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Seeking input on Australia for Lu-177 for my dad
He has failed multiple rounds of chemo, hormone treatments (both
abiraterone
and enzalutamide). With his PSA at over 700 and overwhelming pain and weakness, he recently received his first dose of Lu-177. Fortunately, he seems to be responding well.
He has failed multiple rounds of chemo, hormone treatments (both
abiraterone
and enzalutamide). With his PSA at over 700 and overwhelming pain and weakness, he recently received his first dose of Lu-177. Fortunately, he seems to be responding well.
sandiegosmiles
in
Advanced Prostate Cancer
6 years ago
Statin use and survival in metastatic castration-resistant PCa treated with abiraterone or enzalutamide after docetaxel failure.
"Five hundred and ninety-eight patients treated with second-line
abiraterone
or enzalutamide after docetaxel for mCRPC were included. A total of 199 men (33.3%) received statins during
abiraterone
/enzalutamide treatment.
"Five hundred and ninety-eight patients treated with second-line
abiraterone
or enzalutamide after docetaxel for mCRPC were included. A total of 199 men (33.3%) received statins during
abiraterone
/enzalutamide treatment.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Only early chemo? Or early abiraterone too?
My concern is that he will become castrate resistant before he has the chance to start on
abiraterone
, lessening it’s effectiveness.
My concern is that he will become castrate resistant before he has the chance to start on
abiraterone
, lessening it’s effectiveness.
Jlcwonderboy
in
Advanced Prostate Cancer
6 years ago
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Brittle nails (on Zytiga/abiraterone)
My husband recently started on Zytiga (after being on Xtandi for almost two years). He's noticed that his nails are really brittle, cracking, peeling, ridging. I read about using Aquaphor on them, which we're trying. He did chemo almost three years ago, and only short 5-day bursts of radiation on
My husband recently started on Zytiga (after being on Xtandi for almost two years). He's noticed that his nails are really brittle, cracking, peeling, ridging. I read about using Aquaphor on them, which we're trying. He did chemo almost three years ago, and only short 5-day bursts of radiation on
Caring7
in
Advanced Prostate Cancer
6 years ago
EAU18 - Copenhagen. Hormone-Naive PCa.
Abiraterone
has been demonstrated to be superior to docetaxel in efficacy, acute toxicity, toxic deaths, and convenience. However, the costs of
abiraterone
are significantly higher than that of docetaxel.
Abiraterone
has been demonstrated to be superior to docetaxel in efficacy, acute toxicity, toxic deaths, and convenience. However, the costs of
abiraterone
are significantly higher than that of docetaxel.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
MyFightWithProstateCancer
Therapy with
abiraterone
or apalutamide has been postponed.
Therapy with
abiraterone
or apalutamide has been postponed.
PhilipSZacarias
in
Advanced Prostate Cancer
6 years ago
EAU18 - Copenhagen. Castration Resistant PCa [CRPC]
The available data on
abiraterone
and enzalutamide support maintained efficacy in this setting. [1] Another recently published study assessed the effect the addition of enzalutamide had in MCRPC patients who progressed after 24 weeks with
abiraterone
. [2] The primary endpoint was radiographic progression
The available data on
abiraterone
and enzalutamide support maintained efficacy in this setting. [1] Another recently published study assessed the effect the addition of enzalutamide had in MCRPC patients who progressed after 24 weeks with
abiraterone
. [2] The primary endpoint was radiographic progression
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Statins and Abiraterone
For the last 6+ years I’ve been taking
Abiraterone
/Prednisone and Zoladex with remarkable results, given my dx. I’m now considering adding a statin to help with cholesterol increase, and the earlier post regarding Simvastatin research producing good results has added to the positive side.
For the last 6+ years I’ve been taking
Abiraterone
/Prednisone and Zoladex with remarkable results, given my dx. I’m now considering adding a statin to help with cholesterol increase, and the earlier post regarding Simvastatin research producing good results has added to the positive side.
TommyTV
in
Advanced Prostate Cancer
6 years ago
ASCO Issues New Guidelines for Optimizing Anticancer Therapy in Metastatic non-CRPC.
. - For men with high-risk de novo metastatic non-castrate prostate cancer, the addition of
abiraterone
to ADT should be offered. - For men with lower-risk de novo metastatic non-castrate prostate cancer,
abiraterone
may be offered. - The appropriate regimen of
abiraterone
is 1,000 mg with either prednisolone
. - For men with high-risk de novo metastatic non-castrate prostate cancer, the addition of
abiraterone
to ADT should be offered. - For men with lower-risk de novo metastatic non-castrate prostate cancer,
abiraterone
may be offered. - The appropriate regimen of
abiraterone
is 1,000 mg with either prednisolone
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Testosterone metabolites inhibit proliferation of castration- and therapy-resistant PCa.
Abstract Novel treatments for castration-resistant prostate cancer (CRPC) such as
abiraterone
acetate (AA) or enzalutamide effectively target the androgen pathway to arrest aberrant signalling and cell proliferation. Testosterone is able to inhibit tumour cell growth in CRPC.
Abstract Novel treatments for castration-resistant prostate cancer (CRPC) such as
abiraterone
acetate (AA) or enzalutamide effectively target the androgen pathway to arrest aberrant signalling and cell proliferation. Testosterone is able to inhibit tumour cell growth in CRPC.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
IMAAGEN - Abiraterone Acetate & Prednisone in non-mCRPC.
KEYWORDS:
abiraterone
acetate; prostatic neoplasms PMID: 29630978 DOI: 10.1016/j.juro.2018.03.125 ... [2] https://www.clinicaltrials.gov/ct2/show/NCT01314118?term=IMAAGEN&rank=1
KEYWORDS:
abiraterone
acetate; prostatic neoplasms PMID: 29630978 DOI: 10.1016/j.juro.2018.03.125 ... [2] https://www.clinicaltrials.gov/ct2/show/NCT01314118?term=IMAAGEN&rank=1
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Apalutamide
I have been taking this [u]new[/u] met [i]daily[/i] along with heavy hitter
acetate (Zytega). Also thrown into this [i]daily[/i] mix is
Indomethacin
and
Prednisone
. Lastly, to top this off I've been getting [i]monthly[/i] injections of
Degarelix
.
I have been taking this [u]new[/u] met [i]daily[/i] along with heavy hitter
acetate (Zytega). Also thrown into this [i]daily[/i] mix is
Indomethacin
and
Prednisone
. Lastly, to top this off I've been getting [i]monthly[/i] injections of
Degarelix
.
tkalaf
in
Advanced Prostate Cancer
6 years ago
Taking Prostate Drug Abiraterone (Zytiga) with Food Could Save $300,000
Taking Prostate Drug
Abiraterone
(Zytiga) with Food Could Save $300,000 https://www.peoplespharmacy.com/2018/03/29/taking-prostate-drug-
abiraterone
-zytiga-with-food-could-save-300000/?
Taking Prostate Drug
Abiraterone
(Zytiga) with Food Could Save $300,000 https://www.peoplespharmacy.com/2018/03/29/taking-prostate-drug-
abiraterone
-zytiga-with-food-could-save-300000/?
20PeteG16
in
Advanced Prostate Cancer
6 years ago
It's Half Time at the Chemo Bowl - I am in front right now
MO advises that next treatments are likely to be hormonal -
abiraterone
or enzalutamide I guess. But since I am already hormone-independent I don't know how much this will help. Since I failed ADT within 3 months I asked MO if I have ARV7 splice variant.
MO advises that next treatments are likely to be hormonal -
abiraterone
or enzalutamide I guess. But since I am already hormone-independent I don't know how much this will help. Since I failed ADT within 3 months I asked MO if I have ARV7 splice variant.
Hazard
in
Advanced Prostate Cancer
6 years ago
Phase II Study of Low-Dose Abiraterone With Food.
term=
Abiraterone
+Szmulewitz&rank=1
term=
Abiraterone
+Szmulewitz&rank=1
pjoshea13
in
Advanced Prostate Cancer
6 years ago
[177Lu]-PSMA-617 Has Activity in Castration-Resistant Prostate Cancer
Hofman, Violet, and colleagues evaluated the efficacy and safety of LuPSMA in a prospective phase II trial of 30 patients with metastatic castration-resistant prostate cancer who had progressed after standard therapies including taxane-based chemotherapy and second-generation antiandrogens (
abiraterone
Hofman, Violet, and colleagues evaluated the efficacy and safety of LuPSMA in a prospective phase II trial of 30 patients with metastatic castration-resistant prostate cancer who had progressed after standard therapies including taxane-based chemotherapy and second-generation antiandrogens (
abiraterone
tango65
in
Advanced Prostate Cancer
6 years ago
Yonsa vs Zytiga
20News%205-24-18&utm_content=CURE%20Breaking%20News%205-24-18+CID_2c56c8562f2ebb7c4451afd760438ae8&utm_source=Campaign%20Monitor&utm_term=Read%20full%20story FDA Approves Combination Treatment for Metastatic Prostate Cancer The Food and Drug Administration (FDA) approved a new formulation of Yonsa (
abiraterone
20News%205-24-18&utm_content=CURE%20Breaking%20News%205-24-18+CID_2c56c8562f2ebb7c4451afd760438ae8&utm_source=Campaign%20Monitor&utm_term=Read%20full%20story FDA Approves Combination Treatment for Metastatic Prostate Cancer The Food and Drug Administration (FDA) approved a new formulation of Yonsa (
abiraterone
JLS1
in
Advanced Prostate Cancer
6 years ago
Non Standard of Care Advice!
Went on Lupron and Casodex end of March 2017, and switched to Lupron and
Abiraterone
in August, 2017. My PSA and T have been 0 ever since. Based on advice from this board, i opted (found a very good surgeon) who performed a RP end of January 2017.
Went on Lupron and Casodex end of March 2017, and switched to Lupron and
Abiraterone
in August, 2017. My PSA and T have been 0 ever since. Based on advice from this board, i opted (found a very good surgeon) who performed a RP end of January 2017.
Stickingaround1
in
Advanced Prostate Cancer
6 years ago
Neutrophil-to-Lymphocyte ratio [NLR] & Abiraterone.
KEYWORDS: CRPC; NLR;
abiraterone
acetate PMID: 29541468 PMCID: PMC5838297 DOI: 10.3892/mco.2018.1573
KEYWORDS: CRPC; NLR;
abiraterone
acetate PMID: 29541468 PMCID: PMC5838297 DOI: 10.3892/mco.2018.1573
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Olaparib/Durvalumab Combo Shows Promise in mCRPC
Some 94% had received treatment previously with enzalutamide, 65% with
abiraterone
, and 59% with both agents. Almost half (47%) had prior immunotherapy and 65% had prior chemotherapy. Eighty-two percent had an ECOG performance status of 1.
Some 94% had received treatment previously with enzalutamide, 65% with
abiraterone
, and 59% with both agents. Almost half (47%) had prior immunotherapy and 65% had prior chemotherapy. Eighty-two percent had an ECOG performance status of 1.
JLS1
in
Advanced Prostate Cancer
6 years ago
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