ibrance

[Praising]

has anyone done a 2 week on 2 week off due to neutropenic? Wondering what’s after Ibrance w some progression. Had guardent test. Results tomorrow.

[Nocillo]

I didn’t have that dosing schedule, but after Ibrance I went on Verzenio and Letrozole. Still on them. I was disappointed that I only was on Ibrance for a little less than 2 years. Hopefully you’ll get longer on it.

[Merma in reply to Nocillo]

How is the Verzenio? Is the diarrhea manageable?

[Nocillo in reply to Merma]

It’s ok. Tougher than Ibrance, but still manageable. The diarrhea was only very spotty at the beginning. Now I try and watch what I eat and that helps immensely. Ice cream is a no go for sure. However, brownies and milk work fine and some of my best days are after I have that combo. Tacos are fine. I try not to eat anything unknown in a restaurant, but I don’t eat out as much as I used to. Fried food is not friendly either. Once you learn what foods to avoid, at least for me, the diarrhea becomes much less of an issue for sure. Good luck to you!

[Merma in reply to Nocillo]

Thanks for the encouraging response.

My issue is that I’m a swimmer and synchro swimmer, so diarrhea is really not an option.

[Merma]

I am starting 5 days on and 2 days off after being neutropenic resulting in 3 weeks on and 2 weeks off. I’ve been on Ibrance for over 6.5 years. Now on the lowest dose.

Dr won’t take me off anastrozole despite 2 recurrences. So I got the onc nutrition Dr to put me on metformin to hold back the er. So far it’s working. He thinks I’ll be able to be on this regimen for many years.

Please keep us posted on how you are doing on your new schedule. I am very interested in comparing notes in six months.

Best wishes to you.

[Praising in reply to Merma]

So you are still on Ibrance at reduced time length

[Merma in reply to Praising]

My neutrophils at the end of the week off, were 0.81, so I'm off for another week. Not going to retest. When I restart next week, I'll go onto the 5 day on/2 day off schedule. I'll let you know how it goes at my next cbc testing in August.

[Praising in reply to Merma]

Thanks. I go today

[Totheriver]

I have done 2 weeks on and two weeks off. This was the only way I could handle it. I have done this for 4 years and just had scans done on Monday and everything is still stable. Hope you are doing well on it too. Theresa

[catfreddie in reply to Totheriver]

I was on Ibrance for 2 weeks then taken off because of wbc and neutrofins too low. After 2 weeks blood work showed that I had not iproved enough to go back on. So I have been off 4 weeks now and think I am starting a lower dose today. I am also on Anastrazole. Fingers crossed.

[Praising in reply to Totheriver]

I am so glad you responded. I knew someone had. I’m on the lowest dose and still at 1.00 or below the week to start. But I had progression the last 6 mo. So I see today what is next.

[Totheriver]

I am on the lowest dose too. I had progression in my spine in January and I had 5 radiation treatments.

[Totheriver in reply to Totheriver]

Hope all goes well for you💕

[Praising in reply to Totheriver]

Thanks. Did your treatment change. Why did they do radiation? Pain?