ACUTE ONSET OF BULLOUS SKIN RASH AND A... - Sweet's Syndrome UK

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ACUTE ONSET OF BULLOUS SKIN RASH AND ACUTE KIDNEY INJURY AFTER EXPOSURE TO RADIOCONTRAST

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ACUTE ONSET OF BULLOUS SKIN RASH AND ACUTE KIDNEY INJURY AFTER EXPOSURE TO RADIOCONTRAST: SWEET'S SYNDROME, 2023 (Free PDF).

"This report has described a case of radiocontrast-induced haemorrhagic bullous SS associated with contrast-induced acute kidney injury. History, clinical examination with abrupt onset of a painful erythematous rash, dense neutrophilic dermal infiltrate without vasculitis after drug/contrast exposure, and resolution of symptoms after urgent cessation and early initiation of high-dose steroids all suggested a diagnosis of SS."

- A 67-year-old woman with a medical history of high blood pressure, overactive thyroid, myelodysplastic syndrome (blood cancer), and pyoderma gangrenosum (a neutrophilic dermatosis).

- Sudden onset of skin rash, 24 hours after computed tomography (CT) scans for further evaluation of conditions associated with pyoderma gangrenosum. CT with a radiocontrast agent, e.g. an iodine-based dye injected into a vein, gives a clearer picture of the organs.

- Painful, bloody skin rash had started in her mouth and face and spread to her chest, arms, and legs.

- Worsening heartburn and decreased urine output.

- Diagnosed with radiocontrast-induced bullous Sweet's syndrome (blister-type acute febrile neutrophilic dermatosis triggered by a radiocontrast agent).

- Radiocontrast agent also caused acute kidney injury. ejcrim.com/index.php/EJCRIM...

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