minimal experience with ibrance

[IzzyZorro]

I don’t have much to share, except that I stopped taking I Brandts when I found Gallium Maltolate. This is not an approved drug, but it is available. It did reduce, and in some cases illuminate all spots of cancer in my body. Good luck in your journey!

[Lynn-in-California]

Do you have glioblastoma or do you have breast cancer? If you have breast cancer, what kind and what stage are you? Are you in a Stage 1 clinical trial? Are you in the United States or are you elsewhere? Are you under the care of a licensed oncologist? In the United States, unless you are in a clinical trial, oncologists must treat you according to approved therapies that show scientific efficacy, are FDA approved, or are an official option under an accepted professional standard of care. I am not aware of this therapy and am concerned that you are promoting something that is not a legit, approved medical treatment. If I am simply uninformed, my apologies.

[Kerryd22]

This isn’t approved for animals let alone humans. go.drugbank.com/drugs/DB05420

[diamags]

They have used it on humans, it doesn't appear ever for breast cancer. ncbi.nlm.nih.gov/pmc/articl...

[Hazelgreen]

I don't understand the thinking behind the above comments!

When I googled, "Gallium Maltolate", Wikipedia gave the following information: "Gallium maltolate is a coordination complex consisting of a trivalent gallium cation coordinated to three maltolate ligands. The compound is a potential therapeutic agent for cancer, infectious disease, and inflammatory disease" (bolding added).

Also, the National Cancer Institute gave the following information for gallium maltolate:

"An orally bioavailable form of the element gallium (Ga) composed of a trivalent gallium cation (Ga3+) coordinated to three maltolate ligands, with anti-inflammatory, anti-proliferative, antineoplastic, analgesic, antiresorptive and antibacterial activities. Upon administration of gallium maltolate, Ga3+, which is structurally similar to the ferric ion (Fe3+), competes with and replaces Fe3+ in many vital Fe 3+-mediated biological reactions.. Unlike Fe3+, Ga3+ cannot be reduced, cannot participate in redox reactions and cannot mimic Fe3+ functions. In rapidly proliferating cells, such as cancer cells, high amounts of iron are needed for DNA synthesis. The incorporation of Ga3+ inactivates the Fe3+-dependent enzyme ribonucleotide reductase (RR), an enzyme essential for DNA synthesis, leading to an inhibition of DNA synthesis and induction of cell death in rapidly proliferating cells. Gallium similarly reduces bacterial cell growth. In addition, Ga3+ is able to suppress inflammation through the down-regulation of pro-inflammatory cells and the inhibition of pro-inflammatory cytokine secretion. Gallium also exerts analgesic effects due to the inhibition of Fe3+-dependent enzymes involved in inflammation and may interfere with the activity of certain metalloproteinases and neuropeptides that are implicated in pain. Also, gallium is able to inhibit bone resorption by osteoclasts, may inhibit metastasis to bone and may prevent the destruction of bone by tumors (bolding added)."

[RLN-overcomer in reply to Hazelgreen]

Thank you Sister/Warrior for this information, that sounds promising I pray, you, and your loved ones will have a Happy,and Healthy2023NewYear😇👍

[mountainwoman1]

Interesting. Thank you for sharing. Numerous articles pop up when I Googled it. It is worth a discussion with your oncologist.

bloodcytology.com/gallium-m...