1). - Tumor quantitation: Two (2) small foci, 5% of the total specimen. G.
rlafford
in
Prostate Cancer Network
2 years ago
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Circulating Lipid Profiles Associated With Resistance to Androgen Deprivation Therapy in Localized Prostate Cancer
Explant Cohort Fasting plasma samples were obtained before surgery from patients undergoing RP for prostate
adenocarcinoma
at St Andrews Hospital in Adelaide, Australia.
Explant Cohort Fasting plasma samples were obtained before surgery from patients undergoing RP for prostate
adenocarcinoma
at St Andrews Hospital in Adelaide, Australia.
podsart
in
Advanced Prostate Cancer
8 hours ago
ONCT-534 Earns FDA Fast Track Designation in R/R Metastatic CRPC
Patients 18 years and older with histologically documented metastatic
adenocarcinoma
of the prostate and a history of CRPC are able to enroll on the study.
Patients 18 years and older with histologically documented metastatic
adenocarcinoma
of the prostate and a history of CRPC are able to enroll on the study.
Scout4answers
in
Advanced Prostate Cancer
10 months ago
Exon20 mutation and Mobocertinib
My stage 4
adenocarcinoma
and bony secondaries were stable over the autumn, but recent scan shows new areas of growth in my lung and liver . This feels like my last chance of extending my life enough to see my 8 month old grandson reach his first birthday .
My stage 4
adenocarcinoma
and bony secondaries were stable over the autumn, but recent scan shows new areas of growth in my lung and liver . This feels like my last chance of extending my life enough to see my 8 month old grandson reach his first birthday .
WoolleySunshine
in
The Roy Castle Lung Cancer Foundation
2 years ago
Diagnosed with Adenosquamous lung cancer
I've been diagnosed with T4 N3 M1b Adenosquamous lung cancer ("predominantly
adenocarcinoma
with some squamous features" according to the biopsy) and am due to see the oncologist next week to discuss possible treatments.
I've been diagnosed with T4 N3 M1b Adenosquamous lung cancer ("predominantly
adenocarcinoma
with some squamous features" according to the biopsy) and am due to see the oncologist next week to discuss possible treatments.
beesgood
in
The Roy Castle Lung Cancer Foundation
1 year ago
Bubbles in lung
I've been with stage 4
adenocarcinoma
for 3 years now, and recently have had a worrying new symptom: it feels as if my lungs are clogged up with bubbles. It's like breathing through a straw into treacle.
I've been with stage 4
adenocarcinoma
for 3 years now, and recently have had a worrying new symptom: it feels as if my lungs are clogged up with bubbles. It's like breathing through a straw into treacle.
pt45
in
The Roy Castle Lung Cancer Foundation
1 year ago
BCR Prediction?
5 years post-prostatectomy at age 59: GL 4+3 (80% pattern 4), PSA 2.9, negative margins, perineural invasion identified, negative lymph nodes (8), tumor extent moderate,
adenocarcinoma
.
5 years post-prostatectomy at age 59: GL 4+3 (80% pattern 4), PSA 2.9, negative margins, perineural invasion identified, negative lymph nodes (8), tumor extent moderate,
adenocarcinoma
.
PlateBlocker
in
Prostate Cancer Network
1 year ago
Sadly, I've joined the PCa club ...
NOTE: Although these findings are highly atypical and suspicious for
adenocarcinoma
, there is insufficient cytologic and/or architectural atypia to establish a definitive diagnosis.
NOTE: Although these findings are highly atypical and suspicious for
adenocarcinoma
, there is insufficient cytologic and/or architectural atypia to establish a definitive diagnosis.
nvidia-ati
in
Prostate Cancer Network
1 year ago
Questions, question's ... problems 4 year's after Lobectomy !
I haven't been here for quite a while but I wanted to ask for a bit of advice from those who had
Adenocarcinoma
of the lung and have had a Lobectomy.
I haven't been here for quite a while but I wanted to ask for a bit of advice from those who had
Adenocarcinoma
of the lung and have had a Lobectomy.
Danni54
in
The Roy Castle Lung Cancer Foundation
1 year ago
Alternatives
Testing is still ongoing but so far reports
Adenocarcinoma
of prostate Gleason 3+4 in 6 out of 6 cores up to 70% involvement ,with Gleason 4 about 20% MRA staging T3a NO Oh and just to add to my joys this routine test of the UK's aged revealed 'poorly controlled atrial flutter throughout the
Testing is still ongoing but so far reports
Adenocarcinoma
of prostate Gleason 3+4 in 6 out of 6 cores up to 70% involvement ,with Gleason 4 about 20% MRA staging T3a NO Oh and just to add to my joys this routine test of the UK's aged revealed 'poorly controlled atrial flutter throughout the
Gollam
in
Advanced Prostate Cancer
1 year ago
Just finished my PC radiotherapy sessions, last Wed. My 'diet' an absolute nightmare, after evening meal, toilet duty is top of the list!
I was treated for
adenocarcinoma
grade 7, after biopsy last June, 20 sessions. Told to keep off "fruit and veg" probably two weeks some sorts of normality return 'a bit', but everyone is different?
I was treated for
adenocarcinoma
grade 7, after biopsy last June, 20 sessions. Told to keep off "fruit and veg" probably two weeks some sorts of normality return 'a bit', but everyone is different?
Adlon57
in
Advanced Prostate Cancer
2 years ago
Please Help Explain Results Please help explain Pathology report after Davinci Radical Prostatectomy w/ Extended Lymph Node Dissection
HISTOLOGIC TYPE: Acinar
adenocarcinoma
III. HISTOLOGIC GRADE: Grade Group 4 (Gleason score: 4+4=8) IV.
HISTOLOGIC TYPE: Acinar
adenocarcinoma
III. HISTOLOGIC GRADE: Grade Group 4 (Gleason score: 4+4=8) IV.
Shorehousejam
in
Advanced Prostate Cancer
1 year ago
Ravid Straussman & the Tumor Biome
Gemcitabine is commonly used to treat pancreatic ductal
adenocarcinoma
(PDAC), and we hypothesized that intra-tumor bacteria might contribute to drug resistance of these tumors.
Gemcitabine is commonly used to treat pancreatic ductal
adenocarcinoma
(PDAC), and we hypothesized that intra-tumor bacteria might contribute to drug resistance of these tumors.
pca2004
in
Fight Prostate Cancer
1 year ago
Hi all I’ve not been here for nearly 3 months time has disappeared recently. Last time here was the night before my surgery.
Histology came back as Stage 1c2 mucinous
adenocarcinoma
. Was suspected ( as most mucinous are ) that it was a secondary tumour from GI origin ( stomach / bowel) I’ve had a Gastroscopy and 2 x Colonoscopy since and am now waiting on histology of a massive polyp removed .
Histology came back as Stage 1c2 mucinous
adenocarcinoma
. Was suspected ( as most mucinous are ) that it was a secondary tumour from GI origin ( stomach / bowel) I’ve had a Gastroscopy and 2 x Colonoscopy since and am now waiting on histology of a massive polyp removed .
Deli44
in
My Ovacome
2 years ago
Could the schwannomas on my prostate be mistaken for cancer on various scans?
I have schwannomas on my Prostate gland, [Schwannomatosis NF3], could they be 'diagnosed' as "Prostate Cancer"
Adenocarcinoma
grade 7, I have had irregular urinary flow since the start of the schwannomas in early 2020?
I have schwannomas on my Prostate gland, [Schwannomatosis NF3], could they be 'diagnosed' as "Prostate Cancer"
Adenocarcinoma
grade 7, I have had irregular urinary flow since the start of the schwannomas in early 2020?
Adlon57
in
Advanced Prostate Cancer
2 years ago
PET Scan follow up
Narrative EXAMINATION: PET CT SKULL BASE TO MID THIGH CLINICAL INFORMATION: History of right lower lobectomy and right upper lobe wedge resection with pathology showing invasive
adenocarcinoma
. Monitoring of malignancy following completion of therapy.
Narrative EXAMINATION: PET CT SKULL BASE TO MID THIGH CLINICAL INFORMATION: History of right lower lobectomy and right upper lobe wedge resection with pathology showing invasive
adenocarcinoma
. Monitoring of malignancy following completion of therapy.
kri312
in
Lung Cancer Support
1 year ago
PSA after 4-5 months on Lupron (Scholz)?
I don't trust PSA as a good indicator of my metastatic PCa in the bones, since an actual bone biopsy showed
adenocarcinoma
that was PSMA-Positve and PSA-Negative, but it's still an interesting thought journey.
I don't trust PSA as a good indicator of my metastatic PCa in the bones, since an actual bone biopsy showed
adenocarcinoma
that was PSMA-Positve and PSA-Negative, but it's still an interesting thought journey.
Gl448
in
Advanced Prostate Cancer
1 year ago
BRCA2 and prostate cancer
Other 7 cores, benign Total cores 22; 13 prostatic
adenocarcinoma
Other significant consideration: When he was 30, he fell off of his bike down a 25 ft drop over a bridge and sustained significant pelvic/nerve damage.
Other 7 cores, benign Total cores 22; 13 prostatic
adenocarcinoma
Other significant consideration: When he was 30, he fell off of his bike down a 25 ft drop over a bridge and sustained significant pelvic/nerve damage.
ElaineLynette
in
Prostate Cancer Network
1 year ago
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