I wondered if this would be helpful to anyone who suffers Raynauds badly and Scleroderma. I went to see my consultant last week and I have a new doctor. I explained how ill I have been getting. He started me on a new treatment for my Raynauds. Said it is being done at the London Royal Free. It is a NitroDur 0.4mg/hr 10mg/24 hour patch. Well I have already noticed a change how I am feeling. Only down side is I have is the dull headache all day and a severe headache later. I have been timing it. I put it on at 8 am and have only been able to keep it on for about 10 hours. Then the headache from Hell comes, god it is a bad one. Like a severe migraine. You cannot do anything but sit and wait for it to go away. I was advised to remove the patch and put it back on after the headache as gone. Tried that and only managed another couple of hours. Last night I got to 12 hours before the headache. Perhaps you have to build it up. Anyone else using this and can advise me on it. Does it get better the longer you use it headache wise.