I have Pbc which is a non alcohol related cirrhosis of the liver, this is an auto immune disease. I also have lichen sclerosis, lichen planus, psoriasis and raynauds. The raynauds has got worse since starting methotrexate to help with the lichen sclerosis. I seem to be getting one auto immune disease after the other has anyone else noticed this. I really wonder if the raynauds is just yet another auto immune problem or has been cause/made worse by the methotrexate. Any help.