Ibrance Remission

[Spettis7]

Has anyone went into full remission from taking ibrance?

[Merma]

I have been in remission from endometrial cancer and on Ibrance/anastrozole for over 5 ½ years. I started this regimen after my second recurrence which was treated with brachytherapy (in my stomach muscle - not fun). I get scanned every 6 months - the next will be next week. Always waiting for the other shoe to drop.

[Spettis7 in reply to Merma]

Thank you , for responding to my question. 5 1/2 years is a blessing!

[Aprilfoolz1]

I have been on Ibrance with fulvestrant for 4 years . I have had clear or no evidence of active disease on Ct/pet scans for 3 plus years. My blood work has always been normal . At stage IV they have never used the word "remission ". Cancer cells are circulating (microscopically right now ) so I'm thankful for every day and try to enjoy living as much as possible , scan to scan .

[Merma in reply to Aprilfoolz1]

My doctor calls it "well-managed cancer."

[Discocat]

I agree with Aprilfoolz....at stage 4 and with extensive bone mets in my case all over the place.....I don't think remission is possible. I've been two years since diagnosis and I'm taking Ibrance, Letrozole, Zoladex and 3 monthly Zometa. My scans show stability and no active disease (NEAD).

[hurricaneheather]

mBC diagnosis in July 2015. started treatment in August 2015; still on first line of treatment. NEAD since 2016. Signatera ctDNA blood results “0.00.”

[Spettis7 in reply to hurricaneheather]

This gives me a lot of hope! Thank you!

[hurricaneheather in reply to Spettis7]

hope! hope opens the door to possibility and requires action for the change one desires.

[Spettis7 in reply to hurricaneheather]

I totally agree with you with hope all things are possible! Stage four remission is possible!!

[kparekh76]

Early stage cancer uses the term 'remission' when cancer is not evidenced within the first five years, and 'cancer-free' when cancer is not evidenced after the first five years.

Late stage cancer (stage IV/metastatic) uses the term 'no evidence of disease' or 'no evidence of active disease' when cancer is not evidenced.

I was diagnosed Stage IV de novo in 2015 and have been on Ibrance since 2019. I have had no evidence of active disease on this drug for years. Hope that helps!

[Spettis7 in reply to kparekh76]

Yes, it does help! Thank you!

[embrace28]

I have also been diagnosed in 2019 de novo. Using Ibrance, letrozole and lupron shot every 3 months. Cleared mets to liver and supraclavicular lypmh nodes! Grateful for each day!

[Mytanya]

I have been in full remission for almost 3 years on Ibrance and anastrazole

[Spettis7 in reply to Mytanya]

Thank you! I am grateful for each day!

[AvidBooklover]

NED since summer of 2019...4+ years on Ibrance. Had one met in hip in Apr 2019. Orig diag in Oct 2012.

[Spettis7 in reply to AvidBooklover]

Thank you for sharing your experience! I have been on ibrance since March 2021 and I changed my diet. I have been in remission since April 2022!

[Tantalon7211 in reply to Spettis7]

Can you tell me what you changed in your diet- I am going back on Ibrance next week-two weeks on and two weeks off - do you have side effects

[Spettis7 in reply to Tantalon7211]

I started intermittent fasting. I eat a lot of kale, broccoli, spinach, tumeric and ginger. I also drink green tea without any sweeteners twice a day. Mediation has been a big help and last but not lease prayer. I also started researching cancer killing foods. The ibrance and letrozole does work but when I changed my diet and mindset that is when my body felt better and my results improved!

[Spettis7 in reply to Tantalon7211]

Side effects have been since the beginning of starting ibrance and letrozole. Arthritis, constipation and hot flashes. These side effects have all improved.

[Shar313]

I was diagnosed stage IV de nova with Mets to the peritoneal Jan 2019. I have been on Ibrance and Letrozole since Feb 2019 and have been NED since Oct 2019.

[Susan1953]

I was diagnosed de novo in 2017 with stage 4, Mets to bones. I have been on Ibrance 125mg and letrozole and zometa infusion every 3 months since April 2017. My scans used to be every 3 months and now are every 6 months. I have been NEAD since November 2017. I don’t think the word “remission” is ever used because the cancer cells are thought to be in your body hiding somewhere.

[Fiercelypink]

I have a friend who had stage 4 breast cancer. She has been on ibrance for 3-4 years now, and her scans have been completely clear for so long that they are considering taking her off of it.

I took ibrance for a year. my scans cleared up and I had radiation and went off it because my recurrence is local. My cancer showed up again on scans about 9 months after I stopped ibrance.

[Spettis7 in reply to Fiercelypink]

I am so sorry to hear about your cancer showing up again! I wish you well!

[Fiercelypink in reply to Spettis7]

Thank you! I'm actually doing well on Kiqali now, and the side effects are much easier for me than they were on Ibrance.

[Gingerann1]

As many here have said, with Stage IV cancer the term remission is misleading. My Onc used the term when my scans showed “no evidence of metastatic disease” 18 months ago. He actually said “deep remission”. Any of us are happy to report and celebrate no evidence of disease (NED) being fully aware that with StageIV, cancer cells are in our bodies hiding, in wait to rear their ugly heads somewhere that will show up on scans. For me, just thinking of this currently terminal disease as a manageable chronic illness gets me through the day and the strength to get up and keep fighting tomorrow. Until there is a systemic cure that can eradicate all cancer cells this is where we’ll be. Thankful to hear so many of you are also NED and praying for a cure for all dealing with this insidious disease.

[genealogy74]

I have been on Ibrance for about 9 months. The term they currently use to describe my situation is "stable." I've never seen the term NED on any of my reports. However, I'll take it. Feel good. I also get monthly fulvestrant shots.

[Gramat]

Yes me. 3.5 year. Pet scan on Wednesday.

[Spettis7 in reply to Gramat]

Hope that all test came back good!

[Gramat]

Had PET scan yesterday and will be getting results tomorrow - nerve wrecking

[Gramat in reply to Gramat]

September Pet San showed no evidence .

I had bloods done today and my Ca15.3 has climbed from 26 to 34.8 (this is highest I have had since treated with radio, Ibrance, Letrozole and Denusomab February 2020. I have to say my levels fluctuate a lot figures before 26 where 18 and before that 28.

I have sinusitis and allergies going on for ten days and yesterday started on 200mg of Doxycycline (had bloods this morning?) could sever viral infection/allergies and antibiotic caused raise?

[Spettis7]

Yes, PET scans are nerve wrecking for me too. I am praying that no cancer is active in your body!

[Granny333]

Hello, I have been off of Ibrance for 6 months now. It brought my blood count down to low. I will find out next week if I need to go back on after scans.

[KimberlyB40]

I was put on Ibrance in March 2021 at 1st stage IV diagnosis. At my 6 month scan I was "no evidence of active disease" and last weeks Petscan still as same thing. I actually just came on this site right now to ask the same question. So September was 2 years since there's been no active cancer.