Capecitabine - hand and foot

[Glas0824]

I am about to start this treatment and know you can have a hand and and foot reaction. I I wonder if anyone can advise what’s the best cream to use with this? I’m in the UK.

Thanks 💓

[Melpub]

I'm on the stuff too, large dose and am waiting to have this reaction, which I haven't yet. Had one diarrhea episode and have had some gassiness and slight nausea but all this seems better. The main problem has been that the generic for Avastin, which I had, sent my lifelong low blood pressure skyrocketing to the point where my doctor said, "Don't go to the gym!" (which drives me nuts) but on a couple of little pills, I can, because my blood pressure gets low enough. But not back to normal. I heard Avastin might work better than the generic and will try that. Hand and foot can apparently be treated with standard urea cream and I also use any gook that smells good--mainly for dry skin. By the third cycle I may or may not have hand and foot: some get it and some don't.

[Figletf in reply to Melpub]

try creams and silicone socks,with regular sport socks over them so you don't slip and fall .My feet have improved by doing this.

[kearnan in reply to Melpub]

Have you have had any side effects. It is in my lungs, spine and now my liver and unfortunately, it keeps growing in the liver so she then stopped the new treatment of Tamifoxen and afinitor and put me on Xeloda, the highest dose which was 4 pills (500 mg.) after eating and then 12 hours later. First, I have had severe loss of appetite so I barely eat (although I am still overweight, explain that but it knocked me out and I was in bed for two hours barely able to move. because I had such an easy time on verzenio and falsodex injections (I would almost forget I was sick except when I went to get my injections once a month).

I was supposed to try a much lower dose but I have not done so. the more I read about this hand and foot and that even when people stopped it, they had side effects, the more I am terrified of it. I never understand how some can take one drug with minimal effects and for others, like me, I experience them.

I want a med where it does not require me to eat something first and no 12 hours in between.

[Melpub in reply to kearnan]

I've had slight nausea on the Capacetabine and once I had diarrhea. I'm taking four 500-mg pills with breakfast and three of the same with dinner; I seem to be adjusting but I had almost no problems with Ibrance. I've heard about hand-and-foot but not yet experienced it. Apparently some women have a really tough time with it and some don't. It used to be said that those without the hand-and-foot side effect were also not helped by the drug, but that seems not to be the case. Or not always. I've had higher-than-norma. but not dangerous blood pressure with the Bevacumab, but that's being handled too. The main worry is whether the dang stuff is working; I won't find out until blood tests on the 26th. In nine days, that is.

[Melpub in reply to Melpub]

P.S. Urea cream's great; I use it with socks especially at night.

[Here_now]

Hi,

I'm on my 4th cycle of cape and and foot is real for me!

The breast cancer nurse gave me a urea cream (Bioderma Atoderm Palmakera) developed for reactions to cancer treaments, I found it ok. I am currently using Aveeno cream with colloidal oatmeal that seems to work better for me (found on Amazon).

I was advised to moisterise as much as possible right from the beginning. Does it make a difference? Dont know, but I keep at it!

Good luck! I hope it works out well for you. On an optimistic note I believe it is regarded as an effective line of treatment.

[Figletf in reply to Here_now]

I had very cracked feet that creams alone did not help.I got some silicone socks and wear them over the cream.I wear regular sport socks over them to keep from falling😊

My feet have improved quite a bit!

[Here_now in reply to Figletf]

Thank you! I am ordering sillicone socks today to give it a try

[Figletf in reply to Here_now]

😁

[8576]

I believe if you look up hand and foot cream you will find plenty of info about it. The best cream is a Urea based cream, scent free. A good idea after applying at night is to wear cotton socks to bed. It keeps the cream from rubbing off. Wishing all the best.

Cheers, June S.

[Fifi313]

I use Utter cream with 20% Urea on my feet. . Use the 10% on hands. I put it on before I put my cotton peds on my feet in the morning then a small amount at bedtime . So far nothing on my hands and just 2 spots on right foot that peel. I didn’t start the cream until the peeling began-dummy! I was fine until I started 4th round of Capecitabine. But I do have redness(like brownish red) on the stress parts of both feet. The more I’m on my feet, the color increases.

[Figletf in reply to Fifi313]

please try silicone socks over the cream.Also put regular sport socks over them to keep from slipping!

My feet were terribly cracked ubtil I started doing this

[debbiedo2063]

hi

I use udderly smooth cream the red and black tub off Amazon. Im in UK. 3 cycles had no reaction re hand foot syndrome yet. I put it on morning and night.

Debra xxx

[Shellbelle124]

Hi! I didn’t have any issues for 6 months. But now I do and apply Bag Balm a few times a day. That seems to help. I keep away from walking long distances, but overall it’s not that bad. Thankfully I have been on Cape for 18 months and it has worked very well for me. Wishing the same for you!

[Photo-Bug]

When the H&F hit me at 6 weeks, doc lowered my dose which wasn't very high to start with.

Keep applying the 20% urea cream.

When it was so painful to walk, it was stopped . I also lost my big toenail.

May your journey be better than mine. The good news my tumor markers dropped.

Sharon

[queeneee]

A good tip I got from a dermatologist. Moisturise feet and wrap in cling film overnight. Light socks can help keep the film on.

[Hopeful4Cure]

I am on the 6th cycle and I never has the hand and foot thing 100%. However, my heels and big toe hurt so I use pure olive oil with pure pepperment and lavender oil and massage my feet. My tumor markers were at 70 when I started theis after ibrance and fasoldex stopped working after just 14 months. While taking the generic of Xeloda cape, my tumor markers have continusuouly been rising. Est/progest +, her2 -, luminal A, but it is not working as the tm's are now in the high 200's. Not a happy camper. Looking at options and perhaps a clinical trial. Meds work for some and not others. Mets to spine and hips.

[Glas0824 in reply to Hopeful4Cure]

Thanks I’m so sorry it hasn’t worked for you. It is just awful isn’t when you realise the treatment you pin such hope on isn’t working. I had no success at all with fulvesterant however great success with leterzol… have you had it?

[Hopeful4Cure in reply to Glas0824]

No, I have not. I think perhaps because letrozole might not be for my particular type of MBC.

[Glas0824 in reply to Hopeful4Cure]

i I’llm hormone positive and Her negative