Possible side effects of drugs - SHARE Metastatic ...

SHARE Metastatic Breast Cancer

6,761 members8,353 posts

Possible side effects of drugs

Betbop profile image
12 Replies

Before my diagnosis in Aug of last year I already had been diagnosed with spinal stenosis and I'm finding it has gotten much worse since I've begun treatment. I'm on Ibrance Faslodex and Xgeva. My ability to walk has been comprimised drastically and I've been experiencing numb feet at times. Has anyone else had any of these problems and if so can you offer any advice?

Written by
Betbop profile image
Betbop
To view profiles and participate in discussions please or .
Read more about...
12 Replies
Selmac profile image
Selmac

I do know that everything you mentioned are possible side effects of what you're on. The numbness should be mentioned to your Dr. It could also be neuropathy. This is what I was told while on those 3 medications.

Betbop profile image
Betbop in reply to Selmac

Thank you

Betbop profile image
Betbop in reply to Selmac

Thank you for your response

PJBinMI profile image
PJBinMI

I also had spinal stenosis before mbc, and co incidentally, have mets in that very area of the spine. I had bone mets from first cancer diagnosis, before Ibrance, and was on Femara and Zometa, then Zometa changed to Xgeva. I can tell you that when I went off Zometa, alot of the achiness of my bones got much better. I suggest talking with your onc about all this, very directly, and ask about seeing a neurosurgeon. Talk to the neurosurgeon about the condition of your spine. Stenosis can impinge on the sciatic nerve and cause numbness. I needed back surgery for a badly herniated disc and had sciatic nerve damage and my feet are numb. Physical therapy has helped alot with balance and gait and now the plan is for me to have a few weeks of PT at least a couple of times a year. My brother has diabetes and infra-red light therapy via Anodyne was very helpful to him for neuropathy in his legs and feet. My physical therapist told me that they used to do that for anybody with lower limb neuropathy and that there was always some improvement. Medicare used to cover it and does not anymore. I've looked on line and the equipment costs about $900--1000. Something else to ask your onc about.

sweeetk profile image
sweeetk in reply to PJBinMI

I have a very similar story.

Betbop profile image
Betbop in reply to PJBinMI

Thank you for your response I will speak to my oncologist

spouseM profile image
spouseM

I get numb feet and hands intermittently on Ibrance and Letrozole. For me it does not last long. Best to you, BB

Betbop profile image
Betbop in reply to spouseM

Thank you for your response

Halfpint2 profile image
Halfpint2

I’m on gabapentin for the numbness in my feet and hands. I can hardly hold a pen or pencil anymore. I can type like crazy but writing is nearly impossible.

Betbop profile image
Betbop in reply to Halfpint2

Does it give you any new side effects?

lashinator profile image
lashinator

I am a big fan of gabapentin. Aside from helping with the neuropathy, it eases the menopausal night sweats. I only take it before bed because it causes drowsiness. You can take up to 2900 mg safely! I started at 300, and have increased to 600. Seems to be doing the trick for now. Good luck.

Juliandrea profile image
Juliandrea

Betbop, I apologize, I just saw this post answering my question. Hope all goes well and you find relief quickly, did the drugs contribute to it getting worse or is it just over time gets worse.

Not what you're looking for?

You may also like...

Side effects

I've been taking Ibrance and letrozol since 2016. I started at 125 and now I'm taking 75, I'm still...

Side effects of Perjeta?

I'm trying to find a source that separates the side effects of Perjeta from those of Taxol. I am 75...

Side effects

Hi! My mom was diagnosed with metastatic breast cancer a year and a half ago and has been on...

Long Term Ibrance/letrozole Side Effects?

Hello lovelies. I'm 7 1/2 years into my first treatment protocol. Currently on 75mg Ibrance (three...

Week 4 of Ibrance side effects

Hi, I'm posting this for my Mother. She's on Ibrance and Letrozole for about a year now. She seems...