A couple of months ago I was struggling with the dosage schedule of IBrance 100 mg. I wrote (extensively) about the 5/2 schedule that I hoped would mitigate the Low ANC numbers and poor RBC/WBC counts. I was extremely worried about having to wait two weeks before restarting my cycles.
First thank you to all the ladies who responded, offered suggestions or wondered about the 5/2 schedule.
Well, two months later, I am relieved and happy to say that the new 5 days on and 2 days off schedule is working very, very well. I don’t have the crashing depression and fatigue that I experienced before. I restart my new cycle right on schedule and feel much more “normal” …can play golf and enjoy activities without worrying that I’ll be affected by the dreadful 6+ days of feeling too low to do much of anything.
I did develop acid reflux during the night time hours but again, the ladies came to my rescue and suggested I try taking the IBrance earlier in the day, not after supper. Now I take it in the. I’d afternoon with a cup of tea. The acid reflux is now gone. I’m feeling pretty glad that I have this lovely community of fellow ladies who are interested, can help, and whom I can hope to help in return…I hope!🥰
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Dragonfly2
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i'm really glad that worked out so well for you. This forum is great!
It does make you wonder, though, why the oncologist can't recommend these changes him/herself. You've obviously got a much better quality of life doing it this way!
You might have to convince your oncologist to try this 5/2 even though many people are on it Insist that you try it or get a second opinion. It is more common now. They were just exploring when he refused to try it.
I've been promoting the 5/2 schedule here for years. After a couple of months on the 21/7 schedule with side effects, I persuaded my onc to let me try 5/2. Worked for me until the Ibrance stopped working. Going on new drugs soon, but the 5/2 schedule seems to be more and more common and I think is easier on your body.
I agree wholeheartedly…it makes more sense to me and I feel better! Also, the completed trials show that it’s working just as well…thank you for your response. I hope this gives others an opportunity to feel better as well !
I am happy to hear this! And thank you for the link.
I just started ibrance 2 weeks ago and I don’t have my first bloodwork until Monday, but I had issues with my neutrophils when I was on chemo and when I tried kisqali so I’m not expecting any different with this.
I started with 75mg on the 21/7 cycle and we’ll go from there.
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Experience and advice on treatment options with and without Ibrance.
Ibrance, Letrozole and Denosumab 
Breast reduction op today during my week off ibrance 
low white blood cells on Ibrance
Not sure about next step
